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PPAR

PPAR

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.

Found 164 products of "PPAR"

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  • Choline Fenofibrate

    CAS:
    <p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>
    Formula:C22H28ClNO5
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:421.91
  • Astaxanthin

    CAS:
    <p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>
    Formula:C40H52O4
    Purity:95.1% - 99.79%
    Color and Shape:Needles From Acetone/Light Petroleum Solid
    Molecular weight:596.84
  • SR 16832

    CAS:
    <p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>
    Formula:C17H12ClN3O4
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:357.75
  • BMS-687453

    CAS:
    <p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>
    Formula:C22H21ClN2O6
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:444.86
  • NSC-87877 disodium

    CAS:
    <p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>
    Formula:C19H13N3O7S2·2Na
    Purity:97.89%
    Color and Shape:Solid
    Molecular weight:503.42
  • Palmitelaidic Acid

    CAS:
    <p>Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.</p>
    Formula:C16H30O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:254.41
  • Avicularin

    CAS:
    <p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>
    Formula:C20H18O11
    Purity:97.02% - 99.94%
    Color and Shape:White Powder
    Molecular weight:434.35
  • GW6471

    CAS:
    <p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>
    Formula:C35H36F3N3O4
    Purity:98.23% - 99.55%
    Color and Shape:Solid
    Molecular weight:619.67
  • Icariin

    CAS:
    <p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>
    Formula:C33H40O15
    Purity:97.82% - 98.3%
    Color and Shape:Solid
    Molecular weight:676.66
  • Glabrone

    CAS:
    <p>Glabrone shows antiviral activity against influenza virus.</p>
    Formula:C20H16O5
    Purity:99.08% - 99.55%
    Color and Shape:Solid
    Molecular weight:336.34
  • FH535

    CAS:
    <p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>
    Formula:C13H10Cl2N2O4S
    Purity:98.25% - 99.5%
    Color and Shape:Solid
    Molecular weight:361.2
  • OPHIOPOGONIN D

    CAS:
    <p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>
    Formula:C44H70O16
    Purity:99.46% - ≥95%
    Color and Shape:Solid
    Molecular weight:855.02
  • SR1664

    CAS:
    <p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>
    Formula:C33H29N3O5
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:547.6
  • GW9662

    CAS:
    <p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>
    Formula:C13H9ClN2O3
    Purity:98% - 99.95%
    Color and Shape:Off-White Solid
    Molecular weight:276.68
  • LJ570

    CAS:
    <p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>
    Formula:C27H22O3
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:394.46
  • Angeloylgomisin H

    CAS:
    <p>Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.</p>
    Formula:C28H36O8
    Purity:99.84% - 99.95%
    Color and Shape:Solid
    Molecular weight:500.58
  • GW 501516

    CAS:
    <p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>
    Formula:C21H18F3NO3S2
    Purity:98.91% - 99.64%
    Color and Shape:White Solid
    Molecular weight:453.50
  • NPC 15199

    CAS:
    <p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>
    Formula:C21H23NO4
    Purity:99.93% - 99.94%
    Color and Shape:White Crystalline Powder
    Molecular weight:353.41
  • Seladelpar

    CAS:
    <p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>
    Formula:C21H23F3O5S
    Purity:99.18% - 99.41%
    Color and Shape:Solid
    Molecular weight:444.46
  • Ciprofibrate

    CAS:
    <p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>
    Formula:C13H14Cl2O3
    Purity:99.63% - >99.99%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:289.15