PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 170 products of "PPAR"
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SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formula:C17H12ClN3O4Purity:99.6%Color and Shape:SolidMolecular weight:357.75MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formula:C27H34ClNO2SPurity:99.23% - 99.84%Color and Shape:SolidMolecular weight:472.08Ref: TM-T6893
1mg35.00€5mg70.00€10mg111.00€25mg216.00€50mg354.00€100mg540.00€200mg772.00€1mL*10mM (DMSO)72.00€BMS-687453
CAS:BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgammaFormula:C22H21ClN2O6Purity:99.4%Color and Shape:SolidMolecular weight:444.86Ref: TM-T5532
1mg44.00€2mg57.00€5mg93.00€10mg137.00€25mg268.00€50mg409.00€100mg620.00€1mL*10mM (DMSO)92.00€NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurity:97.89%Color and Shape:SolidMolecular weight:503.42Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purity:99.76%Color and Shape:SolidMolecular weight:254.41Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg55.00€5mg92.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg832.00€1mL*10mM (DMSO)105.00€Tetradecylthioacetic acid
CAS:Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.
Formula:C16H32O2SPurity:99.93%Color and Shape:SolidMolecular weight:288.49GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Formula:C35H36F3N3O4Purity:98.23% - 99.55%Color and Shape:SolidMolecular weight:619.67Ref: TM-T8486
2mg35.00€5mg52.00€10mg88.00€25mg177.00€50mg311.00€100mg533.00€200mg802.00€1mL*10mM (DMSO)87.00€Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purity:97.82% - 98.3%Color and Shape:SolidMolecular weight:676.66Glabrone
CAS:Glabrone shows antiviral activity against influenza virus.Formula:C20H16O5Purity:99.08% - 99.55%Color and Shape:SolidMolecular weight:336.34FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Formula:C13H10Cl2N2O4SPurity:98.25% - 99.5%Color and Shape:SolidMolecular weight:361.2Ref: TM-T2413
5mg35.00€10mg54.00€25mg88.00€50mg156.00€100mg259.00€200mg383.00€500mg620.00€1mL*10mM (DMSO)60.00€OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formula:C44H70O16Purity:99.46% - ≥95%Color and Shape:SolidMolecular weight:855.02SR1664
CAS:SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.Formula:C33H29N3O5Purity:98.02%Color and Shape:SolidMolecular weight:547.6Ref: TM-T23389
1mg52.00€2mg74.00€5mg111.00€10mg144.00€25mg284.00€50mg411.00€100mg590.00€200mg833.00€1mL*10mM (DMSO)123.00€GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!Formula:C13H9ClN2O3Purity:98% - 99.98%Color and Shape:Off-White SolidMolecular weight:276.68LJ570
CAS:LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Formula:C27H22O3Purity:99.64%Color and Shape:SolidMolecular weight:394.46Ref: TM-T8374
1mg138.00€2mg202.00€5mg311.00€10mg445.00€25mg680.00€50mg888.00€100mg1,234.00€500mg2,475.00€1mL*10mM (DMSO)334.00€Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36T0070907
CAS:T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
Formula:C12H8ClN3O3Purity:98.25% - 99.98%Color and Shape:SolidMolecular weight:277.66GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.50Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84NPC 15199
CAS:NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.
Formula:C21H23NO4Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:353.41
