PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 170 products of "PPAR"
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LJ570
CAS:LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Formula:C27H22O3Purity:99.64%Color and Shape:SolidMolecular weight:394.46Ref: TM-T8374
1mg138.00€2mg202.00€5mg311.00€10mg445.00€25mg680.00€50mg888.00€100mg1,234.00€500mg2,475.00€1mL*10mM (DMSO)334.00€Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Formula:C13H14Cl2O3Purity:99.63% - >99.99%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:289.15L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Formula:C22H26O7Purity:97.97%Color and Shape:SolidMolecular weight:402.44GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Formula:C19H18N2O5S2Purity:99.26% - ≥95%Color and Shape:SolidMolecular weight:418.49Ref: TM-T2674
2mg44.00€5mg65.00€10mg99.00€25mg175.00€50mg349.00€100mg520.00€500mg1,134.00€1mL*10mM (DMSO)65.00€OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formula:C44H70O16Purity:99.46% - ≥95%Color and Shape:SolidMolecular weight:855.02XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formula:C24H27N7O2Purity:98.05% - 99.89%Color and Shape:SolidMolecular weight:445.52Ref: TM-T3709
2mg44.00€5mg70.00€10mg98.00€25mg178.00€50mg290.00€100mg480.00€500mg1,161.00€1mL*10mM (DMSO)84.00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purity:98.91% - 99.64%Color and Shape:White SolidMolecular weight:453.50XMD16-5
CAS:XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Formula:C23H24N6O2Purity:98.89% - 99.98%Color and Shape:SolidMolecular weight:416.48Ref: TM-T3710
1mg42.00€2mg52.00€5mg95.00€10mg137.00€25mg213.00€50mg394.00€100mg583.00€500mg1,243.00€1mL*10mM (DMSO)95.00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:SolidMolecular weight:682.75(E/Z)-Elafibranor
CAS:GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.Formula:C22H24O4SPurity:98.36%Color and Shape:SolidMolecular weight:384.49Ref: TM-T8699
2mg35.00€5mg52.00€10mg66.00€25mg104.00€50mg167.00€100mg259.00€200mg388.00€1mL*10mM (DMSO)54.00€Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg55.00€5mg92.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg832.00€1mL*10mM (DMSO)105.00€Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Formula:C31H20O10Purity:97% - 99.69%Color and Shape:SolidMolecular weight:552.48Ref: TM-T4S2128
1mg44.00€2mg66.00€5mg137.00€10mg236.00€25mg403.00€50mg582.00€100mg800.00€1mL*10mM (DMSO)177.00€Choline Fenofibrate
CAS:Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic
Formula:C22H28ClNO5Purity:98.82%Color and Shape:SolidMolecular weight:421.91Pirinixic Acid
CAS:Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Formula:C14H14ClN3O2SPurity:98.27% - 99.92%Color and Shape:SolidMolecular weight:323.8Ref: TM-T2269
1g350.00€10mg48.00€25mg64.00€50mg79.00€100mg105.00€200mg148.00€500mg236.00€1mL*10mM (DMSO)47.00€Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).
Formula:C30H29N3O4Purity:98.1% - 98.21%Color and Shape:SolidMolecular weight:495.57GSK3787
CAS:GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.Formula:C15H12ClF3N2O3SPurity:98% - 99.56%Color and Shape:SolidMolecular weight:392.78Ref: TM-T1941
5mg55.00€10mg87.00€25mg173.00€50mg309.00€100mg520.00€500mg1,111.00€1mL*10mM (DMSO)55.00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Formula:C25H27F3N2O3Purity:97.77%Color and Shape:SolidMolecular weight:460.49Ref: TM-T39516
1mg114.00€5mg260.00€10mg389.00€25mg703.00€50mg1,054.00€100mg1,468.00€1mL*10mM (DMSO)264.00€
