PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 164 products of "PPAR"
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Retinoic acid
CAS:<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Formula:C10H11ClO3Purity:99.47% - 99.8%Color and Shape:Pale Yellow SolidMolecular weight:214.65MA-0204
CAS:<p>MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,</p>Formula:C25H27F3N2O4Purity:97.8%Color and Shape:SolidMolecular weight:476.49Oleoylethanolamide
CAS:<p>Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.</p>Formula:C20H39NO2Purity:99.98%Color and Shape:SolidMolecular weight:325.53Fenofibric acid
CAS:<p>Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.</p>Formula:C17H15ClO4Purity:99.36%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:318.75MK-0533
CAS:<p>MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.</p>Formula:C28H24F3NO6Purity:99.03%Color and Shape:SoildMolecular weight:527.49Arhalofenate
CAS:<p>Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.</p>Formula:C19H17ClF3NO4Purity:98.97%Color and Shape:SolidMolecular weight:415.79Pioglitazone
CAS:<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Formula:C19H20N2O3SPurity:95% - 99.57%Color and Shape:White PowderMolecular weight:356.44Sulotroban potassium
<p>Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.</p>Formula:C16H16KNO5SPurity:98.02%Color and Shape:SoildMolecular weight:373.46MCC-555
CAS:<p>MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.</p>Formula:C21H16FNO3SPurity:99.07% - 99.82%Color and Shape:SolidMolecular weight:381.42Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS:<p>Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.</p>Formula:C24H23NO5SPurity:99.59%Color and Shape:SoildMolecular weight:437.51Nuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidWAY-620472
CAS:<p>WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.</p>Formula:C23H21N5OSPurity:98.07%Color and Shape:SolidMolecular weight:415.51PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Formula:C23H28FN7O3Color and Shape:SolidMolecular weight:469.51Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Formula:C21H22N2O6Color and Shape:SolidMolecular weight:398.409CUDA
CAS:<p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>Formula:C19H36N2O3Purity:97.585%Color and Shape:SolidMolecular weight:340.58-iso Prostaglandin F1α
CAS:<p>8-iso Prostaglandin F1α induces vasoconstrictor effects in (PA),(PV) and (MA) through activation of TXA2R, tyrosine kinases and Rho kinases.</p>Formula:C20H36O5Color and Shape:SolidMolecular weight:356.5CC618
CAS:<p>CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.</p>Formula:C20H15F6N3O3S2Purity:99.94%Color and Shape:SolidMolecular weight:523.47PPAR agonist 6
<p>PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].</p>Color and Shape:Odour SolidSulotroban
CAS:<p>sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.</p>Formula:C16H17NO5SPurity:98.86% - 99.88%Color and Shape:SolidMolecular weight:335.37
![Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT63898.webp&w=3840&q=75)
