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FXR

FXR

Farnesoid X Receptor (FXR) is a nuclear receptor that plays a key role in the regulation of bile acid homeostasis, lipid metabolism, and glucose regulation. FXR is a potential therapeutic target for treating liver diseases, metabolic disorders, and cardiovascular diseases. FXR inhibitors can modulate these pathways, offering insights into disease mechanisms and therapeutic strategies. At CymitQuimica, we provide a range of FXR inhibitors to support your research in hepatology, metabolism, and drug development.

Found 58 products of "FXR"

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  • Omesdafexor
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    Omesdafexor

    CAS:
    <p>Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.</p>
    Formula:C34H43N3O3
    Color and Shape:Solid
    Molecular weight:541.72

    Ref: TM-T63818

  • NR1H4 activator 1
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    NR1H4 activator 1

    CAS:
    <p>NR1H4 activator 1 is a potent and selective agonist of Famesoid X Receptor (FXR).</p>
    Formula:C34H53NO7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:619.85

    Ref: TM-T12251

  • FXR agonist 12
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    FXR agonist 12

    CAS:
    <p>FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.</p>
    Formula:C26H44O3
    Color and Shape:Solid
    Molecular weight:404.626

    Ref: TM-T205709

  • BMS-986339
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    BMS-986339

    CAS:
    <p>BMS-986339: oral, potent FXR agonist; binds to His298/ASN287; for PBC, PSC, NASH, anti-fibrosis research.</p>
    Formula:C35H41F4N3O4
    Color and Shape:Solid
    Molecular weight:643.71

    Ref: TM-T73155

  • Danifexor
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    Danifexor

    CAS:
    <p>Danifexor is an agonist of the farnesoid X receptor (Farnesoid X receptor).</p>
    Formula:C29H20Cl2N2O5
    Color and Shape:Solid
    Molecular weight:547.386

    Ref: TM-T206509

  • FXR/CES2 modulator 1
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    FXR/CES2 modulator 1

    CAS:
    <p>Compound LE-77, known as FXR/CES2 modulator 1, functions as a dual regulator that activates FXR and inhibits CES2. It effectively mitigates the intestinal toxicity of irinotecan.</p>
    Formula:C27H21Cl2NO5
    Color and Shape:Solid
    Molecular weight:510.36

    Ref: TM-T200901

  • Lecufexor
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    Lecufexor

    CAS:
    <p>Lecufexor is an agonist of the farnesoid X receptor (FXR).</p>
    Formula:C32H21Cl3N2O5
    Color and Shape:Solid
    Molecular weight:619.88

    Ref: TM-T201138

  • BAR-2227
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    BAR-2227

    CAS:
    <p>BAR-2227 (compound 3a) functions as an FXR agonist and a LIFR inhibitor. It is utilized in the study of liver fibrosis and inflammation.</p>
    Formula:C24H17Cl2NO4
    Color and Shape:Solid
    Molecular weight:454.30

    Ref: TM-T200662