Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 300 products of "Dehydrogenase"
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MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormula:C22H19NO7SColor and Shape:SolidMolecular weight:441.45(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Formula:C21H27NO3Purity:98%Color and Shape:SolidMolecular weight:341.44IGUANA-1
CAS:IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.Formula:C27H26ClN3O4Purity:99.08%Color and Shape:SolidMolecular weight:491.97Ref: TM-T73377
1mg86.00€5mg180.00€10mg283.00€25mg530.00€50mg797.00€100mg1,159.00€1mL*10mM (DMSO)188.00€DSM705
CAS:DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Formula:C19H19F3N6OColor and Shape:SolidMolecular weight:404.397Octanoyl Coenzyme A (sodium salt)
Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.Formula:C29H49N7NaO17P3SColor and Shape:SolidMolecular weight:915.71MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formula:C26H21F6N2NaO5Color and Shape:SolidMolecular weight:578.44hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formula:C22H15F3N4O3Purity:98%Color and Shape:SolidMolecular weight:440.37D-Lactate dehydrogenase
CAS:D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Color and Shape:SolidBMS-770767
CAS:BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formula:C19H18ClN3O2Color and Shape:SolidMolecular weight:355.82IGUANA-1 free base
CAS:IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Formula:C26H24ClN3O2Color and Shape:SolidMolecular weight:445.94SCD1 inhibitor-3
CAS:SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formula:C19H16FN7O2Purity:99.5%Color and Shape:SolidMolecular weight:393.37Ref: TM-T38683
1mg92.00€5mg187.00€10mg298.00€25mg507.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)205.00€PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formula:C17H23AsCl2N2O2S2Color and Shape:SolidMolecular weight:497.3311β-HSD1 inibitor 17
CAS:11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formula:C22H20F3N3O2SPurity:99.26% - 99.72%Color and Shape:SoildMolecular weight:447.47LDHA-IN-3
CAS:LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formula:C13H9F3SePurity:99.71%Color and Shape:SolidMolecular weight:301.17Ref: TM-T39805
1mg52.00€5mg113.00€10mg177.00€25mg371.00€50mg517.00€100mg707.00€200mg973.00€1mL*10mM (DMSO)124.00€WAY-311610
CAS:WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.Formula:C16H13F3N4O2Purity:99.75%Color and Shape:SolidMolecular weight:350.3DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Formula:C17H12ClF6N5O2Color and Shape:SolidMolecular weight:467.753DHODH-IN-18
CAS:DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formula:C21H16ClF5N6O4Color and Shape:SolidMolecular weight:546.8418β-Glycyrrhetyl-3-O-sulfate
CAS:18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formula:C30H46O7SColor and Shape:SolidMolecular weight:550.75MCI-INI-3
CAS:MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formula:C21H15N3O4Color and Shape:SolidMolecular weight:373.36PDK-IN-1
CAS:PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formula:C20H16BrN7OColor and Shape:SolidMolecular weight:450.29
