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Dehydrogenase

Dehydrogenase

Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.

Found 267 products of "Dehydrogenase"

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  • hDHODH-IN-13

    CAS:
    <p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>
    Color and Shape:Soild
  • PDK-IN-2


    <p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>
    Formula:C17H23AsCl2N2O2S2
    Color and Shape:Solid
    Molecular weight:497.33
  • SCD1 inhibitor-3

    CAS:
    <p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>
    Formula:C19H16FN7O2
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:393.37
  • DSM705

    CAS:
    <p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>
    Formula:C19H19F3N6O
    Color and Shape:Solid
    Molecular weight:404.397
  • 2,3-Dihydroxybenzaldehyde

    CAS:
    <p>2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.</p>
    Formula:C7H6O3
    Color and Shape:Solid
    Molecular weight:138.12
  • 11β-HSD1 inibitor 19

    CAS:
    <p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>
    Formula:C19H16ClF4N3O2S
    Purity:99.58%
    Color and Shape:Soild
    Molecular weight:461.86
  • Nedosiran sodium

    CAS:
    <p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>
    Color and Shape:Solid
  • Octanoyl Coenzyme A (sodium salt)


    <p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>
    Formula:C29H49N7NaO17P3S
    Color and Shape:Solid
    Molecular weight:915.71
  • DSM1465


    <p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>
    Formula:C17H12ClF6N5O2
    Color and Shape:Solid
    Molecular weight:467.753
  • D-Lactate dehydrogenase

    CAS:
    <p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>
    Color and Shape:Solid
  • MTHFD2-IN-2


    <p>MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>
    Formula:C22H18N4O5
    Color and Shape:Solid
    Molecular weight:418.4
  • BVT-2733 hydrochloride

    CAS:
    <p>BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.</p>
    Formula:C17H22Cl2N4O3S2
    Color and Shape:Solid
    Molecular weight:465.42
  • BMS-770767

    CAS:
    <p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>
    Formula:C19H18ClN3O2
    Color and Shape:Solid
    Molecular weight:355.82
  • Osmanthuside H

    CAS:
    <p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>
    Formula:C19H28O11
    Color and Shape:Solid
    Molecular weight:432.422
  • LDHA-IN-3

    CAS:
    <p>LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.</p>
    Formula:C13H9F3Se
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:301.17
  • MTHFD2-IN-1


    <p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>
    Formula:C24H21NO6
    Color and Shape:Solid
    Molecular weight:419.43
  • MTHFD2-IN-4 sodium


    <p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>
    Formula:C26H21F6N2NaO5
    Color and Shape:Solid
    Molecular weight:578.44
  • 18β-Glycyrrhetyl-3-O-sulfate

    CAS:
    <p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>
    Formula:C30H46O7S
    Color and Shape:Solid
    Molecular weight:550.75
  • 11β-HSD1 inibitor 17

    CAS:
    <p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>
    Formula:C22H20F3N3O2S
    Purity:99.26% - 99.72%
    Color and Shape:Soild
    Molecular weight:447.47
  • LDHA-IN-8

    CAS:
    <p>LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.</p>
    Formula:C15H14N4O2
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:282.3