Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 300 products of "Dehydrogenase"
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hDHODH-IN-13
CAS:hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inColor and Shape:SoildPDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formula:C17H23AsCl2N2O2S2Color and Shape:SolidMolecular weight:497.33KOTX1
CAS:KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Formula:C17H16FN3O2Color and Shape:SolidMolecular weight:313.33D-Lactate dehydrogenase
CAS:D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Color and Shape:SolidMCI-INI-3
CAS:MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formula:C21H15N3O4Color and Shape:SolidMolecular weight:373.36Necroptosis-IN-3
CAS:Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formula:C12H17NOSPurity:99.85%Color and Shape:SoildMolecular weight:223.33DHODH-IN-23
CAS:DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
Formula:C24H21ClFNO4Purity:99.7%Color and Shape:SolidMolecular weight:441.88CM121
CAS:CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.Formula:C24H17FN4O3SColor and Shape:SolidMolecular weight:460.482,3-Dihydroxybenzaldehyde
CAS:2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.Formula:C7H6O3Color and Shape:SolidMolecular weight:138.12Osmanthuside H
CAS:Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formula:C19H28O11Color and Shape:SolidMolecular weight:432.422WQQ-345
WQQ-345, a BCAT1 inhibitor, exhibits an IC50 of 10.8 mM. In 67R cells, it reduces α-KG levels and upregulates H3K27me3 expression while downregulating the expression of glycolytic enzymes (PFKP and LDHA), leading to impaired glycolytic activity. Additionally, WQQ-345 demonstrates tumor-suppressive activity in a 67R subcutaneous xenograft model.Formula:C10H17NO2Color and Shape:SolidMolecular weight:183.25TC HSD 21
CAS:TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formula:C17H12BrNO3S2Purity:99.32%Color and Shape:SolidMolecular weight:422.32Ref: TM-T13100
1mg42.00€5mg90.00€10mg137.00€25mg239.00€50mg344.00€100mg462.00€200mg625.00€1mL*10mM (DMSO)90.00€11β-HSD1-IN-11
CAS:11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formula:C15H11F3O3SPurity:99.61%Color and Shape:SoildMolecular weight:328.31Ref: TM-T60149
1mg109.00€5mg241.00€10mg355.00€25mg532.00€50mg745.00€100mg1,018.00€500mg2,043.00€1mL*10mM (DMSO)239.00€BMS-770767
CAS:BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formula:C19H18ClN3O2Color and Shape:SolidMolecular weight:355.82SKI2852
CAS:SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.Formula:C27H34FN5O4SPurity:99.89%Color and Shape:SolidMolecular weight:543.65PDK-IN-1
CAS:PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formula:C20H16BrN7OColor and Shape:SolidMolecular weight:450.29DSM705
CAS:DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Formula:C19H19F3N6OColor and Shape:SolidMolecular weight:404.397ALDH1A3-IN-1
CAS:ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].Formula:C13H18BrNOColor and Shape:SolidMolecular weight:284.19Aldehyde dehydrogenase (NAD(P))
CAS:ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.Color and Shape:Solid4-Isopropoxybenzaldehyde
CAS:ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.Formula:C10H12O2Purity:99.00%Color and Shape:SolidMolecular weight:164.2
