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AhR

AhR

The Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor that plays a critical role in the regulation of biological responses to environmental contaminants, such as dioxins. AhR is also involved in the metabolism of xenobiotics and the regulation of immune responses, cell proliferation, and differentiation. Dysregulation of AhR signaling is linked to various diseases, including cancer and autoimmune disorders. At CymitQuimica, we offer a range of AhR inhibitors to support your research in toxicology, cancer biology, and immunology.

Found 41 products of "AhR"

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  • L-Kynurenine

    CAS:
    <p>L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!</p>
    Formula:C10H12N2O3
    Purity:98.44% - 99.91%
    Color and Shape:Light Yellow Crystalline
    Molecular weight:208.21
  • BAY-218

    CAS:
    <p>Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.</p>
    Formula:C20H17ClFN3O3
    Purity:99.46% - 99.85%
    Color and Shape:Solid
    Molecular weight:401.82
  • Carbidopa

    CAS:
    <p>Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).</p>
    Formula:C10H14N2O4
    Purity:98.01% - ≥98%
    Color and Shape:Solid
    Molecular weight:226.23
  • Tapinarof

    CAS:
    <p>Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.</p>
    Formula:C17H18O2
    Purity:99.64% - >99.99%
    Color and Shape:Solid
    Molecular weight:254.32
  • PDM11

    CAS:
    <p>PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)</p>
    Formula:C16H15ClO2
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:274.74
  • ITE

    CAS:
    <p>ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.</p>
    Formula:C14H10N2O3S
    Purity:97.91% - 99.14%
    Color and Shape:Solid
    Molecular weight:286.31
  • CAY 10465

    CAS:
    <p>CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki &gt;100000 nM).</p>
    Formula:C15H9Cl2F3
    Purity:98.80%
    Color and Shape:Solid
    Molecular weight:317.13
  • StemRegenin 1

    CAS:
    <p>StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.</p>
    Formula:C24H23N5OS
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:429.54
  • PDM2

    CAS:
    <p>PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.</p>
    Formula:C14H9Cl3
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:283.58
  • Skatole

    CAS:
    <p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>
    Formula:C9H9N
    Purity:99.74%
    Color and Shape:Leaves From Petroleum Ether; White-Brown Scales Solid
    Molecular weight:131.17
  • Brevifolincarboxylic acid

    CAS:
    <p>Natural α-glucosidase inhibitor from Polygonum capitatum; blocks AhR with 323.46 μM IC50.</p>
    Formula:C13H8O8
    Purity:99.42% - 99.59%
    Color and Shape:Solid
    Molecular weight:292.2
  • 1,4-Chrysenequinone

    CAS:
    <p>1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).</p>
    Formula:C18H10O2
    Purity:99.07% - 99.84%
    Color and Shape:Solid
    Molecular weight:258.27
  • Pifithrin-α hydrobromide

    CAS:
    <p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>
    Formula:C16H18N2OS·HBr
    Purity:97.71% - >99.99%
    Color and Shape:Solid
    Molecular weight:367.3
  • YL-109

    CAS:
    <p>YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.</p>
    Formula:C14H11NO2S
    Purity:99.77% - ≥95%
    Color and Shape:Solid
    Molecular weight:257.31
  • DiMNF

    CAS:
    <p>Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.</p>
    Formula:C21H16O4
    Purity:97.60%
    Color and Shape:Solid
    Molecular weight:332.35
  • L-Kynurenine-d4

    CAS:
    <p>L-Kynurenine-d4 is a deuterated isotope compound of L-Kynurenine. L-Kynurenine is a metabolite of tryptophan and an endogenous agonist of the AHR.</p>
    Formula:C10H8D4N2O3
    Color and Shape:Solid
    Molecular weight:212.24
  • D-Kynurenine

    CAS:
    <p>D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.</p>
    Formula:C10H12N2O3
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:208.21
  • Phortress

    CAS:
    <p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>
    Formula:C20H25Cl2FN4OS
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:459.41
  • Prochloraz

    CAS:
    <p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>
    Formula:C15H16Cl3N3O2
    Purity:99.75% - 99.79%
    Color and Shape:Colorless Solid
    Molecular weight:376.67
  • CAY10464

    CAS:
    <p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>
    Formula:C15H12Cl2O
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:279.16