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Lipoxygenase

Lipoxygenase

Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.

Found 124 products of "Lipoxygenase"

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  • Indirubin-3'-monoxime

    CAS:
    <p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>
    Formula:C16H11N3O2
    Purity:99.55%
    Color and Shape:Dark Red Solid
    Molecular weight:277.28
  • Phenethyl ferulate

    CAS:
    <p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>
    Formula:C18H18O4
    Purity:99.88% - 99.91%
    Color and Shape:Solid
    Molecular weight:298.33
  • Tepoxalin

    CAS:
    <p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>
    Formula:C20H20ClN3O3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:385.84
  • 3-Hydroxycoumarin

    CAS:
    <p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>
    Formula:C9H6O3
    Purity:99.5% - 99.77%
    Color and Shape:Solid
    Molecular weight:162.14
  • ML355

    CAS:
    <p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>
    Formula:C21H19N3O4S2
    Purity:98.02% - 98.2%
    Color and Shape:Solid
    Molecular weight:441.52
  • Psoralidin

    CAS:
    <p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>
    Formula:C20H16O5
    Purity:98% - 99.61%
    Color and Shape:Solid
    Molecular weight:336.34
  • Caffeic Acid

    CAS:
    <p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>
    Formula:C9H8O4
    Purity:98.89% - 99.3%
    Color and Shape:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)
    Molecular weight:180.16
  • PGS-IN-1

    CAS:
    <p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>
    Formula:C19H26O3
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:302.41
  • 4',5-Dihydroxyflavone

    CAS:
    <p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>
    Formula:C15H10O4
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:254.24
  • S-(+)-Marmesin

    CAS:
    <p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>
    Formula:C14H14O4
    Purity:98.00% - ≥98%
    Color and Shape:Solid
    Molecular weight:246.26
  • LOX-IN-3 dihydrochloride

    CAS:
    <p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>
    Formula:C13H15Cl2FN2O2S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:353.24
  • 2,5-Di-tert-butylhydroquinone

    CAS:
    <p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>
    Formula:C14H22O2
    Purity:97.11%
    Color and Shape:Pelletslargecrystals
    Molecular weight:222.32
  • ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE

    CAS:
    <p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>
    Formula:C12H13NO3
    Purity:98.9%
    Color and Shape:Off-White To Light Tan Crystalline Powder
    Molecular weight:219.24
  • Xanthatin

    CAS:
    <p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>
    Formula:C15H18O3
    Purity:98.48% - 99.96%
    Color and Shape:Solid
    Molecular weight:246.3
  • BI-0115

    CAS:
    <p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>
    Formula:C15H14ClN3O
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:287.74
  • Malotilate

    CAS:
    <p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>
    Formula:C12H16O4S2
    Purity:99.79% - 99.79%
    Color and Shape:Solid
    Molecular weight:288.38
  • 3-O-Acetyl-11-hydroxy-β-boswellic acid

    CAS:
    <p>3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).</p>
    Formula:C32H50O5
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:514.74
  • Licofelone

    CAS:
    <p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>
    Formula:C23H22ClNO2
    Purity:99.25%
    Color and Shape:Yellowish Solid
    Molecular weight:379.88
  • Phenidone

    CAS:
    <p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>
    Formula:C9H10N2O
    Purity:97.24%
    Color and Shape:White Solid Solid Crystalline
    Molecular weight:162.19
  • Chebulagic acid

    CAS:
    <p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>
    Formula:C41H30O27
    Purity:97.82% - 99.8%
    Color and Shape:Solid
    Molecular weight:954.66