Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 124 products of "Lipoxygenase"
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Linoleyl alcohol
CAS:<p>Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].</p>Formula:C18H34OPurity:98.12%Color and Shape:SolidMolecular weight:266.463-Hydroxycoumarin
CAS:<p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>Formula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.14ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Formula:C21H19N3O4S2Purity:98.02% - 98.2%Color and Shape:SolidMolecular weight:441.5211-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25CAY10698
CAS:<p>CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).</p>Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.645-LOX inhibitor
CAS:<p>5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is an itraconazole impurity, a LOX-5 inhibitor.</p>Formula:C22H27N5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.48a-Boswellic Acid
CAS:Controlled Product<p>Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.<br>References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);<br></p>Formula:C30H48O3Color and Shape:NeatMolecular weight:456.70Golocdacimab
CAS:<p>Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.</p>Purity:95%Color and Shape:Liquid4-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24tHGA
CAS:<p>tHGA is a potent inhibitor of lipoxygenase.</p>Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38BI-L 357
CAS:<p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4L 652343
CAS:<p>L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.</p>Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.482-TEDC
CAS:<p>2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.</p>Formula:C16H13NO4SPurity:99.75%Color and Shape:SolidMolecular weight:315.34Atreleuton
CAS:<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37RWJ 63556
CAS:<p>RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.</p>Formula:C11H10FNO3S2Purity:99.92%Color and Shape:SolidMolecular weight:287.33AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58PF-4191834
CAS:<p>PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.</p>Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:393.5
