Phospholipase
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.
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Halopemide
CAS:59831-65-1
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human …
Formula:
C21H22ClFN4O2
Purity:
96.29%
Color and Shape:
Solid
Molecular weight:
416.88
Ref: TM-T15461
| 1mg | 34.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 236.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 511.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
ML299
CAS:1426916-00-8
ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 …
Formula:
C23H26BrFN4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
489.38
Ref: TM-T8968
| 1mg | 255.00 € | ||
| 5mg | 1,034.00 € | ||
| 500µg | 141.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
ASM-IN-1
CAS:2913151-46-7
ASM-IN-1: Oral acid sphingomyelinase inhibitor, IC50 = 1.5 µM; reduces lipid plaques, plasma ceramide, Ox-LDL.
Formula:
C16H12BrN3O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
390.19
Ref: TM-T74778
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
5-HT1A modulator 1
CAS:142477-34-7
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor …
Formula:
C21H25N3O2S
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
383.51
Ref: TM-T10168
| 1mg | 241.00 € | ||
| 5mg | 598.00 € | ||
| 10mg | 799.00 € | ||
| 25mg | 1,182.00 € | ||
| 50mg | 1,610.00 € | ||
| 100mg | 2,159.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Desketoraloxifene
CAS:216570-81-9
Desketoraloxifene is a selective estrogen receptor modulator, inhibiting mammalian PLD (PLD1 and PLD2).
Formula:
C27H27NO3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
445.57
Ref: TM-T9001
| 25mg | 761.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
D-Erythro-dihydrosphingosine
CAS:764-22-7
D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) inhibits arachidonic acid release and cPLA2α activity.
Formula:
C18H39NO2
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
301.51
Ref: TM-T13632
| 1mg | 34.00 € | ||
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 23 Jan 2025
Atg4B-IN-2
CAS:2765008-88-4
Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists …
Formula:
C21H30O3
Purity:
98.86%
Color and Shape:
Liquid
Molecular weight:
330.46
Ref: TM-T60967
| 1mg | 111.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 637.00 € | ||
| 50mg | 928.00 € | ||
| 100mg | 1,394.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Lp-PLA2-IN-16
CAS:1865780-73-9
Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in …
Formula:
C22H17F5N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
480.39
Ref: TM-T79076
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Lp-PLA2-IN-12
CAS:2637485-14-2
Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease …
Formula:
C24H23F2N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
467.47
Ref: TM-T79010
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
VU0155069
CAS:1130067-06-9
VU0155069, a selective PLD1 inhibitor (IC50: 46 nM), halts cancer cell migration in transwell assays.
Formula:
C26H27ClN4O2
Purity:
98.32%
Color and Shape:
Solid
Molecular weight:
462.97
Ref: TM-T17239
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 320.00 € | ||
| 100mg | 546.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Lp-PLA2-IN-3
CAS:2196245-16-4
Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.
Formula:
C20H13ClF3N3O3S
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
467.85
Ref: TM-T11874
| 1mg | 95.00 € | ||
| 2mg | 139.00 € | ||
| 5mg | 226.00 € | ||
| 10mg | 357.00 € | ||
| 25mg | 592.00 € | ||
| 50mg | 836.00 € | ||
| 100mg | 1,113.00 € | ||
| 500mg | 2,244.00 € | ||
| 1mL*10mM (DMSO) | 232.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Lp-PLA2-IN-15
CAS:1865796-11-7
Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in …
Formula:
C22H17F5N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
480.39
Ref: TM-T79075
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 23 Jan 2025
Lp-PLA2-IN-2
CAS:2071636-15-0
Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f …
Formula:
C19H23FN2O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
394.46
Ref: TM-T11873
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
VU0364739
CAS:1244639-78-8
VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces …
Formula:
C26H27FN4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
446.52
Ref: TM-T78161
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 6 Feb 2025
Rilapladib
CAS:412950-08-4
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) …
Formula:
C40H38F5N3O3S
Purity:
97.29%
Color and Shape:
Solid
Molecular weight:
735.8
Ref: TM-T16751
| 1mg | 91.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 364.00 € | ||
| 25mg | 609.00 € | ||
| 50mg | 866.00 € | ||
| 100mg | 1,179.00 € | ||
| 1mL*10mM (DMSO) | 367.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
Lp-PLA2-IN-13
CAS:2756855-62-4
Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].
Formula:
C22H17F5N4O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
496.39
Ref: TM-T79073
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
Varespladib methyl
CAS:172733-08-3
Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase …
Formula:
C22H22N2O5
Purity:
100% - 99.69%
Color and Shape:
Solid
Molecular weight:
394.42
Ref: TM-T17218
| 1mg | 115.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 446.00 € | ||
| 25mg | 733.00 € | ||
| 50mg | 1,006.00 € | ||
| 100mg | 1,374.00 € | ||
| 500mg | 2,775.00 € | ||
| 1mL*10mM (DMSO) | 420.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
Lp-PLA2-IN-14
CAS:2756855-66-8
Lp-PLA2-IN-14 (Compound 19), an inhibitor of rhLp-PLA2, exhibits a potent inhibitory effect with a pIC50 …
Formula:
C16H14F3N3O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
353.3
Ref: TM-T79074
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Thursday 6 Feb 2025
Ecopladib
CAS:381683-92-7
Ecopladib inhibits cPLA2α with IC50 of 0.15 μM (micelles) & 0.11 μM (rat blood).
Formula:
C39H33Cl3N2O5S
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
748.11
Ref: TM-T11149
| 1mg | 775.00 € | ||
| 5mg | 1,551.00 € | ||
| 10mg | 2,098.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 6 Feb 2025
FAAH/cPLA2α-IN-1
CAS:1696401-38-3
FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with …
Formula:
C19H26N4O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
390.43
Ref: TM-T82421
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 6 Feb 2025
