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Phospholipase

Phospholipase

Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.

Found 82 products of "Phospholipase"

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  • MJ33 lithium salt

    CAS:
    <p>MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, inhibits PLA2 activity, and can be used to study acute lung injury.</p>
    Formula:C22H43F3LiO6P
    Purity:99%
    Color and Shape:Solid
    Molecular weight:498.48
  • PACOCF3

    CAS:
    <p>PACOCF3, a phospholipase A2 inhibitor, hinders Ca2+ signaling with an IC50 of 3.8 μM in renal cells.</p>
    Formula:C17H31F3O
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:308.42
  • BMS493

    CAS:
    <p>BMS493 is an inverse agonist of RAR that inhibits retinoic acid-induced differentiation and inhibits the increase in phospholipase A2 activity.</p>
    Formula:C29H24O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:404.5
  • Bromoenol lactone

    CAS:
    <p>NeurokininBromoenol lactone ((6E)-Bromoenol lactone) is an iPLA2β and serine protease inhibitor that attenuates nicotine-induced breast cancer cell proliferation.</p>
    Formula:C16H13BrO2
    Color and Shape:Solid
    Molecular weight:317.18
  • LEI-401

    CAS:
    <p>LEI-401 is a NAPE-PLD inhibitor.LEI-401 reduces the level of n-acyl ethanolamines in the brain of free-ranging mice and modulates their emotional behaviour.</p>
    Formula:C24H31N5O2
    Purity:99.79% - 99.79%
    Color and Shape:Solid
    Molecular weight:421.54
  • ML348

    CAS:
    <p>ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).</p>
    Formula:C18H17ClF3N3O3
    Purity:99% - 99.88%
    Color and Shape:Solid
    Molecular weight:415.79
  • BAPTA

    CAS:
    <p>BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.</p>
    Formula:C22H24N2O10
    Purity:96.28% - ≥95%
    Color and Shape:White Solid
    Molecular weight:476.43
  • N-(p-amylcinnamoyl) Anthranilic Acid

    CAS:
    <p>N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.</p>
    Formula:C21H23NO3
    Purity:99.35% - 99.67%
    Color and Shape:Solid
    Molecular weight:337.41
  • ST271

    CAS:
    <p>ST271 is an effective protein tyrosine kinase (PTK) inhibitor.</p>
    Formula:C16H20N2O2
    Purity:98.94%
    Color and Shape:Solid
    Molecular weight:272.34
  • ONO-RS-082

    CAS:
    <p>ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor. </p>
    Formula:C21H22ClNO3
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:371.86
  • Varespladib

    CAS:
    <p>Varespladib (LY315920) inhibits hnsPLA2 effectively (IC50=7 nM), studied for sickle cell, VOC, and acute coronary syndrome.</p>
    Formula:C21H20N2O5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:380.39
  • ML-211

    CAS:
    <p>ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)</p>
    Formula:C25H30N4O2
    Purity:97.07%
    Color and Shape:Solid
    Molecular weight:418.53
  • Tanshinone I

    CAS:
    <p>Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.</p>
    Formula:C18H12O3
    Purity:98.31% - 98.70%
    Color and Shape:Solid
    Molecular weight:276.29
  • Rhamnetin

    CAS:
    <p>Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities.</p>
    Formula:C16H12O7
    Purity:99.61% - 99.905%
    Color and Shape:Solid
    Molecular weight:316.26
  • trans-Benzylideneacetone

    CAS:
    <p>trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.</p>
    Formula:C10H10O
    Purity:97.48%
    Color and Shape:Light Yellow Low Melting Crystalline Mass
    Molecular weight:146.19
  • 1-Naphthaleneacetic acid

    CAS:
    <p>1-Naphthaleneacetic acid, an auxin-like synthetic plant hormone, boosts rooting in horticulture.</p>
    Formula:C12H10O2
    Purity:98.67%
    Color and Shape:Needles From Water White To Off White Crystals
    Molecular weight:186.21
  • Cambinol

    CAS:
    <p>Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.</p>
    Formula:C21H16N2O2S
    Purity:98.02% - 99.83%
    Color and Shape:Solid
    Molecular weight:360.43
  • ML-298

    CAS:
    <p>ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).</p>
    Formula:C22H23F3N4O2
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:432.44
  • RPI-1

    CAS:
    <p>RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.</p>
    Formula:C17H15NO4
    Purity:98.91% - ≥95%
    Color and Shape:Solid
    Molecular weight:297.31
  • U-73343

    CAS:
    <p>U-73343 is an inactive analog of U-73122 and can be used as a negative control. U-73122 dose-dependently inhibits acid secretion irrespective of the stimulant.</p>
    Formula:C29H42N2O3
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:466.66