Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(2,949 products)
- Antibiotic(918 products)
- Antifection(23 products)
- DHFR(32 products)
- DNA/RNA Synthesis(706 products)
- HBV(176 products)
- HIV Protease(447 products)
- HSV(91 products)
- Integrase(2 products)
- Ribosome(13 products)
Show 2 more subcategories
Found 5832 products of "Microbiology/Virology"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Ambelline
CAS:<p>Ambelline has antitumor activity.</p>Formula:C18H21NO5Purity:98%Color and Shape:SolidMolecular weight:331.36Carbodine
CAS:<p>Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.</p>Formula:C10H15N3O4Purity:98%Color and Shape:SolidMolecular weight:241.24Elongation factor P-IN-1
<p>EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.</p>Formula:C14H31N3O2Color and Shape:SolidMolecular weight:273.41Benzohydroxamic acid
CAS:<p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>Formula:C7H7NO2Color and Shape:SolidMolecular weight:137.136GSK 932121
CAS:<p>GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.</p>Formula:C20H15ClF3NO4Purity:98%Color and Shape:SolidMolecular weight:425.79L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Formula:C35H33ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:597.17Anti-Influenza agent 3
<p>Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).</p>Formula:C16H22ClNOSColor and Shape:SolidMolecular weight:311.87Purine phosphoribosyltransferase-IN-1
<p>Compound (S,R)-48 inhibits Pf, Pv, & Tbr PRT with Ki of 50, 20, 2 nM.</p>Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Formula:C17H19N5O5Color and Shape:SolidMolecular weight:373.363Werner syndrome RecQ helicase-IN-2
CAS:<p>Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.</p>Formula:C32H34F3N9O5Purity:99.02%Color and Shape:SolidMolecular weight:681.67Polθ-IN-8
CAS:<p>Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.</p>Formula:C22H22ClN7O3SColor and Shape:SolidMolecular weight:499.97SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Formula:C36H38N2O2Color and Shape:SolidMolecular weight:530.7Antitubercular agent-11
<p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>Formula:C16H15N3O4Color and Shape:SolidMolecular weight:313.31Anti-MRSA agent 3
CAS:<p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>Formula:C29H18BrN3O2Color and Shape:SolidMolecular weight:520.386EBOV-IN-10
CAS:<p>EBOV-IN-10 is an orally active inhibitor of the Ebola virus (EBOV) with an EC50 value of 0.19 μM.</p>Formula:C22H22N2O2SColor and Shape:SolidMolecular weight:378.49Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Formula:C17H10ClFN2Color and Shape:SolidMolecular weight:296.73LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formula:C22H19N3O2Color and Shape:SolidMolecular weight:357.41SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Formula:C21H21N5O5SColor and Shape:SolidMolecular weight:455.49Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Formula:C28H32BrN3O2Color and Shape:SolidMolecular weight:522.48SARS-CoV-2-IN-23
<p>SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].</p>Formula:C21H22N2OColor and Shape:SolidMolecular weight:318.41RCB18350
CAS:<p>RCB18350 is an antituberculosis agent and an isoxazole derivative. It demonstrates bacteriostatic properties by inhibiting the growth of Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 1.25 μg/mL. RCB18350 is effective against multi-drug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, Mycobacterium bovis BCG, and Mycobacterium avium, all of which are slow-growing mycobacteria.</p>Formula:C19H18F3N3O4SColor and Shape:SolidMolecular weight:441.424CM-728
CAS:<p>CM-728 is an oxazanonaphthoquinone that exhibits cytotoxic and antibacterial properties. It acts as a human peroxidase-1 inhibitor and serves as a source of oxidative stress affecting mitochondrial function.</p>Formula:C22H14N2O5Color and Shape:SolidMolecular weight:386.357FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Formula:C15H11ClN4O4S2Color and Shape:SolidMolecular weight:410.86C-467929
CAS:<p>C-467929 is an inhibitor of the Nsp15 endoribonuclease, exhibiting an IC50 value of 8 μM. This compound binds to the SARS-CoVNsp15 protein and is applicable for infection research.</p>Formula:C29H20N4O10Color and Shape:SolidMolecular weight:584.49Purine phosphoribosyltransferase-IN-2
<p>Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.</p>Formula:C11H15N5Na4O10P2Color and Shape:SolidMolecular weight:531.17(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Color and Shape:SolidMolecular weight:319.83FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Formula:C21H16ClF2NO2Color and Shape:SolidMolecular weight:387.81Xeruborbactam
CAS:<p>QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.</p>Formula:C10H8BFO4Purity:98%Color and Shape:SolidMolecular weight:221.98Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formula:C19H18F4O2Color and Shape:SolidMolecular weight:354.34FtsZ-IN-13
CAS:<p>FtsZ-IN-13 (Compound C11) functions as an inhibitor of the temperature-sensitive mutant Z (FtsZ), exhibiting IC50 values of 47.97 μM for FtsZSa and 34 μM for FtsZPa. It demonstrates notable antibacterial activity against Staphylococcus aureus (with a minimum inhibitory concentration of 2 μg/mL), cystic fibrosis Staphylococcus aureus clinical isolates, and methicillin-resistant Staphylococcus aureus (MRSA). FtsZ-IN-13 is applicable in research on antibiotic resistance.</p>Formula:C18H14N2O4S2Color and Shape:SolidMolecular weight:386.445Emtricitabine triphosphate
CAS:<p>Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.</p>Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19DNA crosslinker 6
CAS:<p>DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.</p>Formula:C19H21N7OColor and Shape:SolidMolecular weight:363.42Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formula:C16H23N3S2Color and Shape:SolidMolecular weight:321.5HCV-IN-7
CAS:<p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Formula:C40H48N8O6SPurity:98%Color and Shape:SolidMolecular weight:768.92Laninamivir trifluoroacetate
CAS:<p>Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.</p>Formula:C15H23F3N4O9Purity:98%Color and Shape:SolidMolecular weight:460.363OUN58101
CAS:<p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>Formula:C32H36N6O6Color and Shape:SolidMolecular weight:600.66HldA/E-IN-1
CAS:<p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>Formula:C8H17FO13P2Color and Shape:SolidMolecular weight:402.16Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Formula:C24H24FN5O7SColor and Shape:SolidMolecular weight:545.54TAN-1057C
CAS:<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Formula:C13H25N9O3Color and Shape:SolidMolecular weight:355.4KWR095
CAS:<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formula:C22H21N4O6PPurity:98%Color and Shape:SolidMolecular weight:468.40NDM-1 inhibitor-7
CAS:<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Formula:C9H10N2OS2Color and Shape:SolidMolecular weight:226.319Aurachin C
CAS:<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formula:C25H33NO2Color and Shape:SolidMolecular weight:379.535Arohynapene B
CAS:<p>Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.</p>Formula:C18H22O3Color and Shape:SolidMolecular weight:286.366FPI-1465
CAS:<p>FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>Formula:C11H18N4O7SColor and Shape:SolidMolecular weight:350.35TREX1-IN-3
CAS:<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Formula:C24H19ClN6O4Color and Shape:SolidMolecular weight:490.898HPH-15
CAS:<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Formula:C19H31N3S4Color and Shape:SolidMolecular weight:429.73SPB07935
CAS:<p>SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.</p>Formula:C22H15N5O4S2Color and Shape:SolidMolecular weight:477.516ZINC000104379474
<p>ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.</p>Formula:C27H33N3O10Color and Shape:SolidMolecular weight:559.57Antibacterial agent 262
CAS:<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Formula:C17H18F2N6O4S3Color and Shape:SolidMolecular weight:504.554Desthiazolylmethyl ritonavir
CAS:<p>Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.</p>Formula:C33H43N5O4SColor and Shape:SolidMolecular weight:605.791ATIC-IN-2
CAS:<p>ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.</p>Formula:C4H4N4O3SColor and Shape:SolidMolecular weight:188.165Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formula:C20H16F3N7O2S2Color and Shape:SolidMolecular weight:507.51Lentiginosine
CAS:<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Formula:C8H15NO2Color and Shape:SolidMolecular weight:157.21Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Formula:C25H18N2O2SColor and Shape:SolidMolecular weight:410.49Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formula:C31H34N2O7Color and Shape:SolidMolecular weight:546.61MurA-IN-6
CAS:<p>MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.</p>Formula:C22H17N3O3SColor and Shape:SolidMolecular weight:403.454SARS-CoV-2 nsp3-IN-1
<p>Compound 15c selectively inhibits SARS-CoV-2 nsp3 Mac1 with IC50 of 6.1 μM.</p>Formula:C17H15N5O2Color and Shape:SolidMolecular weight:321.33Chitinase-IN-5
<p>Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.</p>Formula:C20H21ClFN7Color and Shape:SolidMolecular weight:413.88Antibacterial agent 87
<p>Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).</p>Formula:C31H46N2O6SColor and Shape:SolidMolecular weight:574.77Antitubercular agent-22
<p>Antitubercular agent-22 combats Candida albicans (MIC: 2.34 μg/ml) and M. tuberculosis (MIC: 2 μg/ml).</p>Formula:C24H28FN5O8Color and Shape:SolidMolecular weight:533.51Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formula:C27H24FN5OColor and Shape:SolidMolecular weight:453.51MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Formula:C26H35FN16O2Purity:98%Color and Shape:SolidMolecular weight:622.66Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Formula:C35H23N5O5Color and Shape:SolidMolecular weight:593.59LN-439A
CAS:<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Formula:C24H26FN3O4Color and Shape:SolidMolecular weight:439.48bc1 Complex-IN-1
CAS:<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formula:C16H22N6O5S2Color and Shape:SolidMolecular weight:442.513Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formula:C25H24O9Color and Shape:SolidMolecular weight:468.453VPC-80051
CAS:<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Formula:C16H13F2N3OColor and Shape:SolidMolecular weight:301.291KKL-40
CAS:<p>KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.</p>Formula:C16H9F4N3O2Color and Shape:SolidMolecular weight:351.255Jun13296
CAS:<p>Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.</p>Formula:C30H34N6OColor and Shape:SolidMolecular weight:494.631Xeruborbactam isoboxil
CAS:<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formula:C15H16BFO6Color and Shape:SolidMolecular weight:322.093FG-2101
CAS:<p>FG-2101 is a selective, orally active non-hydroxamate LpxC inhibitor with an IC50 of approximately 1 nM. It demonstrates exceptional selectivity over other bacterial and human metalloproteases. FG-2101 is useful for studying infections caused by Gram-negative bacteria, including resistant strains.</p>Formula:C30H32N5O6PColor and Shape:SolidMolecular weight:589.579NRTT-IN-1
CAS:<p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>Formula:C28H24FN5O5Color and Shape:SolidMolecular weight:529.519DL-2-Aminopimelic Acid
CAS:<p>DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.</p>Formula:C7H13NO4Color and Shape:SolidMolecular weight:175.18Triazophos
CAS:<p>Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.</p>Formula:C12H16N3O3PSColor and Shape:SolidMolecular weight:313.31Pyriftalid
CAS:<p>Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.</p>Formula:C15H14N2O4SColor and Shape:SolidMolecular weight:318.35Valopicitabine
CAS:<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formula:C15H24N4O6Purity:98%Color and Shape:SolidMolecular weight:356.37NBD-14189
CAS:<p>NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).</p>Formula:C18H16F4N4O2SColor and Shape:SolidMolecular weight:428.40Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formula:C7H14N3NaO8SColor and Shape:SolidMolecular weight:323.26GSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formula:C34H43FN2O4Color and Shape:SolidMolecular weight:562.71Pibrozelesin
CAS:<p>Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.</p>Formula:C32H36BrN5O8Color and Shape:SolidMolecular weight:698.56Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Formula:C26H40N2O8Purity:98%Color and Shape:SolidMolecular weight:508.612Antibacterial agent 77
<p>Antibacterial agent 77 (compound 12) is an antibacterial agent [1].</p>Formula:C22H27N3OSColor and Shape:SolidMolecular weight:381.53(E)-Cefodizime
CAS:<p>(E)-Cefodizime ((E)-THR-221) is an antibiotic that selectively binds to penicillin-binding proteins (PBPs), inhibiting bacterial cell wall synthesis, which results in its antibacterial activity. It holds potential for research into various bacterial infections, including the prevention of preoperative infections.</p>Formula:C20H20N6O7S4Color and Shape:SolidMolecular weight:584.669Teslexivir
CAS:<p>Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.</p>Formula:C35H36BrN3O4Purity:98%Color and Shape:SolidMolecular weight:642.58DXR-IN-3
CAS:<p>DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.</p>Formula:C10H12Cl2NO5PSColor and Shape:SolidMolecular weight:360.15MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formula:C15H19N9O5S2Color and Shape:SolidMolecular weight:469.50Methyl 3-oxodecanoate
CAS:<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Formula:C11H20O3Color and Shape:SolidMolecular weight:200.275Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Formula:C19H34N8O8Color and Shape:SolidMolecular weight:502.52Deleobuvir
CAS:<p>Deleobuvir(BI207127) is an inhibitor of non-nucleoside hepatitis C virus NS5B polymerase for the treatment of hepatitis C.</p>Formula:C34H33BrN6O3Color and Shape:SolidMolecular weight:653.57PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Formula:C28H27ClN4O4Color and Shape:SolidMolecular weight:518.99Antimalarial agent 44
<p>Antimalarial agent 44 (Compound 3) is an antiparasitic agent effective against malaria. It exhibits good permeability in MDCK-MDR1 cell monolayers and has a high clearance rate in mouse liver microsomes.</p>Formula:C37H37N5O7Color and Shape:SolidMolecular weight:663.72Ac-Atovaquone
CAS:<p>Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.</p>Formula:C24H21ClO4Color and Shape:SolidMolecular weight:408.87KL-50
CAS:<p>KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.</p>Formula:C7H7FN6O2Color and Shape:SolidMolecular weight:226.172,5-Di-tert-butyl-1,4-benzoquinone
CAS:<p>2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.</p>Formula:C14H20O2Color and Shape:SolidMolecular weight:220.31SARS-CoV-2 Mpro-IN-34
<p>SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.</p>Formula:C30H37Cl2N5O3Color and Shape:SolidMolecular weight:586.55Cefamandole lithium
CAS:<p>Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.</p>Formula:C18H17LiN6O5S2Color and Shape:SolidMolecular weight:468.44Cilastatin ammonium salt
CAS:<p>Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.</p>Formula:C16H29N3O5SColor and Shape:SolidMolecular weight:375.48HIV-1 inhibitor-17
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).</p>Formula:C32H32N4O5SColor and Shape:SolidMolecular weight:584.69AB25583
CAS:<p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>Formula:C22H17ClN4O3SColor and Shape:SolidMolecular weight:452.91Neuraminidase-IN-11
<p>Neuraminidase-IN-11 (15e) inhibits H1N1 (IC50: 4.7nM), H5N1 (8.46nM), H5N8 viruses (1.5nM) selectively & potently.</p>Color and Shape:SolidHSV-TK substrate
CAS:<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Formula:C11H15N5O4Purity:98%Color and Shape:SolidMolecular weight:281.27NEU-1017
CAS:<p>NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.</p>Formula:C33H31ClFN5O3SColor and Shape:SolidMolecular weight:632.147MT0703
CAS:<p>MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.</p>Formula:C26H25N7O9S3Color and Shape:SolidMolecular weight:675.71SLU-10906
CAS:<p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>Formula:C22H21BFN5O2Color and Shape:SolidMolecular weight:417.244WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Formula:C22H22F3N5O3Purity:98%Color and Shape:SolidMolecular weight:461.44Isopyrazam
CAS:<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Formula:C20H23F2N3OColor and Shape:SolidMolecular weight:359.41Kinamycin B
CAS:<p>Kinamycin B is an antibacterial agent with anticancer activity.</p>Formula:C20H16N2O8Purity:98%Color and Shape:SolidMolecular weight:412.35Antibacterial agent 99
CAS:<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Formula:C27H27BrN2Color and Shape:SolidMolecular weight:459.42Antitumor agent-74
<p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>Formula:C26H23FN6Color and Shape:SolidMolecular weight:438.5NBTIs-IN-5
CAS:<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Formula:C24H25F3N4O2Color and Shape:SolidMolecular weight:458.48PfPKG-IN-1
<p>PfPKG-IN-1, an imidazole-based inhibitor, targets the Plasmodium falciparum cyclic guanosine monophosphate-dependent protein kinase (PfPKG).</p>Formula:C24H22ClN7OSColor and Shape:SolidMolecular weight:492Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Formula:C18H27N3O2S3Color and Shape:SolidMolecular weight:413.62Urease-IN-2
<p>Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).</p>Formula:C26H25N5O5S3Color and Shape:SolidMolecular weight:583.7β-Glucuronidase-IN-3
CAS:<p>β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric inhibitor targeting β-glucuronidase. It exhibits potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) with an IC50 of 12.9 nM. The compound exerts its inhibitory effect through reversible covalent modification of cysteine residues (Cys28, Cys443, and Cys197) on EcGUS. It is applicable in research on gut microbiota-related diseases, particularly in reducing the toxic side effects of Irinotecan and non-steroidal anti-inflammatory drugs (NSAIDs).</p>Formula:C10H7N3OSeColor and Shape:SolidMolecular weight:264.14HCV-IN-38
<p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>Formula:C22H24ClF3N4O4Color and Shape:SolidMolecular weight:500.9Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formula:C22H20Cl2N4SeColor and Shape:SolidMolecular weight:490.29SARS 3CLpro-IN-1
CAS:<p>SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.</p>Formula:C22H38N4O2Color and Shape:SolidMolecular weight:390.56SARS-CoV-2 PLpro-IN-1
CAS:<p>SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent competitive inhibitor of SARS-CoV-2 PLpro with an IC50 value of 15.06 μM and a Ki value of 22.93 μM. It inhibits the proliferation of Vero cells, exhibiting an IC50 of 7.47 μM.</p>Formula:C18H19N5OColor and Shape:SolidMolecular weight:321.376Antibiofilm agent-4
CAS:<p>Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.</p>Formula:C15H15NO3Molecular weight:257.28SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Formula:C27H30N4O5Color and Shape:SolidMolecular weight:490.55NITD-688
CAS:<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Formula:C25H32N4O3S2Color and Shape:SolidMolecular weight:500.68Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formula:C18H16Br2O2Color and Shape:SolidMolecular weight:424.13BAR-072
CAS:<p>BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.</p>Formula:C18H13N3O6Color and Shape:SolidMolecular weight:367.3125-Methylcytosine hydrochloride
CAS:<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Formula:C5H8ClN3OColor and Shape:SolidMolecular weight:161.59Nikkomycin Z
CAS:<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formula:C20H25N5O10Purity:98%Color and Shape:SolidMolecular weight:495.44MraY-IN-3
<p>MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).</p>Formula:C35H45N3O5Color and Shape:SolidMolecular weight:587.75SPR7
<p>SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).</p>Formula:C30H32ClN3O3Color and Shape:SolidMolecular weight:518.05Massarilactone H
CAS:<p>Massarilactone H, a polyketide, is a neuraminidase inhibitor, with an IC 50 of 8.18 µM .</p>Formula:C11H12O5Color and Shape:SolidMolecular weight:224.21QPX7728 methoxy acetoxy methy ester
CAS:<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Formula:C14H14BFO7Purity:98%Color and Shape:SolidMolecular weight:324.07Alpibectir
CAS:<p>Alpibectir has antibacterial activity [1].</p>Formula:C12H14F6N2O2Color and Shape:SolidMolecular weight:332.24WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Formula:C27H23N3O6Color and Shape:SolidMolecular weight:485.49Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Formula:C13H12ClN3OColor and Shape:SolidMolecular weight:261.707DHX9-IN-9
CAS:<p>DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].</p>Formula:C21H21ClFN5O3S2Color and Shape:SolidMolecular weight:510GHP-88309
CAS:<p>GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.</p>Formula:C16H11FN2OColor and Shape:SolidMolecular weight:266.27NDM-1 inhibitor-5
CAS:<p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>Formula:C24H23NO4Color and Shape:SolidMolecular weight:389.44XR8-89
CAS:<p>XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.</p>Formula:C29H36N4O2SColor and Shape:SolidMolecular weight:504.69MBL-IN-5
CAS:<p>MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.</p>Formula:C20H16ClNO3Color and Shape:SolidMolecular weight:353.80Methyl piperazine-2-carboxylate
CAS:<p>Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.</p>Formula:C6H12N2O2Color and Shape:SolidMolecular weight:144.172Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formula:C29H52INO2Color and Shape:SolidMolecular weight:573.63NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Formula:C24H21N3O5SColor and Shape:SolidMolecular weight:463.51Antileishmanial agent-4
<p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>Formula:C17H18N4O4Color and Shape:SolidMolecular weight:342.35Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formula:C14H16N2O3S2Color and Shape:SolidMolecular weight:324.42Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Formula:C17H10ClF6N3O2SColor and Shape:SolidMolecular weight:469.79PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formula:C19H18I3NO3Color and Shape:SolidMolecular weight:689.065Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Formula:C12H10F2OColor and Shape:SolidMolecular weight:208.2PFK-IN-1
CAS:<p>PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.</p>Formula:C18H15Cl2N3O4SColor and Shape:SolidMolecular weight:440.3Cap-dependent endonuclease-IN-14
CAS:<p>Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).</p>Formula:C30H23FN2O6SColor and Shape:SolidMolecular weight:558.58HBV-IN-11
CAS:<p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>Formula:C21H24ClNO6Color and Shape:SolidMolecular weight:421.87Antileishmanial agent-5
<p>Antileishmanial agent-4, a ribonucleoside analogue, targets L.infantum and T.cruzi with EC50s of 0.68 μM and 0.83 μM.</p>Formula:C17H17ClN4O4Color and Shape:SolidMolecular weight:376.79Deprodone
CAS:<p>Deprodone is an active compound that inhibits key processes such as bacterial cell wall synthesis by interacting with hydrolase and transferase proteins of methicillin-resistant Staphylococcus aureus (MRSA). It is applied in the research of MRSA infections, inflammatory skin diseases, intestinal disorders, and fatty acid metabolism disorders.</p>Formula:C21H28O4Color and Shape:SolidMolecular weight:344.44Metallo-β-lactamase-IN-13
CAS:<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Formula:C15H10F3N7O2S2Color and Shape:SolidMolecular weight:441.41BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formula:C10H7N4NaO3SPurity:98%Color and Shape:SolidMolecular weight:286.24BioA-IN-1
CAS:<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Formula:C18H17NO3SColor and Shape:SolidMolecular weight:327.397Altersolanol A
CAS:<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Formula:C16H16O8Color and Shape:SolidMolecular weight:336.29Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formula:C12H10N4SColor and Shape:SolidMolecular weight:242.3NIP-22c
CAS:<p>NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.</p>Formula:C32H39N5O6Color and Shape:SolidMolecular weight:589.68Cap-dependent endonuclease-IN-2
<p>Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.</p>Formula:C30H24FN3O7SColor and Shape:SolidMolecular weight:589.59MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formula:C23H19Cl2NO3Color and Shape:SolidMolecular weight:428.31Menoctone
CAS:<p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>Formula:C24H32O3Color and Shape:SolidMolecular weight:368.51SARS-CoV-2 Mpro-IN-32
CAS:<p>SARS-CoV-2 Mpro-IN-32 (Compound 1) is a selective inhibitor of SARS-CoV-2 MPro with an IC50 value of 230 nM. In vitro, it also inhibits the replication of various SARS-CoV-2 variants.</p>Formula:C34H32Cl2N4O9Color and Shape:SolidMolecular weight:711.54Insecticidal agent 16
CAS:<p>Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.</p>Formula:C21H13Cl2F6N5O2SColor and Shape:SolidMolecular weight:584.32SARS-CoV-2 Mpro-IN-28
CAS:<p>SARS-CoV-2 Mpro-IN-28 (Compound 1K) is an inhibitor of SARS-CoV-2 Mpro, exhibiting an EC50 of 24 μM.</p>Formula:C14H17NO3SeColor and Shape:SolidMolecular weight:326.25Ipronidazole
CAS:<p>Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.</p>Formula:C7H11N3O2Color and Shape:SolidMolecular weight:169.18Antibacterial agent 259
CAS:<p>Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.</p>Formula:C7H6ClN3O2SColor and Shape:SolidMolecular weight:231.65912(S)-HETE
CAS:<p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53BPR3P0128
CAS:<p>BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].</p>Formula:C22H18BrN3O2Color and Shape:SolidMolecular weight:436.30Neuraminidase-IN-4
<p>Neuraminidase-IN-4 inhibits neuraminidase (EC50: 1.59 μM) and has strong anti-H5N1 activity.</p>Formula:C21H20N2O6SColor and Shape:SolidMolecular weight:428.46AK-968-11563024
CAS:<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Formula:C18H13I2N9O5Color and Shape:SolidMolecular weight:689.162InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Formula:C17H18Cl2O2Color and Shape:SolidMolecular weight:325.23Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Formula:C21H23NO5Color and Shape:SolidMolecular weight:369.41PolQi1
CAS:<p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>Formula:C18H14ClF5N4O2Purity:98.97%Color and Shape:SolidMolecular weight:448.77JPL
CAS:<p>JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].</p>Formula:C19H20Cl2O2Color and Shape:SolidMolecular weight:351.27QPX7728 bis-acetoxy methyl ester
CAS:<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Formula:C15H14BFO8Purity:98%Color and Shape:SolidMolecular weight:352.08(E)-Antiviral agent 67
CAS:<p>(E)-Antiviral agent 67 (compound PC6) is a pyrazolone-based antiviral compound that exhibits inhibitory activity against RNA-dependent RNA polymerase.</p>Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.374Antifungal agent 13
CAS:<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Formula:C21H16ClF3N4OColor and Shape:SolidMolecular weight:432.83RAD51-IN-8
<p>RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.</p>Formula:C16H14Cl2FN3O2Color and Shape:SolidMolecular weight:370.21HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.674,5'-Dimethylangelicin-NHS
<p>NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity & photosensitivity.</p>Formula:C21H19NO7SColor and Shape:SolidMolecular weight:429.44N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
<p>N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].</p>Formula:C11H9FN4OColor and Shape:SolidMolecular weight:232.21Fabimycin
CAS:<p>Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.</p>Formula:C23H25ClN4O3Color and Shape:SolidMolecular weight:440.92BRN3OMe
CAS:<p>BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.</p>Formula:C7H13N3O4Color and Shape:SolidMolecular weight:203.196Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Formula:C16H35N3O2Color and Shape:SolidMolecular weight:301.47DENV-IN-6
CAS:<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Formula:C23H26ClFN4OSColor and Shape:SolidMolecular weight:461Secutrelvir
CAS:<p>Secutrelvir inhibits the 3CL protease (3CL protease), thereby exhibiting antiviral activity by preventing the replication of SARS-CoV-2.</p>Formula:C23H16Cl2F3N5O2Color and Shape:SolidMolecular weight:522.307HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Formula:C25H21N5OSColor and Shape:SolidMolecular weight:439.53ZK-316
CAS:<p>ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.</p>Formula:C27H22D6N6O3S2Color and Shape:SolidMolecular weight:554.72Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Formula:C18H23N5OSColor and Shape:SolidMolecular weight:357.47Ceftolozane TFA
CAS:<p>Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.</p>Formula:C25H31F3N12O10S2Color and Shape:SolidMolecular weight:780.71DRF-8417
CAS:<p>DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.</p>Formula:C15H17N3O5SColor and Shape:SolidMolecular weight:351.38Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formula:C31H44N2O6SColor and Shape:SolidMolecular weight:572.76Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formula:C24H26N4Se2Color and Shape:SolidMolecular weight:528.41Erythromycin B
CAS:<p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>Formula:C37H67NO12Color and Shape:SolidMolecular weight:717.93MTI013
<p>MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.</p>Formula:C24H26N6O4SColor and Shape:SolidMolecular weight:494.57MLEB-22043
<p>MLEB-22043 is a synthetic siderophore-monocyclic β-lactam conjugate which enters bacteria through TonB-dependent transport proteins utilizing its siderophore component, subsequently exerting antibacterial activity via its β-lactam portion. This compound acts as a broad-spectrum antibiotic, exhibiting significant inhibitory activity against pathogens such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa.</p>Formula:C25H25N9O11S2Color and Shape:SolidMolecular weight:691.65Bleomycin Free Base
CAS:<p>Bleomycin Free Base, a glycopeptide antibiotic, halts DNA function and treats solid tumors.</p>Formula:C55H84N17O21S3Color and Shape:SolidMolecular weight:1415.55Cap-dependent endonuclease-IN-5
CAS:<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Formula:C27H21F2N3O4S2Color and Shape:SolidMolecular weight:553.60PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Formula:C16H27N5O3SColor and Shape:SolidMolecular weight:369.48
