5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 1025 products of "5-HT Receptor"
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5-HT1A modulator 1
CAS:5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).Formula:C21H25N3O2SPurity:99.68%Color and Shape:SolidMolecular weight:383.51Pimethixene maleate
CAS:Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.Formula:C23H23NO4SPurity:99.55%Color and Shape:SolidMolecular weight:409.5Ecopipam
CAS:Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.Formula:C19H20ClNOPurity:99.68%Color and Shape:SolidMolecular weight:313.82Ricasetron
CAS:Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.Formula:C19H27N3OPurity:99.52%Color and Shape:SolidMolecular weight:313.44Anpirtoline hydrochloride
CAS:Anpirtoline hydrochloride (D-16949 hydrochloride) is a 5-HT1B receptor agonist and 5-HT3 receptor antagonist used in the study of dyskinesia.Formula:C10H14Cl2N2SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:265.20Rilapine
CAS:Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.Formula:C22H20ClN3Purity:97.76% - 99.20%Color and Shape:SolidMolecular weight:361.87Sarizotan HCl
CAS:Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.Formula:C22H22ClFN2OPurity:96%Color and Shape:SolidMolecular weight:384.87Agomelatine hydrochloride
CAS:Agomelatine HCl is a MT1/MT2 receptor agonist (Ki: 0.1-0.27 nM) and a 5-HT2C antagonist (pKi: 6.2-6.4).Formula:C15H18ClNO2Purity:99.57%Color and Shape:SolidMolecular weight:279.76Fananserin
CAS:Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).Formula:C23H24FN3O2SPurity:99.88%Color and Shape:SolidMolecular weight:425.52Ref: TM-T15270
2mg39.00€5mg52.00€1mL*10mM (DMSO)58.00€10mg77.00€25mg110.00€50mg166.00€100mg236.00€200mg349.00€cis-Urocanic acid
CAS:cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM).Formula:C6H6N2O2Purity:99.81%Color and Shape:SolidMolecular weight:138.12Repinotan
CAS:Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Formula:C21H24N2O4SPurity:99%Color and Shape:SolidMolecular weight:400.49Ensaculin
CAS:Ensaculin, a benzopyrone-piperazine compound, enhances memory, protects neurons, and may treat dementia.Formula:C26H32N2O5Purity:99.56% - 99.81%Color and Shape:SolidMolecular weight:452.54LY 272015 hydrochloride
CAS:LY 272015 hydrochloride is a 5-HT2B receptor antagonist.Formula:C21H25ClN2O2Purity:99.47%Color and Shape:SolidMolecular weight:372.89ML 10302 hydrochloride
CAS:ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3.Formula:C15H22Cl2N2O3Purity:99.99%Color and Shape:SolidMolecular weight:349.25LY266097 hydrochloride
CAS:LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression research.
Formula:C21H24Cl2N2O2Purity:98.58%Color and Shape:SolidMolecular weight:407.33ADR-851 free base
CAS:ADR-851 free base is an antagonist of the HT3 receptor.Formula:C14H18ClN3O2Purity:97.88% - 98.39%Color and Shape:SolidMolecular weight:295.778-OH-Dpat
CAS:8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.Formula:C16H25NOPurity:98%Color and Shape:SolidMolecular weight:247.38SB 699551 dihydrochloride
CAS:SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.Formula:C34H47Cl2N3OPurity:99.83%Color and Shape:SolidMolecular weight:584.66Ref: TM-T23325
1mg50.00€5mg105.00€1mL*10mM (DMSO)142.00€10mg170.00€25mg295.00€50mg424.00€100mg583.00€MM 77 dihydrochloride
CAS:MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Formula:C19H29Cl2N3O3Purity:99.91%Color and Shape:SolidMolecular weight:418.36Ref: TM-T23007
1mg86.00€5mg157.00€10mg215.00€1mL*10mM (DMSO)281.00€25mg472.00€50mg687.00€100mg938.00€500mg1,882.00€SB-215505
CAS:SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).Formula:C19H16ClN3OPurity:98.33%Color and Shape:SolidMolecular weight:337.85-HT2 antagonist 1
CAS:5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.Formula:C22H29FN4O2Purity:99.76%Color and Shape:SolidMolecular weight:400.49Ref: TM-T12597
1mg642.00€5mg1,288.00€1mL*10mM (DMSO)1,521.00€10mg1,738.00€25mg2,583.00€50mg3,484.00€100mg4,708.00€SB228357
CAS:SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.Formula:C22H17F4N3O2Purity:99.82%Color and Shape:SolidMolecular weight:431.385HT6-ligand-1
CAS:5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).Formula:C20H22BrN3O2SPurity:99.24% - 99.93%Color and Shape:SolidMolecular weight:448.38Itasetron
CAS:Itasetron, a 5-HT3 antagonist, prevents memory loss in rats and has antiemetic effects in cancer treatments.
Formula:C16H20N4O2Purity:98.58% - 99.33%Color and Shape:SolidMolecular weight:300.36RS 67333 hydrochloride
CAS:RS 67333 hydrochloride is a selective 5-HT4R partial agonist (pKi=8.7) with neuroprotective properties for Alzheimer's research.Formula:C19H30Cl2N2O2Purity:98.78%Color and Shape:SolidMolecular weight:389.36LY-2624803
CAS:LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.Formula:C22H25N3O3Purity:99.78% - 99.97%Color and Shape:SolidMolecular weight:379.45GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Formula:C23H27N3O2Purity:99.75%Color and Shape:SolidMolecular weight:377.48Lesopitron
CAS:Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.Formula:C15H21ClN6Purity:99.33% - 99.46%Color and Shape:SolidMolecular weight:320.82Ref: TM-T25672
1mg133.00€1mL*10mM (DMSO)323.00€5mg324.00€10mg477.00€25mg773.00€50mg1,063.00€100mg1,431.00€500mg2,872.00€Felcisetrag
CAS:Felcisetrag (TD-8954), an oral 5-HT4 agonist with GI prokinetic effects, has a high affinity (pKi 9.4) for h5-HT4(c) receptors.Formula:C25H37N5O3Purity:99.99%Color and Shape:SolidMolecular weight:455.59Ref: TM-T28934
1mg87.00€5mg215.00€1mL*10mM (DMSO)235.00€10mg318.00€25mg510.00€50mg692.00€100mg928.00€200mg1,251.00€PZ-1190
CAS:PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Formula:C27H30N4O2S2Purity:98%Color and Shape:SolidMolecular weight:506.68NAS-181
CAS:NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.Formula:C20H30N2O7SColor and Shape:SolidMolecular weight:442.53LY108742
CAS:LY108742 is an antagonist of 5-HT2.Formula:C21H28N2O3Purity:98%Color and Shape:SolidMolecular weight:356.46SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Formula:C25H28N4O5SColor and Shape:SolidMolecular weight:496.58Dothiepin
CAS:Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancingFormula:C19H21NSPurity:98%Color and Shape:SolidMolecular weight:295.44Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Formula:C17H23NO3Color and Shape:SolidMolecular weight:289.375-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Formula:C19H22FNO2Purity:98%Color and Shape:SolidMolecular weight:315.38UNC9994 hydrochloride
CAS:UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.Formula:C21H23Cl3N2OSColor and Shape:SolidMolecular weight:457.84Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Formula:C22H26FN3O4Color and Shape:SolidMolecular weight:415.46FPPQ
CAS:FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.Formula:C21H19FN4O2SColor and Shape:SolidMolecular weight:410.46Capeserod HCl
CAS:Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.Formula:C23H26Cl2N4O4Purity:98%Color and Shape:SolidMolecular weight:493.38Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Formula:C20H22ClF2N3OColor and Shape:SolidMolecular weight:393.86GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Formula:C17H21ClFNO2Color and Shape:SolidMolecular weight:325.81Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formula:C13H8O5Purity:96.89%Color and Shape:SolidMolecular weight:244.2LY 53857
CAS:LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.Formula:C27H36N2O7Color and Shape:SolidMolecular weight:500.592Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formula:C19H29N5O2Purity:99.35% - 99.89%Color and Shape:SolidMolecular weight:359.47Cyanopindolol fumarate
CAS:Cyanopindolol fumarate is a 5-HT receptor antagonist [1].Formula:C16H21N3O2C4H4O4Color and Shape:SolidMolecular weight:345.4Des-4-fluorobenzyl Mosapride
CAS:Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.Formula:C14H20ClN3O3Color and Shape:SolidMolecular weight:313.785-HT2A antagonist 1
CAS:5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.Formula:C26H28N4O2Purity:98%Color and Shape:SolidMolecular weight:428.53LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Formula:C28H38N2O2Color and Shape:SolidMolecular weight:434.61DU-125530
CAS:DU-125530 is a 5-HT1A receptor antagonist.Formula:C23H26ClN3O5SColor and Shape:SolidMolecular weight:491.99
