5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 940 products of "5-HT Receptor"
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5-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.04SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Formula:C25H30ClN3O3SColor and Shape:SolidMolecular weight:488.04Dehydro Aripiprazole (hydrochloride)
CAS:<p>Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.</p>Formula:C23H26Cl3N3O2Color and Shape:SolidMolecular weight:482.83Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formula:C10H13ClN2Purity:99.89%Color and Shape:SolidMolecular weight:196.68Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formula:C27H35ClFN3O11Purity:98%Color and Shape:SolidMolecular weight:632.04LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Formula:C20H22N2Purity:97.91% - 98.79%Color and Shape:SolidMolecular weight:290.4(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formula:C18H19FN2O3SPurity:98.50%Color and Shape:SoildMolecular weight:362.42Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formula:C17H19N3OColor and Shape:SolidMolecular weight:281.359Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.41isomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Formula:C20H21N3OPurity:99.92% - 99.96%Color and Shape:SoildMolecular weight:319.45-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Formula:C13H18N2OPurity:98.25%Color and Shape:SolidMolecular weight:218.29Xaliproden
CAS:<p>Xaliproden is a biochemical.</p>Formula:C24H22F3NColor and Shape:SolidMolecular weight:381.43LY-53857 free base
CAS:<p>LY-53857 free base is a bioactive chemical.</p>Formula:C23H32N2O3Color and Shape:SolidMolecular weight:384.51Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.37Cannabidiolic acid methyl ester
CAS:<p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>Formula:C23H32O4Color and Shape:SolidMolecular weight:372.5Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Formula:C25H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:503.61Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Formula:C16H18ClN3Color and Shape:SolidMolecular weight:287.79SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formula:C34H45N3OPurity:99.83%Molecular weight:511.74Nemifitide diTFA
CAS:<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Formula:C37H45F7N10O10Purity:99.78% - 99.84%Color and Shape:SolidMolecular weight:922.8LEK 8804
CAS:<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.37Triazolomethylindole-3-acetic acid
CAS:<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.26Isobutyryl-L-carnitine
CAS:<p>Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.</p>Formula:C11H21NO4Purity:98%Color and Shape:SolidMolecular weight:231.29MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formula:C22H28ClN3O2Molecular weight:401.187(R,R)-Palonosetron Hydrochloride
CAS:<p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>Formula:C19H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:332.87R 50595
CAS:<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Formula:C30H35Cl2F2N3O3Purity:98%Color and Shape:SolidMolecular weight:594.52Cinanserin hydrochloride
CAS:<p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>Formula:C20H25ClN2OSPurity:99.57%Color and Shape:SolidMolecular weight:376.94Zalospirone
CAS:<p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>Formula:C24H29N5O2Purity:98.41% - 99.82%Color and Shape:SolidMolecular weight:419.52DSP-1053
CAS:<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Formula:C26H32BrNO4Purity:98%Color and Shape:SolidMolecular weight:502.44Peptide 401
CAS:<p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>Formula:C110H192N40O24S4Purity:98%Color and Shape:SolidMolecular weight:2587.22Alverine hydrochloride
CAS:<p>Alverine hydrochloride is a parasympatholytic.</p>Formula:C20H28ClNColor and Shape:SolidMolecular weight:317.9Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formula:C18H22N2SPurity:98%Color and Shape:SolidMolecular weight:306.51,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25Serazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Formula:C22H23N3O2Purity:98.71% - 99.57%Color and Shape:SolidMolecular weight:361.44Donitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Formula:C23H26ClN5O2Purity:99.8% - 99.86%Color and Shape:SolidMolecular weight:439.94Zicronapine fumarate
CAS:<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Formula:C26H31ClN2O4Color and Shape:SolidMolecular weight:470.99Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Formula:C17H18N4OPurity:98%Color and Shape:Crystalline PowderMolecular weight:294.362-Methyl-N,N-dimethyltryptamine
CAS:<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Neocarzinostatin
CAS:<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Purity:98%Color and Shape:SolidMolecular weight:N/ASB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Formula:C28H30N4O4Purity:98.09%Color and Shape:SolidMolecular weight:486.56Cianopramine hydrochloride
CAS:<p>Cianopramine hydrochloride is a bio-active chemical.</p>Formula:C20H24ClN3Color and Shape:SolidMolecular weight:341.88AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Formula:C10H13N3OPurity:99.77%Color and Shape:SolidMolecular weight:191.23Lisuride maleate
CAS:<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Formula:C24H30N4O5Purity:99.85%Color and Shape:SolidMolecular weight:454.52BMY-14802
CAS:<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Formula:C18H22F2N4OPurity:99.84%Color and Shape:SoildMolecular weight:348.39Pellotine
CAS:<p>Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.</p>Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.2955-HT2A receptor agonist-5
CAS:<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.5Asenapine citrate
CAS:<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Formula:C23H24ClNO8Color and Shape:SolidMolecular weight:477.895-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Formula:C25H30N4O2SColor and Shape:SolidMolecular weight:450.6Minaprine
CAS:<p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>Formula:C17H22N4OPurity:98%Color and Shape:SolidMolecular weight:298.38pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Formula:C10H13Cl2NO2Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:250.12Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formula:C72H105N19O20Purity:98%Color and Shape:SolidMolecular weight:1556.72
