5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 940 products of "5-HT Receptor"
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p-MPPF
CAS:<p>p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.</p>Formula:C25H27FN4O2Purity:99.92%Color and Shape:SolidMolecular weight:434.51Brexpiprazole S-oxide
CAS:<p>Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).</p>Formula:C25H27N3O3SPurity:98%Color and Shape:SolidMolecular weight:449.57Serazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Formula:C22H23N3O2Purity:98.71% - 99.57%Color and Shape:SolidMolecular weight:361.444-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Formula:C18H30OColor and Shape:SolidMolecular weight:262.432-Methyl-N,N-dimethyltryptamine
CAS:<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Dapoxetine
CAS:<p>Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.</p>Formula:C21H23NOPurity:99.73%Color and Shape:White To Off-White Crystalline PowderMolecular weight:305.4225E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.894-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Formula:C12H18BrNO2Color and Shape:SolidMolecular weight:288.185-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Formula:C25H30N4O2SColor and Shape:SolidMolecular weight:450.6Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.37Paynantheine
CAS:<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formula:C20H21NO5Color and Shape:SolidMolecular weight:355.38AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Formula:C10H13N3OPurity:99.77%Color and Shape:SolidMolecular weight:191.235-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formula:C24H26N4O2SColor and Shape:SolidMolecular weight:434.55Tetrahydro-β-carboline
CAS:<p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C11H12N2Purity:96.31%Color and Shape:Tan SolidMolecular weight:172.22645-MeO-pyr-T
CAS:<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Formula:C15H20N2OColor and Shape:SolidMolecular weight:244.33SB 258585
CAS:<p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>Formula:C18H22IN3O3SPurity:99.8%Color and Shape:SoildMolecular weight:487.36(Iso)-Landipirdine
CAS:<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formula:C18H19FN2O3SPurity:98.50%Color and Shape:SoildMolecular weight:362.42Pellotine
CAS:<p>Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.</p>Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.295pCPA methyl ester hydrochloride
CAS:<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Formula:C10H13Cl2NO2Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:250.12Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formula:C72H105N19O20Purity:98%Color and Shape:SolidMolecular weight:1556.72Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Formula:C25H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:503.614-fluoro MBZP
CAS:<p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>Formula:C12H17FN2Color and Shape:SolidMolecular weight:208.28Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formula:C17H19N3OColor and Shape:SolidMolecular weight:281.359HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65FFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Formula:C15H13FN2OPurity:98%Color and Shape:SolidMolecular weight:256.27Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.41LY 344864 racemate
CAS:<p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>Formula:C21H22FN3OPurity:99.75%Color and Shape:SoildMolecular weight:351.42BMY-14802
CAS:<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Formula:C18H22F2N4OPurity:99.84%Color and Shape:SoildMolecular weight:348.39Donitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Formula:C23H26ClN5O2Purity:99.8% - 99.86%Color and Shape:SolidMolecular weight:439.94isomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Formula:C20H21N3OPurity:99.92% - 99.96%Color and Shape:SoildMolecular weight:319.4Alverine hydrochloride
CAS:<p>Alverine hydrochloride is a parasympatholytic.</p>Formula:C20H28ClNColor and Shape:SolidMolecular weight:317.95-methoxy-α-Ethyltryptamine
CAS:<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Formula:C13H18N2OPurity:98.25%Color and Shape:SolidMolecular weight:218.29HDAC6-IN-49
<p>HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.</p>Color and Shape:Odour Solid4-Chloromethamphetamine hydrochloride
CAS:<p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>Formula:C10H15Cl2NColor and Shape:SolidMolecular weight:220.141,8-Cineole
CAS:<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25Mosapride citrate dihydrate
CAS:<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formula:C27H35ClFN3O11Purity:98%Color and Shape:SolidMolecular weight:632.04Tiflucarbine
CAS:<p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>Formula:C16H17FN2SPurity:>99.99%Color and Shape:SolidMolecular weight:288.38LEK 8804
CAS:<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.37DOAM
CAS:<p>DOAM is an antagonist of the 5-HT2 receptor.</p>Formula:C16H27NO2Color and Shape:SolidMolecular weight:265.39R 50595
CAS:<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Formula:C30H35Cl2F2N3O3Purity:98%Color and Shape:SolidMolecular weight:594.52Eletriptan
CAS:<p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>Formula:C22H26N2O2SColor and Shape:SolidMolecular weight:382.52Desmethyl Mirtazapine (hydrochloride)
CAS:<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Formula:C16H18ClN3Color and Shape:SolidMolecular weight:287.79SB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Formula:C28H30N4O4Purity:98.09%Color and Shape:SolidMolecular weight:486.56MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formula:C22H28ClN3O2Molecular weight:401.187Minesapride
CAS:<p>Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.</p>Formula:C21H31ClN4O5Purity:99.85% - 99.88%Color and Shape:SolidMolecular weight:454.95PF-03382792
CAS:<p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>Formula:C23H32FN3O4Purity:99.64%Color and Shape:SolidMolecular weight:433.524-Hydroxy MET
CAS:<p>4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.</p>Formula:C13H18N2OColor and Shape:SolidMolecular weight:218.3Cabergoline
CAS:<p>Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.</p>Formula:C26H37N5O2Purity:97.69% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:451.6SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formula:C34H45N3OPurity:99.83%Molecular weight:511.74
