5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 1025 products of "5-HT Receptor"
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meta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formula:C17H19ClF3NOColor and Shape:SolidMolecular weight:345.79Cabergoline
CAS:Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.
Formula:C26H37N5O2Purity:97.69% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:451.6Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formula:C16H20ClNOPurity:98.97% - 99.9%Color and Shape:SoildMolecular weight:277.79Ref: TM-T67956L
1mg92.00€1mL*10mM (DMSO)197.00€5mg207.00€10mg309.00€25mg527.00€50mg755.00€100mg1,044.00€Triazolomethylindole-3-acetic acid
CAS:Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formula:C13H12N4O2Color and Shape:SolidMolecular weight:256.26Isobutyryl-L-carnitine
CAS:Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formula:C11H21NO4Purity:98%Color and Shape:SolidMolecular weight:231.29Femoxetine
CAS:Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formula:C20H25NO2Purity:99.1% - 99.35%Color and Shape:SolidMolecular weight:311.42(R,R)-Palonosetron Hydrochloride
CAS:(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormula:C19H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:332.87rac Desmethyl Citalopram Hydrochloride
CAS:rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.Formula:C19H20ClFN2OPurity:99.24%Color and Shape:SolidMolecular weight:346.835-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formula:C22H22Cl2FN3O3SColor and Shape:SolidMolecular weight:498.4Fabesetron
CAS:Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.
Formula:C18H19N3OColor and Shape:SolidMolecular weight:293.37Zalospirone
CAS:Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.Formula:C24H29N5O2Purity:98.24% - 99.82%Color and Shape:SolidMolecular weight:419.52HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formula:C35H43Cl2F2N5O4Color and Shape:SolidMolecular weight:706.65PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Color and Shape:Solid5-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formula:C24H26N4O2SColor and Shape:SolidMolecular weight:434.55Serazapine
CAS:Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Formula:C22H23N3O2Purity:98.71% - 99.57%Color and Shape:SolidMolecular weight:361.445-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formula:C15H20N2OColor and Shape:SolidMolecular weight:244.33Palonosetron N-oxide
CAS:Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.4134-Butyl-α-agarofuran
CAS:4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.Formula:C18H30OColor and Shape:SolidMolecular weight:262.432-Methyl-N,N-dimethyltryptamine
CAS:2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formula:C13H18N2Color and Shape:SolidMolecular weight:202.3Iloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formula:C23H25FN2O5Color and Shape:SolidMolecular weight:428.46AL 34662
CAS:AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormula:C10H13N3OPurity:99.97%Color and Shape:SolidMolecular weight:191.23(Iso)-Landipirdine
CAS:(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Formula:C18H19FN2O3SPurity:98.94%Color and Shape:SoildMolecular weight:362.42LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Formula:C28H39ClN2O2Color and Shape:SolidMolecular weight:471.07Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.295pCPA methyl ester hydrochloride
CAS:pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.
Formula:C10H13Cl2NO2Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:250.12Galanin (1-15) (porcine, rat)
CAS:N-terminal galanin fragment used to mediate central cardiovascular effectsFormula:C72H105N19O20Purity:98%Color and Shape:SolidMolecular weight:1556.72Quetiapine-d4 fumarate
CAS:Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.Formula:C25H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:503.61isomer-Cilansetron
CAS:isomer-Cilansetron is an isomer of Cilansetron.Formula:C20H21N3OPurity:99.92% - 99.96%Color and Shape:SoildMolecular weight:319.4Mirtazapine N-oxide
CAS:Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Formula:C17H19N3OColor and Shape:SolidMolecular weight:281.3594-fluoro MBZP
CAS:4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formula:C12H17FN2Color and Shape:SolidMolecular weight:208.28Xylamidine
CAS:Xylamidine is a biochemical.Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.41N-Desmethyl Pimavanserin
CAS:N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Formula:C24H32FN3O2Purity:98.02%Color and Shape:SolidMolecular weight:413.53FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormula:C15H13FN2OPurity:98%Color and Shape:SolidMolecular weight:256.27Lisuride maleate
CAS:Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formula:C24H30N4O5Purity:99.85%Color and Shape:SolidMolecular weight:454.52Ref: TM-T8775
1mg204.00€5mg627.00€1mL*10mM (DMSO)627.00€10mg898.00€25mg1,346.00€50mg1,745.00€100mg2,382.00€BMY-14802
CAS:BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formula:C18H22F2N4OPurity:99.84%Color and Shape:SoildMolecular weight:348.39Ref: TM-T67739
2mg35.00€5mg52.00€1mL*10mM (DMSO)58.00€10mg90.00€25mg164.00€50mg259.00€100mg383.00€200mg545.00€Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Formula:C23H24ClNO8Color and Shape:SolidMolecular weight:477.89Desmethyl Mirtazapine (hydrochloride)
CAS:Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.Formula:C16H18ClN3Color and Shape:SolidMolecular weight:287.79Oxatomide
CAS:Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Formula:C27H30N4OPurity:99.28% - 99.72%Color and Shape:White PowderMolecular weight:426.55Ref: TM-T19839
1mg35.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg114.00€25mg222.00€50mg356.00€100mg557.00€500mg1,153.00€(R)-Citalopram oxalate
CAS:(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant
Formula:C22H23FN2O5Purity:99.76%Color and Shape:White SolidMolecular weight:414.43LEK 8804
CAS:LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.Formula:C19H19N3OColor and Shape:SolidMolecular weight:305.37R 50595
CAS:R 50595 is a selective non-competitive cisapride antagonist.Formula:C30H35Cl2F2N3O3Purity:98%Color and Shape:SolidMolecular weight:594.52HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Color and Shape:Odour Solid4-Chloromethamphetamine hydrochloride
CAS:4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Formula:C10H15Cl2NColor and Shape:SolidMolecular weight:220.141,8-Cineole
CAS:Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.Formula:C10H18OPurity:97.44% - 97.44%Color and Shape:SolidMolecular weight:154.25Alverine hydrochloride
CAS:Alverine hydrochloride is a parasympatholytic.Formula:C20H28ClNColor and Shape:SolidMolecular weight:317.9Mosapride citrate dihydrate
CAS:Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.Formula:C27H35ClFN3O11Purity:98%Color and Shape:SolidMolecular weight:632.04Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormula:C16H17FN2SPurity:97.71%Color and Shape:SolidMolecular weight:288.38SB 699551
CAS:SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Formula:C34H45N3OPurity:99.83%Color and Shape:SoildMolecular weight:511.74Ref: TM-T23325L
1mg190.00€5mg471.00€10mg662.00€25mg1,036.00€50mg1,429.00€100mg1,821.00€200mg2,489.00€DOAM
CAS:DOAM is an antagonist of the 5-HT2 receptor.Formula:C16H27NO2Color and Shape:SolidMolecular weight:265.395-methoxy-α-Ethyltryptamine
CAS:5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects.
Formula:C13H18N2OPurity:98.25%Color and Shape:SolidMolecular weight:218.29
