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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 562 products of "Cyclooxygenase (COX) Inhibitors"

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  • (-)-Epicatechin

    CAS:
    <p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>
    Formula:C15H14O6
    Purity:98.55% - 98.80%
    Color and Shape:Solid
    Molecular weight:290.27
  • Licofelone

    CAS:
    <p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>
    Formula:C23H22ClNO2
    Purity:99.25%
    Color and Shape:Yellowish Solid
    Molecular weight:379.88
  • SC-236

    CAS:
    <p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>
    Formula:C16H11ClF3N3O2S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:401.79
  • Chebulagic acid

    CAS:
    <p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>
    Formula:C41H30O27
    Purity:97.82% - 99.8%
    Color and Shape:Solid
    Molecular weight:954.66
  • (-)-Epicatechin gallate

    CAS:
    <p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>
    Formula:C22H18O10
    Purity:99.16% - 99.93%
    Color and Shape:Solid
    Molecular weight:442.37
  • Flurbiprofen Axetil

    CAS:
    <p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>
    Formula:C19H19FO4
    Purity:97.58% - 98%
    Color and Shape:Solid
    Molecular weight:330.35
  • Phenidone

    CAS:
    <p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>
    Formula:C9H10N2O
    Purity:97.24%
    Color and Shape:White Solid Solid Crystalline
    Molecular weight:162.19
  • Ataquimas

    CAS:
    <p>Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.</p>
    Formula:C11H13N3O
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:203.24
  • Neochlorogenic acid

    CAS:
    <p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>
    Formula:C16H18O9
    Purity:99.12% - 99.54%
    Color and Shape:White Powder
    Molecular weight:354.31
  • Ibuprofen Lysine

    CAS:
    <p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>
    Formula:C19H32N2O4
    Purity:99.26%
    Color and Shape:Coa
    Molecular weight:352.47
  • 3-TERT-BUTYL-4-HYDROXYANISOLE

    CAS:
    <p>3-tert-Butyl-p-hydroxyanisole is an antioxidant which is produced via water chlorination.</p>
    Formula:C11H16O2
    Purity:99.65%
    Color and Shape:White Solid Waxy
    Molecular weight:180.24
  • Diclofenac Epolamine

    CAS:
    <p>Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.</p>
    Formula:C20H24Cl2N2O3
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:411.32
  • SC-560

    CAS:
    <p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>
    Formula:C17H12ClF3N2O
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:352.74
  • Prim-O-glucosylcimifugin

    CAS:
    <p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>
    Formula:C22H28O11
    Purity:98.57% - 99.92%
    Color and Shape:Solid
    Molecular weight:468.45
  • RHC 80267

    CAS:
    <p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>
    Formula:C20H34N4O4
    Purity:99.54%
    Color and Shape:White Solid
    Molecular weight:394.51
  • ETHYL CAFFEATE

    CAS:
    <p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>
    Formula:C11H12O4
    Purity:97.79%
    Color and Shape:Solid
    Molecular weight:208.21
  • Ufenamate

    CAS:
    <p>Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseases</p>
    Formula:C18H18F3NO2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:337.34
  • Veratric acid

    CAS:
    <p>Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-</p>
    Formula:C9H10O4
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:182.17
  • Indomethacin farnesil

    CAS:
    <p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>
    Formula:C34H40ClNO4
    Purity:97.29%
    Color and Shape:Solid
    Molecular weight:562.14
  • N-trans-Feruloyltyramine

    CAS:
    <p>NTF is hepatoprotective, antioxidant, inhibits COX, prevents platelet aggregation, and reduces melanin by downregulating tyrosinase.</p>
    Formula:C18H19NO4
    Purity:99.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:313.35
  • Phenethyl ferulate

    CAS:
    <p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>
    Formula:C18H18O4
    Purity:99.88% - 99.91%
    Color and Shape:Solid
    Molecular weight:298.33
  • (S)-Flurbiprofen

    CAS:
    <p>Esflurbiprofen is an inhibitor of COX-1 and COX-2.</p>
    Formula:C15H13FO2
    Purity:99.99%
    Color and Shape:White To Yellowish Crystalline Powder
    Molecular weight:244.26
  • Dehydrodiisoeugenol

    CAS:
    <p>Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.</p>
    Formula:C20H22O4
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:326.39
  • Ketorolac

    CAS:
    <p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>
    Formula:C15H13NO3
    Purity:99.68%
    Color and Shape:White Crystalline Or White Powder
    Molecular weight:255.27
  • Xanthohumol

    CAS:
    <p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>
    Formula:C21H22O5
    Purity:98.19% - 99.67%
    Color and Shape:Orange Powder
    Molecular weight:354.4
  • Loxoprofen sodium (dihydrate)

    CAS:
    <p>Loxoprofen sodium dihydrate: Non-steroidal anti-inflammatory with analgesic, antipyretic, antitumor effects; COX-1/COX-2 inhibitor. IC50: 6.5/13.5 μM.</p>
    Formula:C15H21NaO5
    Color and Shape:Solid
    Molecular weight:304.318
  • Tenidap

    CAS:
    <p>Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.</p>
    Formula:C14H9ClN2O3S
    Purity:98.56% - 99.42%
    Color and Shape:Solid
    Molecular weight:320.75
  • NF-κB/MAPK-IN-1

    CAS:
    <p>NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).</p>
    Formula:C27H27NO7
    Purity:97.03%
    Color and Shape:Solid
    Molecular weight:477.51
  • Bromfenac sodium hydrate

    CAS:
    <p>Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a NSAID with analgesic and anti-inflammatory effects.</p>
    Formula:C15H12BrNO3H2O·Na
    Purity:91.85% - 99.65%
    Color and Shape:Solid
    Molecular weight:383.17
  • Oxyphenbutazone

    CAS:
    <p>Oxyphenbutazone: Non-selective COX inhibitor, anti-inflammatory, kills dormant Mycobacterium tuberculosis.</p>
    Formula:C19H20N2O3
    Purity:99.41% - 99.88%
    Color and Shape:White To Yellowish White Crystalline Powder Solid
    Molecular weight:324.37
  • Meloxicam

    CAS:
    <p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>
    Formula:C14H13N3O4S2
    Purity:97.09% - 99.60%
    Color and Shape:Light Yellow Solid
    Molecular weight:351.40
  • Fenoprofen

    CAS:
    <p>Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, increasing ERK1/2 activation.</p>
    Formula:C15H14O3
    Purity:98.4%
    Color and Shape:Solid
    Molecular weight:242.27
  • (S)-(+)-Ibuprofen

    CAS:
    <p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>
    Formula:C13H18O2
    Purity:99.51% - 99.86%
    Color and Shape:Colourless Crystalline Solid
    Molecular weight:206.28
  • Paradol

    CAS:
    <p>Paradol, a spicy compound in ginger, offers anti-cancer, anti-inflammatory, antioxidant, and neuroprotective benefits.</p>
    Formula:C17H26O3
    Purity:98.4% - 98.98%
    Color and Shape:Solid
    Molecular weight:278.39
  • Fontolizumab

    CAS:
    <p>Fontolizumab (HuZAF) is a humanised IgG1 monoclonal anti-IFN-gamma (IFN-γ) antibody for the study of Crohn's disease.</p>
    Purity:95%
    Color and Shape:Liquid
    Molecular weight:150 (kDa)
  • Aspirin DL-lysine

    CAS:
    <p>Aspirin DL-lysine: a water-soluble, injectable NSAID that may also hinder cancer growth.</p>
    Formula:C15H22N2O6
    Color and Shape:Crystalline Solid
    Molecular weight:326.35
  • Cadonilimab

    CAS:
    <p>Cadonilimab (AK104) is a tetravalent PD-1/CTLA-4 bispecific humanised antibody that activates T cells by enhancing IL-2 and IFN-γ secretion.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Imidazole Salicylate

    CAS:
    <p>Imidazole Salicylate, a non-steroidal anti-inflammatory drug, has limited inhibitory effects on prostaglandin synthesis.</p>
    Formula:C10H10N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:206.2
  • Indometacin Farnesil

    CAS:
    Formula:C34H40ClNO4
    Purity:>98.0%(HPLC)
    Color and Shape:Light yellow to Yellow to Orange clear liquid
    Molecular weight:562.15

    Ref: 3B-I0943

    100mg
    414.00€
  • Ketorolac-d5

    CAS:
    <p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>
    Formula:C15H8D5NO3
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:260.3
  • Nepafenac-d5

    CAS:
    <p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>
    Formula:C15H14N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:259.31
  • AHR-10037

    CAS:
    <p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>
    Formula:C15H13ClN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:288.73
  • Amfenac

    CAS:
    <p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>
    Formula:C15H13NO3
    Color and Shape:Solid
    Molecular weight:255.27
  • Pelubiprofen

    CAS:
    <p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>
    Formula:C16H18O3
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:258.31
  • COX-2-IN-2

    CAS:
    <p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>
    Formula:C17H12FN3O2S
    Purity:97.62%
    Color and Shape:Solid
    Molecular weight:341.36
  • COX-2-IN-26

    CAS:
    <p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>
    Formula:C23H21N7OS3
    Color and Shape:Solid
    Molecular weight:507.65
  • Loxoprofenol-SRS tromethamine

    CAS:
    <p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>
    Formula:C19H31NO6
    Color and Shape:Solid
    Molecular weight:369.45
  • COX-2-IN-24

    CAS:
    <p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>
    Formula:C24H24BrN5O3S2
    Color and Shape:Solid
    Molecular weight:574.51
  • COX-2-IN-18

    CAS:
    <p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>
    Formula:C18H19N3O3S2
    Color and Shape:Solid
    Molecular weight:389.49
  • COX-2-IN-14

    CAS:
    <p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>
    Formula:C18H18N4O6
    Color and Shape:Solid
    Molecular weight:386.364
  • SC57666

    CAS:
    <p>SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.</p>
    Formula:C18H17FO2S
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:316.39
  • FR-188582

    CAS:
    <p>FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).</p>
    Formula:C16H13ClN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:332.8
  • Anti-inflammatory agent 56

    CAS:
    <p>Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties by</p>
    Formula:C21H15F3N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:476.43
  • COX/5-LO-IN-1

    CAS:
    <p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>
    Formula:C16H15FN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:318.37
  • MK-0703

    CAS:
    <p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>
    Formula:C17H22O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.42
  • COX-2/15-LOX-IN-1

    CAS:
    <p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>
    Formula:C21H21N7S3
    Color and Shape:Solid
    Molecular weight:467.63
  • COX-2-IN-17

    CAS:
    <p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>
    Formula:C20H23ClN6O2
    Color and Shape:Solid
    Molecular weight:414.89
  • COX-2-IN-23

    CAS:
    <p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>
    Formula:C24H25N5O3S2
    Color and Shape:Solid
    Molecular weight:495.62
  • COX-1/2-IN-3

    CAS:
    <p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>
    Formula:C14H8N2O8
    Color and Shape:Solid
    Molecular weight:332.22
  • COX-1/2-IN-1

    CAS:
    <p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>
    Formula:C15H10BrClN2O
    Color and Shape:Solid
    Molecular weight:349.61
  • K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Formula:C20H17FO2
    Color and Shape:Solid
    Molecular weight:308.35
  • Anti-inflammatory agent 8

    CAS:
    <p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>
    Formula:C18H15N5OS2
    Color and Shape:Solid
    Molecular weight:381.47
  • Apricoxib

    CAS:
    <p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>
    Formula:C19H20N2O3S
    Color and Shape:Solid
    Molecular weight:356.44
  • COX-2/sEH-IN-1

    CAS:
    <p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>
    Formula:C23H18F3N5O3S
    Color and Shape:Solid
    Molecular weight:501.48
  • Naproxen glucuronide

    CAS:
    <p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>
    Formula:C20H22O9
    Color and Shape:Solid
    Molecular weight:406.38
  • AL-8417

    CAS:
    <p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>
    Formula:C29H34O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.58
  • PD 127443

    CAS:
    <p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>
    Formula:C20H28N2O
    Color and Shape:Solid
    Molecular weight:312.45
  • COX-2-IN-32

    CAS:
    <p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>
    Formula:C25H24O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:420.45
  • Thiazolinobutazone

    CAS:
    <p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>
    Formula:C22H26N4O2S
    Color and Shape:Solid
    Molecular weight:410.53
  • ASP-6537

    CAS:
    <p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>
    Formula:C17H17N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:311.34
  • COX/5-LOX-IN-1

    CAS:
    <p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>
    Formula:C18H30O3
    Color and Shape:Solid
    Molecular weight:294.43
  • Pifoxime

    CAS:
    <p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>
    Formula:C15H20N2O3
    Color and Shape:Solid
    Molecular weight:276.33
  • COX-2-IN-16

    CAS:
    <p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>
    Formula:C19H12BrN3O2
    Color and Shape:Solid
    Molecular weight:394.22
  • COX-2/5-LOX-IN-3

    CAS:
    <p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>
    Formula:C17H16ClN3O2S
    Color and Shape:Solid
    Molecular weight:361.85
  • ATB-337

    CAS:
    <p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>
    Formula:C23H15Cl2NO2S3
    Color and Shape:Solid
    Molecular weight:504.47
  • Flosulide

    CAS:
    <p>Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.</p>
    Formula:C16H13F2NO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:353.34
  • AHR-6293

    CAS:
    <p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>
    Formula:C15H12ClNO3
    Color and Shape:Solid
    Molecular weight:289.71
  • NCX 466

    CAS:
    <p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>
    Formula:C20H24N2O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.41
  • Etoricoxib HCl

    CAS:
    <p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>
    Formula:C18H16Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:395.30
  • Lobeglitazone Sulfate

    CAS:
    <p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>
    Formula:C24H26N4O9S2
    Purity:98.69%
    Color and Shape:Solid
    Molecular weight:578.61
  • LY 25648

    CAS:
    <p>LY 25648 is an antagonist of leukotriene B4.</p>
    Formula:C19H27NO2S
    Color and Shape:Solid
    Molecular weight:333.49
  • ZXX2-77

    CAS:
    <p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>
    Formula:C13H13ClN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.77
  • LY 150310

    CAS:
    <p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>
    Formula:C13H14N2
    Color and Shape:Solid
    Molecular weight:198.26
  • PC407-ws

    CAS:
    <p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>
    Formula:C24H18F3N3Na2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:563.46
  • Isonixin

    CAS:
    <p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>
    Formula:C14H14N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:242.27
  • Prostaglandin G/H synthase 1 inhibitor

    CAS:
    <p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>
    Formula:C13H11ClN2O
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:246.69
  • Tenosal

    CAS:
    <p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>
    Formula:C12H8O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.25
  • LY 178002

    CAS:
    <p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>
    Formula:C18H25NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.46
  • L 748780

    CAS:
    <p>L 748780 is a selective inducible COX-2 inhibitor.</p>
    Formula:C19H14Cl3NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.68
  • Eicosatetraynoic acid

    CAS:
    <p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>
    Formula:C20H24O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.4
  • COX-2-IN-20

    CAS:
    <p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>
    Formula:C11H9ClFN3O2
    Color and Shape:Solid
    Molecular weight:269.66
  • Feprazone

    CAS:
    <p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>
    Formula:C20H20N2O2
    Purity:99.6% - 99.89%
    Color and Shape:Solid
    Molecular weight:320.39
  • Tilmacoxib

    CAS:
    <p>Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).</p>
    Formula:C16H19FN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.4
  • COX-2-IN-1

    CAS:
    <p>COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).</p>
    Formula:C18H14ClF3N4O2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:442.84
  • Carpro-AM1

    CAS:
    <p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>
    Formula:C21H18ClN3O
    Color and Shape:Solid
    Molecular weight:363.84
  • Enflicoxib

    CAS:
    <p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>
    Formula:C16H12F5N3O2S
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:405.34
  • Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Formula:C21H23N7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.52
  • SC58451

    CAS:
    <p>SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.</p>
    Formula:C20H19FO2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:342.43
  • COX-2-IN-21

    CAS:
    <p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>
    Formula:C21H22N6O4
    Color and Shape:Solid
    Molecular weight:422.44
  • APHS

    CAS:
    <p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>
    Formula:C15H18O2S
    Color and Shape:Solid
    Molecular weight:262.37