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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 562 products of "Cyclooxygenase (COX) Inhibitors"

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  • Ginsenoside C-K
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    Ginsenoside C-K

    CAS:
    <p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>
    Formula:C36H62O8
    Purity:99.65% - 99.97%
    Color and Shape:Solid
    Molecular weight:622.87

    Ref: TM-T3811

  • NB-598 Maleate
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    NB-598 Maleate

    CAS:
    <p>NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.</p>
    Formula:C31H35NO5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:565.74

    Ref: TM-T12199

  • Haloperidol decanoate
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    Haloperidol decanoate

    CAS:
    <p>Haloperidol decanoate (KD 16), an antipsychotic, treats schizophrenia and mood disorders as an intramuscular ester.</p>
    Formula:C31H41ClFNO3
    Purity:99.57% - 99.72%
    Color and Shape:Solid
    Molecular weight:530.11

    Ref: TM-T25487

  • syringaldehyde
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    syringaldehyde

    CAS:
    <p>Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species, moderately inhibiting COX-2 activity.</p>
    Formula:C9H10O4
    Purity:99.24%
    Color and Shape:Light Yellow-Green To Brown Crystalline Powder
    Molecular weight:182.17

    Ref: TM-T3747

  • Ibuprofen Piconol
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    Ibuprofen Piconol

    CAS:
    <p>Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.</p>
    Formula:C19H23NO2
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:297.39

    Ref: TM-T7363

  • EIPA
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    EIPA

    CAS:
    <p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>
    Formula:C11H18ClN7O
    Purity:96.62% - 99.981%
    Color and Shape:Off-White To Yellow Solid
    Molecular weight:299.76

    Ref: TM-TQ0157

  • Crocin II
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    Crocin II

    CAS:
    <p>Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.</p>
    Formula:C38H54O19
    Purity:98% - 99.00%
    Color and Shape:Solid
    Molecular weight:814.82

    Ref: TM-T3779

  • β-Elemonic Acid
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    β-Elemonic Acid

    CAS:
    <p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>
    Formula:C30H46O3
    Purity:99.61% - 99.8%
    Color and Shape:Solid
    Molecular weight:454.68

    Ref: TM-T2S0618

  • Tryptanthrin
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    Tryptanthrin

    CAS:
    <p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>
    Formula:C15H8N2O2
    Purity:99.64% - 99.94%
    Color and Shape:Solid
    Molecular weight:248.24

    Ref: TM-T7786

  • Polmacoxib
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    Polmacoxib

    CAS:
    <p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>
    Formula:C18H16FNO4S
    Purity:97.88%
    Color and Shape:Solid
    Molecular weight:361.39

    Ref: TM-T21294

  • FPL 62064
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    FPL 62064

    CAS:
    <p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>
    Formula:C16H15N3O
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:265.31

    Ref: TM-T8356

  • CAFESTOL
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    CAFESTOL

    CAS:
    <p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>
    Formula:C20H28O3
    Purity:97.06% - 99.08%
    Color and Shape:Solid
    Molecular weight:316.43

    Ref: TM-T5727

  • NS-398
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    NS-398

    CAS:
    <p>NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.</p>
    Formula:C13H18N2O5S
    Purity:99% - >99.99%
    Color and Shape:Solid
    Molecular weight:314.36

    Ref: TM-T3214

  • TFAP
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    TFAP

    CAS:
    <p>TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor</p>
    Formula:C13H10F3N3O
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:281.23

    Ref: TM-T4643

  • Revaprazan hydrochloride
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    Revaprazan hydrochloride

    CAS:
    <p>Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.</p>
    Formula:C22H24ClFN4
    Purity:99.62% - 99.91%
    Color and Shape:Solid
    Molecular weight:398.9

    Ref: TM-T2405

  • Byakangelicol
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    Byakangelicol

    CAS:
    <p>Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.</p>
    Formula:C17H16O6
    Purity:98.78% - 99.55%
    Color and Shape:Solid
    Molecular weight:316.31

    Ref: TM-T6S0077

  • Pectolinarigenin
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    Pectolinarigenin

    CAS:
    <p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>
    Formula:C17H14O6
    Purity:98.67% - 99.88%
    Color and Shape:Solid
    Molecular weight:314.29

    Ref: TM-T6S0413

  • Compound Lup-20(29)-en-3-yl acetate
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    Compound Lup-20(29)-en-3-yl acetate

    <p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>
    Formula:C32H52O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.75

    Ref: TM-TC0036

  • N-tert-butyl-α-Phenylnitrone
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    N-tert-butyl-α-Phenylnitrone

    CAS:
    <p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>
    Formula:C11H15NO
    Purity:99.46% - 99.84%
    Color and Shape:Solid
    Molecular weight:177.24

    Ref: TM-T23046

  • CAY10404
    Targetmol
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    CAY10404

    CAS:
    <p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>
    Formula:C17H12F3NO3S
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:367.34

    Ref: TM-T8656