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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 561 products of "Cyclooxygenase (COX) Inhibitors"

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  • Licofelone

    CAS:
    <p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>
    Formula:C23H22ClNO2
    Purity:99.25%
    Color and Shape:Yellowish Solid
    Molecular weight:379.88
  • Chebulagic acid

    CAS:
    <p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>
    Formula:C41H30O27
    Purity:97.82% - 99.8%
    Color and Shape:Solid
    Molecular weight:954.66
  • (-)-Epicatechin gallate

    CAS:
    <p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>
    Formula:C22H18O10
    Purity:99.16% - 99.93%
    Color and Shape:Solid
    Molecular weight:442.37
  • Flurbiprofen Axetil

    CAS:
    <p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>
    Formula:C19H19FO4
    Purity:97.58% - 98%
    Color and Shape:Solid
    Molecular weight:330.35
  • Ataquimas

    CAS:
    <p>Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.</p>
    Formula:C11H13N3O
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:203.24
  • Tepoxalin

    CAS:
    <p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>
    Formula:C20H20ClN3O3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:385.84
  • Neochlorogenic acid

    CAS:
    <p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>
    Formula:C16H18O9
    Purity:99.12% - 99.54%
    Color and Shape:White Powder
    Molecular weight:354.31
  • Ibuprofen Lysine

    CAS:
    <p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>
    Formula:C19H32N2O4
    Purity:99.26%
    Color and Shape:Coa
    Molecular weight:352.47
  • 3-TERT-BUTYL-4-HYDROXYANISOLE

    CAS:
    <p>3-tert-Butyl-p-hydroxyanisole is an antioxidant which is produced via water chlorination.</p>
    Formula:C11H16O2
    Purity:99.65%
    Color and Shape:White Solid Waxy
    Molecular weight:180.24
  • Diclofenac Epolamine

    CAS:
    <p>Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.</p>
    Formula:C20H24Cl2N2O3
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:411.32
  • SC-560

    CAS:
    <p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>
    Formula:C17H12ClF3N2O
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:352.74
  • Prim-O-glucosylcimifugin

    CAS:
    <p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>
    Formula:C22H28O11
    Purity:98.57% - 99.92%
    Color and Shape:Solid
    Molecular weight:468.45
  • RHC 80267

    CAS:
    <p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>
    Formula:C20H34N4O4
    Purity:99.54%
    Color and Shape:White Solid
    Molecular weight:394.51
  • Phenidone

    CAS:
    <p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>
    Formula:C9H10N2O
    Purity:97.24%
    Color and Shape:White Solid Solid Crystalline
    Molecular weight:162.19
  • Ufenamate

    CAS:
    <p>Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseases</p>
    Formula:C18H18F3NO2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:337.34
  • Veratric acid

    CAS:
    <p>Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-</p>
    Formula:C9H10O4
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:182.17
  • ETHYL CAFFEATE

    CAS:
    <p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>
    Formula:C11H12O4
    Purity:97.79%
    Color and Shape:Solid
    Molecular weight:208.21
  • Indomethacin farnesil

    CAS:
    <p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>
    Formula:C34H40ClNO4
    Purity:97.29%
    Color and Shape:Solid
    Molecular weight:562.14
  • N-trans-Feruloyltyramine

    CAS:
    <p>NTF is hepatoprotective, antioxidant, inhibits COX, prevents platelet aggregation, and reduces melanin by downregulating tyrosinase.</p>
    Formula:C18H19NO4
    Purity:99.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:313.35
  • Phenethyl ferulate

    CAS:
    <p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>
    Formula:C18H18O4
    Purity:99.88% - 99.91%
    Color and Shape:Solid
    Molecular weight:298.33