Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
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4-Methylamino antipyrine hydrochloride
CAS:856307-27-2
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.
Formula:
C12H16ClN3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
253.73
Ref: TM-T10152L
| 1mg | 86.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-1/2-IN-9
COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, …
Formula:
C30H20IN9O13S2
Color and Shape:
Liquid
Molecular weight:
905.57
Ref: TM-T89994
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-1-IN-2
COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a …
Formula:
C29H22FN3OS
Color and Shape:
Liquid
Molecular weight:
479.57
Ref: TM-T200220
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-2-IN-46
COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant …
Formula:
C28H19F2N3S
Color and Shape:
Liquid
Molecular weight:
467.53
Ref: TM-T89933
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
Indomethacin sodium hydrate
CAS:74252-25-8
Indomethacin sodium hydrate (Indometacin sodium hydrate) is a COX1/2 inhibitor that induces migraine headaches and …
Formula:
C19H21ClNNaO7
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
433.82
Ref: TM-T22346
| 1g | 52.00 € | ||
| 500mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
Hamaline
CAS:2411677-02-4
Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.
Formula:
C20H19ClN2O
Purity:
99.88%
Color and Shape:
Soild
Molecular weight:
338.83
Ref: TM-T60053
| 1mg | 38.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 320.00 € | ||
| 200mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
Lobuprofen
CAS:98207-12-6
Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders.
Formula:
C25H33ClN2O2
Purity:
99.09%
Color and Shape:
Liquid
Molecular weight:
428.99
Ref: TM-T68093
| 1mg | 73.00 € | ||
| 5mg | 154.00 € | ||
| 10mg | 221.00 € | ||
| 25mg | 373.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
Tetrahydroamentoflavone
CAS:48236-96-0
Tetrahydroamentoflavone is a potent XO inhibitor (IC50 = 92 nM, Ki = 982 nM) with …
Formula:
C30H22O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
542.49
Ref: TM-TN5130
| 1mg | 607.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-2-IN-49
COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of …
Ref: TM-T200429
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
Neuroprotective agent 5
Neuroprotective agent 5 (compound 28) acts as a brain-penetrating agent with anti-neuroinflammatory, antioxidant, and neuroprotective …
Ref: TM-T200770
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-2-IN-34
CAS:2788578-71-0
COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer …
Formula:
C13H11NO4
Purity:
98.08%
Color and Shape:
Soild
Molecular weight:
245.23
Ref: TM-T77618
| 1mg | 185.00 € | ||
| 5mg | 409.00 € | ||
| 10mg | 605.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,293.00 € | ||
| 100mg | 1,738.00 € | ||
| 500mg | 3,496.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
Robenacoxib
CAS:220991-32-2
Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity.
Formula:
C16H13F4NO2
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
327.27
Ref: TM-T26109
| 1mg | 69.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 149.00 € | ||
| 10mg | 235.00 € | ||
| 25mg | 455.00 € | ||
| 50mg | 723.00 € | ||
| 100mg | 938.00 € | ||
| 500mg | 1,882.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
NF157
CAS:104869-26-3
NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 …
Formula:
C49H28F2N6Na6O23S6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1437.1
Ref: TM-T16291
| 5mg | 555.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
BMP-4
CAS:1629625-47-3
BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it …
Formula:
C52H93N25O13S
Color and Shape:
Liquid
Molecular weight:
1308.52
Ref: TM-TP2930
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
Vedaprofen
CAS:71109-09-6
Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at …
Formula:
C19H22O2
Purity:
98.12% - 99.66%
Color and Shape:
Solid
Molecular weight:
282.38
Ref: TM-T36683
| 1mg | 54.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 335.00 € | ||
| 100mg | 470.00 € | ||
| 1mL*10mM (DMSO) | 127.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
β-Amyrone
CAS:638-97-1
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.
Formula:
C30H48O
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
424.7
Ref: TM-TN3500
| 1mg | 119.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 567.00 € | ||
| 25mg | 888.00 € | ||
| 50mg | 1,198.00 € | ||
| 100mg | 1,605.00 € | ||
| 500mg | 3,212.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
(Iso)-Samixogrel
CAS:133276-52-5
(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.
Formula:
C25H25ClN2O4S
Purity:
99%
Color and Shape:
Liquid
Molecular weight:
484.99
Ref: TM-T68136
| 1mg | 57.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 334.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 638.00 € | ||
| 200mg | 843.00 € |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-2-IN-35
COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory …
Formula:
C22H19NO2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
393.52
Ref: TM-T79760
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
Anti-inflammatory agent 53
Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 …
Formula:
C24H22N2O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
434.51
Ref: TM-T79599
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
COX-1/2-IN-4
COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of …
Formula:
C22H24N2O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
380.5
Ref: TM-T79592
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 31 Mar 2025
