GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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LSP1-2111
CAS:<p>LSP1-2111 is a mGlu4 receptor subtype agonist.</p>Formula:C12H17N2O9PColor and Shape:SolidMolecular weight:364.25Lu-AF11205
CAS:<p>Lu-AF11205 is a potent positive allosteric modulator (PAM) of mGlu5 receptor.</p>Formula:C17H16N2OSPurity:98%Color and Shape:SolidMolecular weight:296.39(RS)-4-Carboxyphenylglycine
CAS:<p>(RS)-4-Carboxyphenylglycine is a racemic mixture. (S)-4-Carboxyphenylglycine is a selective mGlu1α receptor antagonist.</p>Formula:C9H9NO4Purity:99.04% - >99.99%Color and Shape:SolidMolecular weight:195.17(R)-4-Carboxyphenylglycine
CAS:<p>(R)-4-Carboxyphenylglycine is a NMDA receptor antagonist.</p>Formula:C9H9NO4Purity:98%Color and Shape:SolidMolecular weight:195.17VU0652835
CAS:<p>VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).</p>Formula:C16H19N3O3SPurity:98%Color and Shape:SolidMolecular weight:333.41JNJ-55511118
CAS:<p>JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in research on chronic operant alcohol self-administration.</p>Formula:C14H8ClF3N2O2Color and Shape:SolidMolecular weight:328.67DCB
CAS:<p>DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.</p>Formula:C14H10Cl2N2Purity:99.12% - 99.9%Color and Shape:SolidMolecular weight:277.15ML337
CAS:<p>ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.</p>Formula:C21H20FNO3Purity:99.83%Color and Shape:SolidMolecular weight:353.39LY382884
CAS:<p>LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.</p>Formula:C18H23NO4Purity:98.32% - 98.71%Color and Shape:SolidMolecular weight:317.38TC-N 22A
CAS:<p>TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.</p>Formula:C14H13N5SPurity:99.95%Color and Shape:SolidMolecular weight:283.35CPPHA
CAS:<p>CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.</p>Formula:C22H15ClN2O4Purity:98.07%Color and Shape:SolidMolecular weight:406.82ML289
CAS:<p>ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.</p>Formula:C22H23NO3Purity:99.54%Color and Shape:SolidMolecular weight:349.42Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Formula:C23H23N3O3SPurity:98%Color and Shape:SolidMolecular weight:421.51VU6001376
CAS:<p>VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).</p>Formula:C18H14F2N6OSPurity:98%Color and Shape:SolidMolecular weight:400.41Ro 67-4853
CAS:<p>Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).</p>Formula:C19H19NO4Purity:98.57%Color and Shape:SolidMolecular weight:325.36VU0155041 sodium
CAS:<p>VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.</p>Formula:C14H14Cl2NNaO3Purity:98%Color and Shape:SolidMolecular weight:338.16HexylHIBO
CAS:<p>HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.</p>Formula:C12H20N2O4Purity:99.55%Color and Shape:SolidMolecular weight:256.3(S)-MCPG
CAS:<p>(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.</p>Formula:C10H11NO4Purity:98.72%Color and Shape:SolidMolecular weight:209.20DMeOB
CAS:<p>DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.</p>Formula:C16H16N2O2Purity:98.34%Color and Shape:SolidMolecular weight:268.31A-794282
CAS:<p>A-794282 is a selective antagonist of mGluR1.</p>Formula:C19H18N4OSPurity:99.87%Color and Shape:SolidMolecular weight:350.44
