GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
CPPG
CAS:<p>CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.</p>Formula:C11H14NO5PColor and Shape:SolidMolecular weight:271.21FP0429
CAS:<p>FP0429 is an agonist of mGlu4.</p>Formula:C10H12N2O7Purity:98%Color and Shape:SolidMolecular weight:272.21LY 541850
CAS:<p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>Formula:C9H13NO4Purity:98%Color and Shape:SolidMolecular weight:199.2LY3020371 hydrochloride
CAS:<p>LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.</p>Formula:C15H16ClF2NO5SColor and Shape:SolidMolecular weight:395.81PF470
CAS:<p>PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.</p>Formula:C18H16N6OColor and Shape:SolidMolecular weight:332.36Pomaglumetad methionil
CAS:<p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>Formula:C12H20N2O8S2Purity:98%Color and Shape:SolidMolecular weight:384.43YM 202074
CAS:<p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>Formula:C56H72N8O16S2Purity:98%Color and Shape:SolidMolecular weight:1177.34LY2979165
CAS:<p>LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.</p>Formula:C13H22N6O6SPurity:98.41%Color and Shape:SolidMolecular weight:390.42Eglumegad
CAS:<p>Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).</p>Formula:C8H11NO4Color and Shape:SolidMolecular weight:185.18YM-298198 hydrochloride
CAS:<p>mGlu1 receptor antagonist</p>Formula:C18H23ClN4OSPurity:98%Color and Shape:SolidMolecular weight:378.919(RS)-APICA
CAS:<p>group II metabotropic glutamate receptor antagonist</p>Formula:C10H12NO5PColor and Shape:SolidMolecular weight:257.18Eglumegad hydrochloride
<p>Eglumegad (LY354740) hydrochloride is a potent, selective agonist for group II (mGlu2/3) receptors, showing IC50 values of 5 nM for mGlu2 and 24 nM for mGlu3 receptors in transfected human cells. This compound provides neuroprotection against NMDA-induced toxicity and exhibits anxiolytic- and antipsychotic-like properties [1].</p>Formula:C8H12ClNO4Color and Shape:SolidMolecular weight:221.64VU0080241
CAS:<p>VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4).</p>Formula:C19H23N5Color and Shape:SolidMolecular weight:321.42CMPDA
CAS:<p>CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].</p>Formula:C16H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:376.53UBP1112
CAS:<p>group III mGlu receptor antagonist</p>Formula:C10H14NO5PPurity:98%Color and Shape:SolidMolecular weight:259.2
