GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 263 products for "GluR".
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FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Formula:C18H18FN5OSPurity:97.25% - 99.23%Color and Shape:White SolidMolecular weight:371.43Ref: TM-T7292
1mg34.00€2mg44.00€1mL*10mM (DMSO)62.00€5mg66.00€10mg92.00€25mg177.00€50mg268.00€100mg394.00€LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFormula:C19H22N2O2SPurity:99.34%Color and Shape:White SolidMolecular weight:342.46Ref: TM-T7706
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg86.00€25mg156.00€50mg225.00€100mg321.00€200mg447.00€CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Formula:C14H15N3OPurity:99.57% - ≥95%Color and Shape:White SolidMolecular weight:241.293-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Formula:C8H9NO4SPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:215.23Ref: TM-T3486
2mg34.00€5mg49.00€1mL*10mM (DMSO)49.00€10mg79.00€25mg145.00€50mg227.00€100mg339.00€200mg482.00€VU 0364439
CAS:VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).Formula:C18H13Cl2N3O3SPurity:97.9%Color and Shape:White SolidMolecular weight:422.29trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Formula:C7H11NO4Purity:99.98%Color and Shape:White SolidMolecular weight:173.17Ref: TM-T3484
1mg46.00€2mg59.00€1mL*10mM (DMSO)71.00€5mg94.00€10mg140.00€25mg264.00€50mg477.00€100mg692.00€VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Formula:C17H17F2NO2Purity:99% - 99.98%Color and Shape:SolidMolecular weight:305.32CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Formula:C9H4N4O4Purity:99.70%Color and Shape:SolidMolecular weight:232.15pep2-EVKI acetate(1315378-67-6 free base)
Pep2-EVKI acetate, a cell-permeable peptide, disrupts PICK1-GluR2 AMPA receptor binding.Formula:C64H99N13O21Purity:99.85%Color and Shape:White SolidMolecular weight:1386.55AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Formula:C28H28N2Purity:97.75% - 97.79%Color and Shape:SolidMolecular weight:392.54Ref: TM-T21935L
5mg48.00€1mL*10mM (DMSO)50.00€10mg71.00€25mg128.00€50mg200.00€100mg323.00€200mg450.00€JNJ-42153605
CAS:JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).Formula:C22H23F3N4Purity:97.25% - 98.57%Color and Shape:SolidMolecular weight:400.44Ref: TM-T3451
2mg34.00€5mg54.00€1mL*10mM (DMSO)55.00€10mg78.00€25mg124.00€50mg185.00€100mg263.00€200mg369.00€Lu AF21934
CAS:Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).Formula:C14H16Cl2N2O2Purity:99.01%Color and Shape:SolidMolecular weight:315.2MPEP hydrochloride
CAS:MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).Formula:C14H12ClNPurity:99.87% - >99.99%Color and Shape:SolidMolecular weight:229.7MTEP
CAS:MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.Formula:C11H8N2SColor and Shape:SolidMolecular weight:200.26Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Formula:C22H28ClN3O2Purity:98.37% - 99.85%Color and Shape:SolidMolecular weight:401.9Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Formula:C18H11F3N2O3Purity:97.57%Color and Shape:SolidMolecular weight:360.29YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Formula:C11H8ClN5O4Purity:98.23%Color and Shape:SolidMolecular weight:309.66Ref: TM-T8435
1mg73.00€5mg160.00€1mL*10mM (DMSO)170.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Formula:C12H8N4O6SPurity:97.66% - 99.93%Color and Shape:SolidMolecular weight:336.28Ref: TM-T4113
1mg38.00€2mg50.00€5mg84.00€1mL*10mM (DMSO)92.00€10mg114.00€25mg222.00€50mg334.00€100mg497.00€200mg717.00€VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Formula:C14H15Cl2NO3Purity:99.52% - 99.56%Color and Shape:SolidMolecular weight:316.18Ref: TM-T3565
2mg38.00€5mg55.00€1mL*10mM (DMSO)60.00€10mg80.00€25mg138.00€50mg178.00€100mg285.00€200mg413.00€
