GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 265 products of "GluR"
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IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Formula:C8H9ClN2O2SPurity:99.73%Color and Shape:SolidMolecular weight:232.69LY-404187
CAS:LY404187 is a positive allosteric modulator of AMPA receptorsFormula:C19H22N2O2SPurity:99.34%Color and Shape:SolidMolecular weight:342.46Ref: TM-T7706
2mg35.00€5mg52.00€1mL*10mM (DMSO)58.00€10mg90.00€25mg164.00€50mg239.00€100mg339.00€200mg472.00€HBT1
CAS:HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFormula:C16H17F3N4O2SPurity:99.52%Color and Shape:SolidMolecular weight:386.39VU-1545
CAS:VU-1545 is mGlu5 positive allosteric modulator.Formula:C22H15FN4O3Purity:98.8%Color and Shape:SolidMolecular weight:402.38VU 0357121
CAS:VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.Formula:C17H17F2NO2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:305.32Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Formula:C18H11F3N2O3Purity:97.57%Color and Shape:SolidMolecular weight:360.29VU0364770
CAS:VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGluFormula:C12H9ClN2OPurity:99.65% - >99.99%Color and Shape:SolidMolecular weight:232.67YM90K
CAS:YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.Formula:C11H8ClN5O4Purity:98.23%Color and Shape:SolidMolecular weight:309.66Ref: TM-T8435
1mg73.00€5mg160.00€1mL*10mM (DMSO)170.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€Ref: TM-T8862
1mg34.00€5mg75.00€1mL*10mM (DMSO)87.00€10mg110.00€25mg245.00€50mg363.00€100mg515.00€200mg702.00€FITM
CAS:FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).Formula:C18H18FN5OSPurity:97.25% - 99.23%Color and Shape:SolidMolecular weight:371.43Ref: TM-T7292
1mg34.00€2mg44.00€1mL*10mM (DMSO)62.00€5mg66.00€10mg92.00€25mg177.00€50mg268.00€100mg394.00€MPEP
CAS:MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.Formula:C14H11NPurity:99.54%Color and Shape:SolidMolecular weight:193.24pep2-SVKI acetate
Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.Formula:C62H97N13O20Purity:97.14%Color and Shape:SolidMolecular weight:1344.51TCN238
CAS:TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).Formula:C12H11N3Purity:99.9% - 99.92%Color and Shape:SolidMolecular weight:197.24CNQX
CAS:CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)Formula:C9H4N4O4Purity:99.70%Color and Shape:Pale Yellow SolidMolecular weight:232.15AMN082 free base
CAS:AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.Formula:C28H28N2Purity:97.75% - 97.79%Color and Shape:SolidMolecular weight:392.54Ref: TM-T21935L
5mg48.00€1mL*10mM (DMSO)50.00€10mg71.00€25mg128.00€50mg200.00€100mg323.00€200mg450.00€MTEP
CAS:MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.Formula:C11H8N2SColor and Shape:SolidMolecular weight:200.26CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Formula:C14H15N3OPurity:99.04% - ≥95%Color and Shape:Tan SolidMolecular weight:241.293-MATIDA
CAS:3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).Formula:C8H9NO4SPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:215.23Ref: TM-T3486
2mg34.00€5mg49.00€1mL*10mM (DMSO)49.00€10mg79.00€25mg145.00€50mg227.00€100mg339.00€200mg482.00€VU0155094
CAS:VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.Formula:C24H24N2O4SPurity:97.21%Color and Shape:SolidMolecular weight:436.52Ref: TM-T9011
1mg62.00€5mg110.00€1mL*10mM (DMSO)127.00€10mg161.00€25mg269.00€50mg371.00€100mg537.00€200mg710.00€Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Formula:C22H28ClN3O2Purity:98.37% - 98.75%Color and Shape:SolidMolecular weight:401.9
