GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Read more
MNI 137
CAS:946619-21-2
MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization …
Formula:
C15H9BrN4O
Purity:
97.21%
Color and Shape:
Solid
Molecular weight:
341.16
Ref: TM-T23010
| 1mg | 74.00 € | ||
| 2mg | 93.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 415.00 € | ||
| 100mg | 562.00 € | ||
| 200mg | 743.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
CMPDA
CAS:380607-77-2
CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o …
Formula:
C16H28N2O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
376.53
Ref: TM-TQ0114
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
MSOP
CAS:66515-29-5
MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM …
Formula:
C4H10NO6P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
199.1
Ref: TM-T12118
| 5mg | To inquire | ||
| 25mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
VU0652835
CAS:1848252-81-2
VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 …
Formula:
C16H19N3O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
333.41
Ref: TM-T13319
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
LY-2300559
CAS:889115-58-6
LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in …
Formula:
C26H26O6
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
434.48
Ref: TM-T27932
| 1mg | 333.00 € | ||
| 5mg | 787.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € | ||
| 500mg | 4,655.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
JNJ-55511118
CAS:2036081-86-2
JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in …
Formula:
C14H8ClF3N2O2
Color and Shape:
Solid
Molecular weight:
328.67
Ref: TM-T25558
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
DCB
CAS:6971-97-7
DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.
Formula:
C14H10Cl2N2
Purity:
99.12% - 99.9%
Color and Shape:
Solid
Molecular weight:
277.15
Ref: TM-T22711
| 5mg | 39.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 378.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
(E/Z)-SIB-1893
CAS:6266-99-5
(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.
Formula:
C14H13N
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
195.26
Ref: TM-T23353
| 5mg | 73.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 562.00 € | ||
| 500mg | 1,216.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
ML337
CAS:1443118-44-2
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.
Formula:
C21H20FNO3
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
353.39
Ref: TM-T23003
| 1mg | 35.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
LY382884
CAS:211566-75-5
LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade …
Formula:
C18H23NO4
Purity:
98.06% - 98.71%
Color and Shape:
Solid
Molecular weight:
317.38
Ref: TM-T27949
| 1mg | 710.00 € | ||
| 5mg | 1,491.00 € | ||
| 10mg | 1,882.00 € | ||
| 25mg | 2,452.00 € | ||
| 50mg | 3,022.00 € | ||
| 100mg | 4,085.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
CBiPES hydrochloride
CAS:856702-40-4
CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used …
Formula:
C21H20ClN3O2S
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
413.92
Ref: TM-T22638
| 1mg | 170.00 € | ||
| 5mg | 416.00 € | ||
| 10mg | 603.00 € | ||
| 25mg | 935.00 € | ||
| 50mg | 1,254.00 € | ||
| 100mg | 1,700.00 € | ||
| 500mg | 3,410.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
CPCCOEt
CAS:179067-99-3
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b
Formula:
C13H13NO4
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
247.25
Ref: TM-T22692
| 5mg | 52.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 313.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
S 18986
CAS:175340-20-2
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, …
Formula:
C10H12N2O2S
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
224.28
Ref: TM-T16816
| 1mg | 35.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
VU 0285683
CAS:327056-22-4
VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for …
Formula:
C14H7FN4O
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
266.23
Ref: TM-T23509
| 1mg | 42.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 335.00 € | ||
| 200mg | 455.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
TC-N 22A
CAS:1314140-00-5
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can …
Formula:
C14H13N5S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
283.35
Ref: TM-T23440
| 1mg | 120.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 309.00 € | ||
| 25mg | 520.00 € | ||
| 50mg | 748.00 € | ||
| 100mg | 1,026.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
LSN2463359
CAS:1401031-52-4
LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
Formula:
C16H15N3O
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
265.31
Ref: TM-T27854
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 383.00 € | ||
| 200mg | 545.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
CPPHA
CAS:693288-97-0
CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in …
Formula:
C22H15ClN2O4
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
406.82
Ref: TM-T10881
| 5mg | 34.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
Valiglurax
CAS:1976050-09-5
Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.
Formula:
C16H10F3N5
Purity:
97.38%
Color and Shape:
Solid
Molecular weight:
329.28
Ref: TM-T35028
| 10mg | 52.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 158.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
ML289
CAS:1382481-79-9
ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over …
Formula:
C22H23NO3
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
349.42
Ref: TM-T23000
| 5mg | 50.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 339.00 € | ||
| 200mg | 470.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
ABP688
CAS:924298-51-1
ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used …
Formula:
C15H16N2O
Purity:
97.85%
Color and Shape:
Solid
Molecular weight:
240.3
Ref: TM-T26520
| 5mg | 38.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 251.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
