GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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CFMTI
CAS:<p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>Formula:C19H16FN5OPurity:97.23%Color and Shape:SolidMolecular weight:349.36(RS)-MCPG
CAS:<p>(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.</p>Formula:C10H11NO4Purity:99.96%Color and Shape:SolidMolecular weight:209.2VU0361737
CAS:<p>VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.</p>Formula:C13H11ClN2O2Purity:99.60% - 99.85%Color and Shape:SolidMolecular weight:262.691-BCP
CAS:<p>1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.</p>Formula:C13H15NO3Purity:99.60%Color and Shape:SolidMolecular weight:233.26CX614
CAS:<p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>Formula:C13H13NO4Purity:97.37%Color and Shape:SolidMolecular weight:247.25ADX-47273
CAS:<p>ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).</p>Formula:C20H17F2N3O2Purity:97% - 99.18%Color and Shape:SolidMolecular weight:369.36AZD-8529
CAS:<p>AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.</p>Formula:C24H24F3N5O3Color and Shape:SolidMolecular weight:487.47NBQX
CAS:<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Formula:C12H8N4O6SPurity:97.66% - 99.42%Color and Shape:SolidMolecular weight:336.28XAP044
CAS:<p>XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.</p>Formula:C15H9IO4Purity:97.41%Color and Shape:SolidMolecular weight:380.13LY-404187
CAS:<p>LY404187 is a positive allosteric modulator of AMPA receptors</p>Formula:C19H22N2O2SPurity:99.34%Color and Shape:SolidMolecular weight:342.46PHCCC
CAS:<p>PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.</p>Formula:C17H14N2O3Purity:>99.99%Color and Shape:SolidMolecular weight:294.3YM90K
CAS:<p>YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.</p>Formula:C11H8ClN5O4Purity:98.23%Color and Shape:SolidMolecular weight:309.66MPEP
CAS:<p>MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.</p>Formula:C14H11NPurity:99.54%Color and Shape:SolidMolecular weight:193.243-MATIDA
CAS:<p>3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).</p>Formula:C8H9NO4SPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:215.23VU0364770
CAS:<p>VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu</p>Formula:C12H9ClN2OPurity:99.65% - >99.99%Color and Shape:SolidMolecular weight:232.67Ro0711401
CAS:<p>Ro0711401 is an agonist of mGlu1 receptor.</p>Formula:C18H11F3N2O3Purity:97.57%Color and Shape:SolidMolecular weight:360.29VU 0357121
CAS:<p>VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.</p>Formula:C17H17F2NO2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:305.32HBT1
CAS:<p>HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons</p>Formula:C16H17F3N4O2SPurity:99.52%Color and Shape:SolidMolecular weight:386.39Lu AF21934
CAS:<p>Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).</p>Formula:C14H16Cl2N2O2Purity:99.79%Color and Shape:SolidMolecular weight:315.2IDRA-21
CAS:<p>IDRA-21 is a positive AMPA receptor modulator.</p>Formula:C8H9ClN2O2SPurity:99.73%Color and Shape:SolidMolecular weight:232.69
