GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
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MFZ 10-7 hydrochloride
CAS:1779796-36-9
MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM
Formula:
C15H10ClFN2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
272.71
Ref: TM-T12025
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Methoxy-PEPy
CAS:524924-76-3
Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 …
Formula:
C13H10N2O
Purity:
99.20%
Color and Shape:
Solid
Molecular weight:
210.23
Ref: TM-T12012
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 480.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Licostinel
CAS:153504-81-5
Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.
Formula:
C8H3Cl2N3O4
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
276.03
Ref: TM-T27828
| 5mg | 59.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 413.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Biphenylindanone A
CAS:866823-73-6
Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological …
Formula:
C30H30O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
454.56
Ref: TM-T14615
| 5mg | 252.00 € | ||
| 10mg | 437.00 € | ||
| 25mg | 1,006.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
AMPA receptor modulator-2
CAS:2034181-36-5
AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent …
Formula:
C15H6F6N4OS
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
404.29
Ref: TM-T37734
| 1mg | 121.00 € | ||
| 5mg | 292.00 € | ||
| 10mg | 384.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 884.00 € | ||
| 100mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 324.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
VU6012962
CAS:2313526-86-0
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: …
Formula:
C21H19F3N4O4
Purity:
97% - 98.31%
Color and Shape:
Solid
Molecular weight:
448.4
Ref: TM-T13323
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 233.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 611.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
VU6005649
CAS:2137047-43-7
VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM …
Formula:
C16H12F5N3O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
357.28
Ref: TM-T13321
| 5mg | 41.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 258.00 € | ||
| 200mg | 367.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
VU0360172
CAS:1310012-12-4
VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = …
Formula:
C18H15FN2O
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
294.32
Ref: TM-T29126
| 1mg | 55.00 € | ||
| 5mg | 117.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 362.00 € | ||
| 50mg | 566.00 € | ||
| 100mg | 802.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
FPTQ
CAS:864863-72-9
FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM …
Formula:
C17H12FN5
Purity:
99.68% - 99.88%
Color and Shape:
Liquid
Molecular weight:
305.31
Ref: TM-T5509
| 1mg | 50.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 412.00 € | ||
| 100mg | 546.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
cis-PDA
CAS:46026-75-9
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, …
Formula:
C7H11NO4
Purity:
≥98%
Color and Shape:
White Solid
Molecular weight:
173.17
Ref: TM-T20571
| 10mg | 34.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Feb 2025
JNJ-46281222
CAS:1254980-38-5
JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.
Formula:
C23H25F3N4
Color and Shape:
Solid
Molecular weight:
414.47
Ref: TM-T15618
| 25mg | 1,327.00 € | ||
| 50mg | 1,741.00 € | ||
| 100mg | 2,986.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
L-AP4
CAS:23052-81-5
L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, …
Formula:
C4H10NO5P
Purity:
98%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
183.1
Ref: TM-T15692
| 1mg | 138.00 € | ||
| 5mg | 231.00 € | ||
| 10mg | 394.00 € | ||
| 50mg | 1,632.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Pomaglumetad methionil hydrochloride
CAS:635318-26-2
LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.
Formula:
C12H19ClN2O7S2
Purity:
99.01%
Color and Shape:
Liquid
Molecular weight:
402.87
Ref: TM-T61972
| 1mg | 197.00 € | ||
| 5mg | 502.00 € | ||
| 10mg | 723.00 € | ||
| 25mg | 1,103.00 € | ||
| 50mg | 1,504.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Philanthotoxin 74 dihydrochloride
CAS:1227301-51-0
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM …
Formula:
C24H44Cl2N4O3
Purity:
98.6%
Color and Shape:
Solid
Molecular weight:
507.54
Ref: TM-T16524
| 1mg | 51.00 € | ||
| 5mg | 144.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
LY 541850
CAS:852679-76-6
LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 …
Formula:
C9H13NO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
199.2
Ref: TM-T11906
| 25mg | 2,384.00 € | ||
| 50mg | 3,161.00 € | ||
| 100mg | 4,302.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
LY3020371 hydrochloride
CAS:1377615-44-5
LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.
Formula:
C15H16ClF2NO5S
Color and Shape:
Solid
Molecular weight:
395.81
Ref: TM-T11911
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Mar 2025
Pomaglumetad methionil
CAS:956385-05-0
Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor …
Formula:
C12H20N2O8S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
384.43
Ref: TM-T12520
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Mar 2025
LY2979165
CAS:1311385-32-6
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies …
Formula:
C13H22N6O6S
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
390.42
Ref: TM-T15812
| 1mg | 73.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 545.00 € | ||
| 100mg | 777.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
