
GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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MAP4
CAS:<p>metabotropic glutamate receptor modulator</p>Formula:C5H12NO5PPurity:98%Color and Shape:White SolidMolecular weight:197.13GRN-529
CAS:<p>GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.</p>Formula:C22H15F2N3O2Purity:98%Color and Shape:SolidMolecular weight:391.37DFMTI
CAS:<p>DFMTI can completely block the rmGlu1 L757V glutamate response.</p>Formula:C20H18F2N4OColor and Shape:SolidMolecular weight:368.38Z-Cyclopentyl-AP4
CAS:<p>Group III mGlu receptor agonist</p>Formula:C6H12NO5PPurity:98%Color and Shape:SolidMolecular weight:209.14LY456066
CAS:<p>LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.</p>Formula:C19H23N3OSPurity:98%Color and Shape:SolidMolecular weight:341.47JNJ-40068782
CAS:<p>JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.</p>Formula:C21H23N3OPurity:98%Color and Shape:SolidMolecular weight:333.43TASP0433864
CAS:<p>TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.</p>Formula:C18H23N3O3Purity:98%Color and Shape:SolidMolecular weight:329.39(S)-3,5-DHPG
CAS:<p>group I mGlu receptor agonist</p>Formula:C8H9NO4Purity:98%Color and Shape:SolidMolecular weight:183.16HTL14242
CAS:<p>HTL14242 is a mGlu5 Negative Allosteric Modulator.</p>Formula:C16H8ClFN4Color and Shape:SolidMolecular weight:310.71(RS)-PPG
CAS:<p>(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.</p>Formula:C8H10NO5PPurity:98%Color and Shape:SolidMolecular weight:231.14VU0431316
CAS:<p>VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.</p>Formula:C14H9ClN6O2Purity:98%Color and Shape:SolidMolecular weight:328.71DCG-IV
CAS:<p>DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.</p>Formula:C7H9NO6Purity:98%Color and Shape:SolidMolecular weight:203.15VU0410425
CAS:<p>VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.</p>Formula:C19H16ClN3O3Purity:98%Color and Shape:SolidMolecular weight:369.8AZ12216052
CAS:<p>AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Formula:C19H22BrNOSPurity:99.29%Color and Shape:SolidMolecular weight:392.35LY487379 hydrochloride
CAS:<p>Positive allosteric modulator of mGlu2 receptors</p>Formula:C21H20ClF3N2O4SPurity:98%Color and Shape:SolidMolecular weight:488.91VU0361747
CAS:<p>VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).</p>Formula:C19H17FN2O2Color and Shape:SolidMolecular weight:324.35Auglurant
CAS:<p>Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.</p>Formula:C16H12FN5O2Color and Shape:SolidMolecular weight:325.3Desmethyl-YM 298198
CAS:<p>mGlu1-selective antagonist</p>Formula:C17H21ClN4OSPurity:98%Color and Shape:SolidMolecular weight:364.89Foliglurax monohydrochloride
CAS:<p>Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.</p>Formula:C23H24ClN3O3SColor and Shape:SolidMolecular weight:457.97L-CCG-l
CAS:<p>group II metabotropic glutamate receptor agonist</p>Formula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14
