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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • NKH477
    Targetmol
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    NKH477

    CAS:
    <p>NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.</p>
    Formula:C27H44ClNO8
    Purity:98% - 98%
    Color and Shape:Solid
    Molecular weight:546.09

    Ref: TM-T16332

  • Cevimeline
    Targetmol
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    Cevimeline

    CAS:
    <p>Cevimeline: muscarinic agonist, treats dry mouth &amp; Sjögren's, boosts saliva post-cancer radiotherapy.</p>
    Formula:C10H17NOS
    Color and Shape:Off-White Solid
    Molecular weight:199.31

    Ref: TM-T21119

  • Pirmenol hydrochloride
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    Pirmenol hydrochloride

    CAS:
    <p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>
    Formula:C22H31ClN2O
    Color and Shape:Solid
    Molecular weight:374.95

    Ref: TM-T61529

  • (±)-Darifenacin
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    (±)-Darifenacin

    CAS:
    <p>(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.</p>
    Formula:C28H30N2O2
    Color and Shape:Solid
    Molecular weight:426.55

    Ref: TM-T12680

  • VU0467485
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    VU0467485

    CAS:
    <p>VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.</p>
    Formula:C17H17FN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.41

    Ref: TM-T17245

  • Clorprenaline
    Targetmol
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    Clorprenaline

    CAS:
    <p>Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.</p>
    Formula:C11H16ClNO
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:213.7

    Ref: TM-T60261

  • (S)-(+)-Dimethindene maleate
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    (S)-(+)-Dimethindene maleate

    CAS:
    <p>(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1 receptors</p>
    Formula:C24H28N2O4
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:408.49

    Ref: TM-T23297

  • Tebanicline dihydrochloride
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    Tebanicline dihydrochloride

    CAS:
    <p>Tebanicline dihydrochloride: oral analgesic, nAChR modulator, Ki=37 pM at α4β2 receptors, inhibits cytisine binding.</p>
    Formula:C9H13Cl3N2O
    Color and Shape:Solid
    Molecular weight:271.57

    Ref: TM-T60474

  • Sabcomeline hydrochloride
    Targetmol
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    Sabcomeline hydrochloride

    CAS:
    <p>Sabcomeline is a selective M1 receptor partial agonist.</p>
    Formula:C10H16ClN3O
    Color and Shape:Solid
    Molecular weight:229.71

    Ref: TM-T28654

  • Fesoterodine L-mandelate
    Targetmol
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    Fesoterodine L-mandelate

    CAS:
    <p>Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).</p>
    Formula:C34H45NO6
    Color and Shape:Solid
    Molecular weight:563.735

    Ref: TM-T11275

  • DL-Cystine
    Targetmol
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    DL-Cystine

    CAS:
    <p>DL-Cystine is a cysteine derivative that inhibits endothelial cell proliferation by regulating TGFβ1. a GPR inhibitor and nAChR agonist .</p>
    Formula:C6H12N2O4S2
    Color and Shape:Solid
    Molecular weight:240.3

    Ref: TM-T66846

  • NS3861 fumarate
    Targetmol
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    NS3861 fumarate

    CAS:
    <p>NS3861 fumarate, a partial α3β4 nAChR agonist, binds α3β2, α4β4, α4β2 with Ki values of 0.62, 25, 7.8, 55 nM.</p>
    Formula:C16H18BrNO4S
    Color and Shape:Solid
    Molecular weight:400.29

    Ref: TM-T9450

  • N6-Methyladenosine 5'-monophosphate disodium salt
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    N6-Methyladenosine 5'-monophosphate disodium salt

    CAS:
    <p>N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.</p>
    Formula:C11H14N5Na2O7P
    Purity:99.36% - 99.36%
    Color and Shape:Solid
    Molecular weight:405.21

    Ref: TM-T12162

  • Tebanicline hydrochloride
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    Tebanicline hydrochloride

    CAS:
    <p>Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.</p>
    Formula:C9H12Cl2N2O
    Purity:91.74% - 98.71%
    Color and Shape:Solid
    Molecular weight:235.11

    Ref: TM-T3720

  • VU0119498
    Targetmol
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    VU0119498

    CAS:
    <p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>
    Formula:C15H10BrNO2
    Purity:97.56%
    Color and Shape:Solid
    Molecular weight:316.15

    Ref: TM-T8224

  • VU0152100
    Targetmol
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    VU0152100

    CAS:
    <p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>
    Formula:C18H19N3O2S
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:341.43

    Ref: TM-T17238

  • Nitrobenzylthioinosine
    Targetmol
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    Nitrobenzylthioinosine

    CAS:
    <p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>
    Formula:C17H17N5O6S
    Purity:99.69% - 99.74%
    Color and Shape:Off-White Solid
    Molecular weight:419.41

    Ref: TM-T8551

  • NS9283
    Targetmol
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    NS9283

    CAS:
    <p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>
    Formula:C14H8N4O
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:248.24

    Ref: TM-T28199

  • Ethyl (triphenylphosphoranylidene) acetate
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    Ethyl (triphenylphosphoranylidene) acetate

    CAS:
    <p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>
    Formula:C22H21O2P
    Purity:97.985%
    Color and Shape:White Or Slight Yellow Powder
    Molecular weight:348.37

    Ref: TM-T22329

  • ML380
    Targetmol
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    ML380

    CAS:
    <p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>
    Formula:C23H25F3N4O3S
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:494.53

    Ref: TM-T28069