AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formula:C24H38Br2N2Purity:98.72%Color and Shape:SolidMolecular weight:514.38Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.23NNC 11-1607
CAS:NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.Formula:C30H32N6O2S2Color and Shape:SolidMolecular weight:572.74M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurity:99.14%Color and Shape:SolidMolecular weight:290.38(R)-Dinotefuran
CAS:(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.Formula:C7H14N4O3Color and Shape:SolidMolecular weight:202.21TC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43Ebiratide TFA
Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.Formula:C48H73N11O10S·xC2HF3O2Color and Shape:SolidMolecular weight:996.23 (free base)Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formula:C18H23N6O14P3SColor and Shape:SolidMolecular weight:672.39Navafenterol saccharinate
CAS:AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).Formula:C45H47N7O9S3Color and Shape:SolidMolecular weight:926.09α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFormula:C83H125N27O27S5Purity:98%Color and Shape:SolidMolecular weight:2093.37DSPE-PEG5000-RVG29
DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.Color and Shape:Odour SolidHydroxybupropion
CAS:Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formula:C13H18ClNO2Purity:99.73%Color and Shape:Off-White SolidMolecular weight:255.74Ref: TM-T11588
1mg89.00€5mg204.00€10mg331.00€25mg545.00€50mg777.00€100mg1,063.00€1mL*10mM (DMSO)232.00€Aceclidine (hydrochloride)
CAS:agonist of muscarinic receptorsFormula:C9H16ClNO2Purity:98%Color and Shape:SolidMolecular weight:205.68Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Color and Shape:SolidMolecular weight:160.22Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Color and Shape:SolidMolecular weight:256.09Perindoprilat
CAS:Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.Formula:C17H28N2O5Purity:99.21%Color and Shape:SolidMolecular weight:340.41(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Formula:C22H32ClNO2Color and Shape:SolidMolecular weight:377.955-Hydroxymethyl tolterodine formate
CAS:5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.Formula:C23H33NO4Color and Shape:SolidMolecular weight:387.51trans-Cevimeline hydrochloride
CAS:AF 102A hydrochloride is a biochemical.Formula:C10H18ClNOSColor and Shape:SolidMolecular weight:235.77nAChR modulator-1
CAS:nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66Lu AE51090
CAS:Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.Formula:C24H29N3O3Purity:99.57%Color and Shape:SolidMolecular weight:407.51sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColor and Shape:SolidMolecular weight:193.25G-Protein antagonist peptide
CAS:Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.Formula:C57H64N12O9SPurity:98%Color and Shape:SolidMolecular weight:1093.27β2AR/M-receptor agonist-1
CAS:β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor andFormula:C43H56BrN3O7Color and Shape:SolidMolecular weight:806.82Soclenicant
CAS:Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormula:C24H26N4O3Purity:99.57%Color and Shape:SoildMolecular weight:418.49M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.45LAS190792
CAS:LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.Formula:C39H43ClN4O9S2Color and Shape:SolidMolecular weight:811.36TIP 39, Tuberoinfundibular Neuropeptide
CAS:TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.Formula:C202H325N61O54SPurity:98%Color and Shape:SolidMolecular weight:4504.2Muscarine
CAS:Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Formula:C9H20NO2Purity:98%Color and Shape:SolidMolecular weight:174.26nAChR agonist 2
CAS:Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,Formula:C11H16N2Color and Shape:SolidMolecular weight:176.263Rocuronium
CAS:Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.Formula:C32H53N2O4Purity:98%Color and Shape:SolidMolecular weight:529.77Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.63% - 99.96%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg120.00€2mg170.00€5mg289.00€10mg467.00€25mg835.00€50mg1,134.00€100mg1,504.00€1mL*10mM (DMSO)319.00€N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purity:99.65%Color and Shape:SolidMolecular weight:136.19R-(+)-Cotinine
CAS:R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.Formula:C10H12N2OColor and Shape:SolidMolecular weight:176.22[Ala2,8,9,11,19,22,24,25,27,28]-VIP
CAS:[Ala2,8,9,11,19,22,24,25,27,28]-VIP can be used for related research in the field of life sciences. Its product number is T36637 and CAS number is 866552-34-3.Formula:C131H219N41O33SColor and Shape:SolidMolecular weight:2928.51Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Formula:C21H32BrNO2Color and Shape:SolidMolecular weight:410.39TDI-10229
CAS:TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.Formula:C16H16ClN5Purity:99.85% - 99.89%Color and Shape:SoildMolecular weight:313.78Ref: TM-T64355
1mg39.00€5mg157.00€10mg224.00€25mg409.00€50mg615.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)167.00€BTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Formula:C28H52N2O4Purity:98.1%Color and Shape:SolidMolecular weight:480.72Doxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Formula:C56H78ClN2O16Purity:98%Color and Shape:SolidMolecular weight:1070.69VU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Formula:C23H27F3N4OColor and Shape:SolidMolecular weight:432.491M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.Formula:C38H41Cl2N3O8SColor and Shape:SolidMolecular weight:770.72DSPE-PEG2000-RVG29
DSPE-PEG2000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and can traverse the BBB.Color and Shape:Odour Solid(rel)-Asperparaline A
CAS:Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.
Formula:C20H29N3O3Color and Shape:SolidMolecular weight:359.47Rivanicline 2HCl
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.Formula:C10H16Cl2N2Purity:99.4%Color and Shape:SoildMolecular weight:235.15Ref: TM-T12738L1
1mg34.00€5mg71.00€10mg100.00€25mg234.00€50mg420.00€100mg617.00€1mL*10mM (DMSO)110.00€Ebiratide
CAS:Ebiratide is an analog of ACTH 4-9.Formula:C48H73N11O10SPurity:98%Color and Shape:SolidMolecular weight:996.23Albanin A
Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.Formula:C20H18O6Color and Shape:SolidMolecular weight:354.358(-)-Coclaurine hydrochloride
CAS:(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.Formula:C17H20ClNO3Purity:99.07%Color and Shape:SoildMolecular weight:321.8Ref: TM-TN1519L
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)249.00€Lupanine perchlorate
CAS:Lupanine perchlorate is a bioactive chemical.Formula:C15H25ClN2O5Color and Shape:SolidMolecular weight:348.82AC1-IN-1
CAS:AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
Formula:C18H18FN5O2Purity:99.89%Color and Shape:SolidMolecular weight:355.37SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formula:C13H19NOSPurity:99.79%Color and Shape:SoildMolecular weight:237.36
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