AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
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BNC210
CAS:<p>BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.</p>Formula:C17H23N3O3Purity:97.05% - >99.99%Color and Shape:SolidMolecular weight:317.38Prifinium bromide
CAS:<p>Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.</p>Formula:C22H28BrNPurity:97.99%Color and Shape:SolidMolecular weight:386.37Nor-benzetimide
CAS:<p>Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.</p>Formula:C16H20N2O2Purity:98.63%Color and Shape:SolidMolecular weight:272.34NS 1738
CAS:<p>NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)</p>Formula:C14H9Cl2F3N2O2Purity:99.11%Color and Shape:SolidMolecular weight:365.13Cyclodrine hydrochloride
CAS:<p>Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study of</p>Formula:C19H30ClNO3Purity:98.59%Color and Shape:SolidMolecular weight:355.9Pozanicline dihydrochloride
CAS:<p>Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)</p>Formula:C11H18Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:265.18(-)-(S)-B-973B
CAS:<p>(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.</p>Formula:C24H26F2N6OPurity:99.52%Color and Shape:SolidMolecular weight:452.5ST034307
CAS:<p>ST034307 is an effective and selective inhibitor of adenylyl cyclase 1 (IC50: 2.3 μM).</p>Formula:C10H4Cl4O2Purity:99.28%Color and Shape:SolidMolecular weight:297.95Oxyphenonium bromide
CAS:<p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>Formula:C21H34BrNO3Purity:98.96%Color and Shape:SolidMolecular weight:428.404Umeclidinium bromide
CAS:<p>Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.</p>Formula:C29H34BrNO2Purity:98.4% - 99.89%Color and Shape:SolidMolecular weight:508.49Nitrobenzylthioinosine
CAS:<p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>Formula:C17H17N5O6SPurity:99.69% - 99.74%Color and Shape:Off-White SolidMolecular weight:419.41PHA 568487 free base
CAS:<p>PHA 568487 free base, an α7 nicotinic receptor agonist, designed to reduce bioactivation and improve in vivo tolerability.</p>Formula:C16H20N2O3Purity:99.74%Color and Shape:SolidMolecular weight:288.34mAChR-IN-1 hydrochloride
CAS:<p>mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.</p>Formula:C23H26ClIN2O2Purity:99.87%Color and Shape:SolidMolecular weight:524.82NS9283
CAS:<p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>Formula:C14H8N4OPurity:99.12%Color and Shape:SolidMolecular weight:248.24PNU-120596
CAS:<p>PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.</p>Formula:C13H14ClN3O4Purity:99.82%Color and Shape:SolidMolecular weight:311.72MC-Val-Cit-PABC-PNP
CAS:<p>MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.</p>Formula:C35H43N7O11Purity:97.2% - 98.055%Color and Shape:SolidMolecular weight:737.76Ethyl (triphenylphosphoranylidene) acetate
CAS:<p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>Formula:C22H21O2PPurity:97.985%Color and Shape:White Or Slight Yellow PowderMolecular weight:348.37Blarcamesine
CAS:<p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>Formula:C19H23NOPurity:99.87%Color and Shape:SolidMolecular weight:281.39Encenicline hydrochloride
CAS:<p>Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).</p>Formula:C16H17ClN2OS·HClPurity:98.34% - 99.85%Color and Shape:SolidMolecular weight:357.3(S)-UFR2709
CAS:<p>(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.</p>Formula:C13H17NO2Color and Shape:SolidMolecular weight:219.284Mc-Val-Ala-PAB
CAS:<p>Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).</p>Formula:C25H34N4O6Purity:98.34% - 99.24%Color and Shape:SolidMolecular weight:486.56Pipecuronium bromide
CAS:<p>Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.</p>Formula:C35H62Br2N4O4Purity:>99.99%Color and Shape:PowderMolecular weight:762.7Velufenacin
CAS:<p>Velufenacin is an antagonist of muscarinic receptor[1].</p>Formula:C19H20ClFN2O2Purity:99.65%Color and Shape:SolidMolecular weight:362.83Pentoxyverine
CAS:<p>Pentoxyverine (Carbetapentan) is an orally available cough suppressant, an antagonist of muscarinic receptor M1 and an agonist of the σ1 receptor.</p>Formula:C20H31NO3Purity:97.11%Color and Shape:SolidMolecular weight:333.47Mepenzolate Bromide
CAS:<p>Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions.</p>Formula:C21H26BrNO3Purity:95.73% - 99.21%Color and Shape:SolidMolecular weight:420.34AF-710B
CAS:<p>AF710B is an enantiomer of AF710. AF-710B is also a sigma and M1 muscarinic receptors agonist.</p>Formula:C20H27N3OSPurity:98.62% - 99.89%Color and Shape:SolidMolecular weight:357.51Monepantel
CAS:<p>Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.</p>Formula:C20H13F6N3O2SPurity:99.83%Color and Shape:White PowderMolecular weight:473.39Xanomeline tartrate
CAS:<p>Xanomeline tartrate (LY 246708 tartrate) 是 M1和 M4 mAChR 激动剂，具有抗精神病样活性，可改善认知，可用于研究精神分裂症和阿尔茨海默病。</p>Formula:C18H29N3O7SPurity:99.19%Color and Shape:SolidMolecular weight:431.5Varenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26Pyrantel
CAS:<p>Pyrantel: Nicotinic agonist; causes spastic paralysis in nematodes by depolarizing block.</p>Formula:C11H14N2SPurity:98%Color and Shape:Crystals From Methanol Yellowish Crystalline PowderMolecular weight:206.31Atropine hydrobromide
CAS:<p>Atropine hydrobromide is a biochemical.</p>Formula:C17H24BrNO3Color and Shape:SolidMolecular weight:370.28Flavoxate
CAS:<p>Flavoxate is an anticholinergic with antimuscarinic effects.</p>Formula:C24H25NO4Color and Shape:SolidMolecular weight:391.46Anatabine dicitrate
<p>Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.</p>Formula:C22H28N2O14Purity:98%Color and Shape:SolidMolecular weight:544.46Oxantel
CAS:<p>Oxantel is a fumarate reductase inhibitor with anthelmintic activity.</p>Formula:C13H16N2OPurity:98%Color and Shape:SolidMolecular weight:216.28Biperiden lactate
CAS:<p>Biperiden lactate is a biochemical.</p>Formula:C24H35NO4Color and Shape:SolidMolecular weight:401.54Catestatin
CAS:<p>Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.</p>Formula:C107H173N37O26SPurity:98%Color and Shape:SolidMolecular weight:2425.84VU0029767
CAS:<p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>Formula:C21H21N3O3Color and Shape:SolidMolecular weight:363.41Diphenidol
CAS:<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Formula:C21H27NOColor and Shape:Needles From Petroleum Ether SolidMolecular weight:309.45Azacyclonol hydrochloride
CAS:<p>Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.</p>Formula:C18H22ClNOColor and Shape:Off White Crystalline PowderMolecular weight:303.83Dianicline dihydrochloride
CAS:<p>Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.</p>Formula:C13H16N2OPurity:98%Color and Shape:SolidMolecular weight:216.28Aprofene
CAS:<p>Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.</p>Formula:C21H27NO2Color and Shape:SolidMolecular weight:325.44Sulindac sulfide
CAS:<p>Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.</p>Formula:C20H17FO2SPurity:99.35%Color and Shape:SolidMolecular weight:340.41N-0861 racemate
CAS:<p>N-0861 racemate is the racemate of N-0861.</p>Formula:C13H17N5Purity:98%Color and Shape:SolidMolecular weight:243.31Sulfoxaflor
CAS:<p>Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.</p>Formula:C10H10F3N3OSPurity:99.56%Color and Shape:SolidMolecular weight:277.27Sch412348
CAS:<p>Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, >1000-fold selectivity vs. other adenosine receptors.</p>Formula:C22H21F2N9OPurity:98%Color and Shape:SolidMolecular weight:465.46SR 16584
CAS:<p>α3β4 nAChR antagonist</p>Formula:C17H22N2OPurity:99.84%Color and Shape:SolidMolecular weight:270.37Tarafenacin
CAS:<p>Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>Formula:C21H20F4N2O2Purity:98%Color and Shape:SolidMolecular weight:408.39Meseclazone
CAS:<p>Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.</p>Formula:C11H10ClNO3Purity:98%Color and Shape:SolidMolecular weight:239.654-DAMP
CAS:<p>4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.</p>Formula:C21H26INO2Purity:98%Color and Shape:SolidMolecular weight:451.34mAChr-in-1
CAS:<p>mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).</p>Formula:C23H25IN2O2Purity:98%Color and Shape:SolidMolecular weight:488.36
