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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 575 products of "AChR"

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  • Encenicline
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    Encenicline

    CAS:
    <p>Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.</p>
    Formula:C16H17ClN2OS
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:320.84

    Ref: TM-T7193

  • Propiverine
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    Propiverine

    CAS:
    <p>Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.</p>
    Formula:C23H29NO3
    Color and Shape:Solid
    Molecular weight:367.48

    Ref: TM-T61438

  • JHU37160
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    JHU37160

    CAS:
    JHU37160 is a DREADD agonist with Ki of 1.9 nM for hM3Dq, 3.6 nM for hM4Di, and EC50 of 18.5 nM (hM3Dq), 0.2 nM (hM4Di) in HEK-293 cell assays.
    Formula:C19H20ClFN4
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:358.84

    Ref: TM-T9018

  • OXOMEMAZINE
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    OXOMEMAZINE

    CAS:
    <p>Oxomemazine: a phenothiazine antihistamine H1-blocker with strong antimuscarinic and selective M1 antagonist properties, used in cough research.</p>
    Formula:C18H22N2O2S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:330.44

    Ref: TM-T9353

  • Mecamylamine
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    Mecamylamine

    CAS:
    <p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>
    Formula:C11H21N
    Color and Shape:Solid
    Molecular weight:167.29

    Ref: TM-T69019

  • Methylbenactyzium Bromide
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    Methylbenactyzium Bromide

    CAS:
    <p>Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione.</p>
    Formula:C21H28BrNO3
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:422.36

    Ref: TM-T6744

  • Solifenacin hydrochloride
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    Solifenacin hydrochloride

    CAS:
    <p>Solifenacin Hcl is a muscarinic receptor antagonist.</p>
    Formula:C23H27ClN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.93

    Ref: TM-T23379

  • Donepezil Hydrochloride
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    Donepezil Hydrochloride

    CAS:
    <p>Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).</p>
    Formula:C24H29NO3·HCl
    Purity:99.55% - 99.8%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:415.96

    Ref: TM-T6478

  • Isopropamide Iodide
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    Isopropamide Iodide

    CAS:
    <p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>
    Formula:C23H33IN2O
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:480.43

    Ref: TM-T5051

  • SQ22536
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    SQ22536

    CAS:
    <p>SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.</p>
    Formula:C9H11N5O
    Purity:99.18%
    Color and Shape:Off-White Solid
    Molecular weight:205.22

    Ref: TM-T2172

  • ML380
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    ML380

    CAS:
    <p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>
    Formula:C23H25F3N4O3S
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:494.53

    Ref: TM-T28069

  • VU0467154
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    VU0467154

    CAS:
    <p>VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.</p>
    Formula:C17H15F3N4O3S2
    Purity:98.28% - 99.51%
    Color and Shape:Solid
    Molecular weight:444.45

    Ref: TM-T17244

  • VU0152100
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    VU0152100

    CAS:
    <p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>
    Formula:C18H19N3O2S
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:341.43

    Ref: TM-T17238

  • Ipratropium Bromide
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    Ipratropium Bromide

    CAS:
    <p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>
    Formula:C20H30BrNO3
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:412.37

    Ref: TM-T6547

  • VU0119498
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    VU0119498

    CAS:
    <p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>
    Formula:C15H10BrNO2
    Purity:97.56%
    Color and Shape:Solid
    Molecular weight:316.15

    Ref: TM-T8224

  • Succinylcholine Chloride Dihydrate
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    Succinylcholine Chloride Dihydrate

    CAS:
    <p>Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.</p>
    Formula:C14H30N2O4·2Cl·2H2O
    Purity:99.87%
    Color and Shape:White Solid
    Molecular weight:397.34

    Ref: TM-T6684

  • VU10010
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    VU10010

    CAS:
    <p>VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.</p>
    Formula:C17H16ClN3OS
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:345.85

    Ref: TM-T23513

  • Procyclidine hydrochloride
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    Procyclidine hydrochloride

    CAS:
    <p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>
    Formula:C19H30ClNO
    Purity:99.24% - 99.88%
    Color and Shape:Crystals From Petroleum Ether White Powder
    Molecular weight:323.9

    Ref: TM-T4979

  • Oxotremorine sesquifumarate
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    Oxotremorine sesquifumarate

    CAS:
    <p>Oxotremorine sesquifumarate is a muscarinic agonist.</p>
    Formula:C12H18N2OC4H4O4
    Purity:97.94%
    Color and Shape:Solid
    Molecular weight:380.39

    Ref: TM-T23116

  • TQS
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    TQS

    CAS:
    <p>TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.</p>
    Formula:C22H20N2O2S
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:376.47

    Ref: TM-T23469