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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 575 products of "AChR"

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  • MC-Val-Cit-PAB
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    MC-Val-Cit-PAB

    CAS:
    <p>MC-Val-Cit-PAB: cathepsin-cleavable ADC linker used in FDA-approved brentuximab vedotin.</p>
    Formula:C28H40N6O7
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:572.65

    Ref: TM-T5149

  • Revefenacin
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    Revefenacin

    CAS:
    <p>Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.</p>
    Formula:C35H43N5O4
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:597.75

    Ref: TM-T7392

  • Nitrocaramiphen hydrochloride
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    Nitrocaramiphen hydrochloride

    CAS:
    <p>Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.</p>
    Formula:C18H27ClN2O4
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:370.87

    Ref: TM-T23071

  • Piperidolate
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    Piperidolate

    CAS:
    <p>Piperidolate inhibits intestinal cramp induced by acetylcholine</p>
    Formula:C21H25NO2
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:323.43

    Ref: TM-T7405

  • PNU-282987 S enantiomer free base
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    PNU-282987 S enantiomer free base

    CAS:
    <p>PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).</p>
    Formula:C14H17ClN2O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:264.75

    Ref: TM-T7695

  • VU 0238429
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    VU 0238429

    CAS:
    <p>VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).</p>
    Formula:C17H12F3NO4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:351.28

    Ref: TM-T8007

  • Glycopyrrolate
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    Glycopyrrolate

    CAS:
    <p>Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.</p>
    Formula:C19H28BrNO3
    Purity:99.41% - 99.64%
    Color and Shape:Solid
    Molecular weight:398.33

    Ref: TM-T2387

  • CCMI
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    CCMI

    CAS:
    <p>CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.</p>
    Formula:C19H15Cl2N3O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:388.25

    Ref: TM-T7422

  • W-84 dibromide
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    W-84 dibromide

    CAS:
    <p>W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.</p>
    Formula:C32H44Br2N4O4
    Purity:95.56%
    Color and Shape:Solid
    Molecular weight:708.52

    Ref: TM-T23524

  • Prifinium bromide
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    Prifinium bromide

    CAS:
    <p>Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.</p>
    Formula:C22H28BrN
    Purity:97.99%
    Color and Shape:Solid
    Molecular weight:386.37

    Ref: TM-T9420

  • Nor-benzetimide
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    Nor-benzetimide

    CAS:
    <p>Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.</p>
    Formula:C16H20N2O2
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:272.34

    Ref: TM-T22380

  • PNU-120596
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    PNU-120596

    CAS:
    <p>PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.</p>
    Formula:C13H14ClN3O4
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:311.72

    Ref: TM-T6950

  • MC-Val-Cit-PABC-PNP
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    MC-Val-Cit-PABC-PNP

    CAS:
    <p>MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.</p>
    Formula:C35H43N7O11
    Purity:97.2% - 98.055%
    Color and Shape:Solid
    Molecular weight:737.76

    Ref: TM-T3503

  • Blarcamesine
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    Blarcamesine

    CAS:
    <p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>
    Formula:C19H23NO
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:281.39

    Ref: TM-T7780

  • (S)-UFR2709
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    (S)-UFR2709

    CAS:
    <p>(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.</p>
    Formula:C13H17NO2
    Color and Shape:Solid
    Molecular weight:219.284

    Ref: TM-T38903

  • Mc-​Val-​Ala-​PAB
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    Mc-​Val-​Ala-​PAB

    CAS:
    <p>Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).</p>
    Formula:C25H34N4O6
    Purity:98.34% - 99.24%
    Color and Shape:Solid
    Molecular weight:486.56

    Ref: TM-T4289

  • PHA 568487
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    PHA 568487

    CAS:
    <p>PHA 568487: α-7 nAChR agonist, rapid brain uptake, lessens oxidative stress &amp; neuroinflammation.</p>
    Formula:C20H24N2O7
    Color and Shape:Solid
    Molecular weight:404.419

    Ref: TM-T61987

  • VU0152099
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    VU0152099

    CAS:
    <p>VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).</p>
    Formula:C18H17N3O3S
    Purity:98.46%
    Color and Shape:Solid
    Molecular weight:355.41

    Ref: TM-T29123

  • Bestim
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    Bestim

    CAS:
    <p>Bestim is an immunomodulatory dipeptide that is synthetic.</p>
    Formula:C16H19N3O5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:333.34

    Ref: TM-T25146

  • Oxyphenonium bromide
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    Oxyphenonium bromide

    CAS:
    <p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>
    Formula:C21H34BrNO3
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:428.404

    Ref: TM-T33846