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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 625 products for "AChR".

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    Rivanicline hydrochloride

    Rivanicline (RJR-2403) hydrochloride is an agonist of neuronal nicotinic receptors. It shows high selectivity for nAChR in the rat cerebral cortex (Ki= 26 nM, EC50= 732 nM) and the α4β2 subtype (Ki= 26 nM, EC50= 16 μM). This compound effectively restores learning and cognitive function impairments and is applicable in research on neurodegenerative diseases such as schizophrenia or Alzheimer's disease.

    Ref: TM-T211611

  • Flupyradifurone
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    Flupyradifurone

    CAS:
    Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.
    Formula:C12H11ClF2N2O2
    Purity:99.83%
    Color and Shape:White Solid
    Molecular weight:288.678

    Ref: TM-T74394

  • CDD0102 HCl
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    CDD0102 HCl

    CAS:
    CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.
    Formula:C8H13ClN4O
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:216.67

    Ref: TM-T80662

  • Migrastatin
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    Migrastatin

    CAS:
    Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic
    Formula:C27H39NO7
    Color and Shape:Solid
    Molecular weight:489.609

    Ref: TM-T35616

  • Navafenterol
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    Navafenterol

    CAS:
    AZD-8871, a potential COPD and asthma treatment, may work well with ICS.
    Formula:C38H42N6O6S2
    Color and Shape:Solid
    Molecular weight:742.91

    Ref: TM-T30264

  • NNC 11-1607
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    NNC 11-1607

    CAS:
    NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.
    Formula:C30H32N6O2S2
    Color and Shape:Solid
    Molecular weight:572.74

    Ref: TM-T28181

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    Bis-Br-ANT-ATP tetrasodium

    Bis-Br-ANT-ATP(tetrasodium) is a fluorescent derivative of adenosine-5'-triphosphate (ATP). It selectively inhibits the adenylyl cyclase toxin CyaA of Bordetella pertussis with a Ki of 12.6 nM. This compound is utilized in research related to whooping cough.
    Color and Shape:Odour Solid

    Ref: TM-T211858

  • VU6028418
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    VU6028418

    CAS:
    VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).
    Formula:C23H27F3N4O
    Color and Shape:Solid
    Molecular weight:432.4819

    Ref: TM-T71675

  • ANQ-9040
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    ANQ-9040

    CAS:
    ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.
    Formula:C36H58N2O5S
    Color and Shape:Solid
    Molecular weight:630.92

    Ref: TM-T30079

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    AC2 selective-IN-1

    AC2 selective-IN-1 is an effective (IC50=4.45 μM), non-toxic, and selective inhibitor of mAC2.
    Formula:C41H47N8O8P
    Color and Shape:Solid
    Molecular weight:810.32545

    Ref: TM-T208788

  • [D-Trp7,9,10]-Substance P
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    [D-Trp7,9,10]-Substance P

    CAS:
    Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
    Formula:C79H105N21O13S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1588.89

    Ref: TM-TP1932

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    α7 nAChR Modulator-3

    α7nAChRModulator-3 (Compound 6p) is a positive allosteric modulator of α7nAChR, with an IC50 value of 1.3 μM. This compound is utilized in studies to inhibit auditory gating deficits in mouse models resembling schizophrenia.
    Formula:C17H13Cl2FN4OS
    Color and Shape:Solid
    Molecular weight:410.01712

    Ref: TM-T209321

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    LtIA-F

    LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.
    Formula:C86H121N25O22S4
    Color and Shape:Solid
    Molecular weight:1985.31

    Ref: TM-T75355

  • Muscarine
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    Muscarine

    CAS:
    Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.
    Formula:C9H20NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:174.26

    Ref: TM-T24507

  • (S)-Dinotefuran
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    (S)-Dinotefuran

    CAS:
    (S)-Dinotefuran, a neonicotinoid, more toxic to bees than its R-isomer, targets α8 nAChR.
    Formula:C7H14N4O3
    Color and Shape:Solid
    Molecular weight:202.21

    Ref: TM-T75302

  • Fentonium bromide
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    Fentonium bromide

    CAS:
    Fentonium bromide is a biochemical.
    Formula:C31H34BrNO4
    Color and Shape:Solid
    Molecular weight:564.51

    Ref: TM-T31781

  • nAChR modulator-2
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    nAChR modulator-2

    CAS:
    nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .
    Formula:C12H8ClN3O2
    Color and Shape:Solid
    Molecular weight:261.66

    Ref: TM-T74397

  • nAChR modulator-1
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    nAChR modulator-1

    CAS:
    nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .
    Formula:C12H8ClN3O2
    Color and Shape:Solid
    Molecular weight:261.66

    Ref: TM-T74396

  • Octamylamine
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    Octamylamine

    CAS:
    Octamylamine is a bioactive chemical.
    Formula:C13H29N
    Color and Shape:Solid
    Molecular weight:199.3761

    Ref: TM-T33778

  • Ebiratide
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    Ebiratide

    CAS:
    Ebiratide is an analog of ACTH 4-9.
    Formula:C48H73N11O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:996.23

    Ref: TM-TP2379