AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
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PNU-282987 S enantiomer free base
CAS:737727-12-7
PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).
Formula:
C14H17ClN2O
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
264.75
Ref: TM-T7695
| 1mg | 157.00 € | ||
| 5mg | 384.00 € | ||
| 10mg | 538.00 € | ||
| 25mg | 827.00 € | ||
| 50mg | 1,132.00 € | ||
| 100mg | 1,531.00 € | ||
| 1mL*10mM (DMSO) | 445.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Darifenacin
CAS:133099-04-4
Darifenacin (UK-88525) is a muscarinic receptor M3 antagonist with anticonvulsant activity and can be used …
Formula:
C28H30N2O2
Color and Shape:
Liquid
Molecular weight:
426.55
Ref: TM-T62320
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 275.00 € | ||
| 100mg | 409.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pozanicline dihydrochloride
CAS:161416-61-1
Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki …
Formula:
C11H18Cl2N2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
265.18
Ref: TM-T12525
| 2mg | 85.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Lupinine
CAS:486-70-4
Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE …
Formula:
C10H19NO
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
169.26
Ref: TM-FR16605
| 1mg | 95.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 271.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 672.00 € | ||
| 100mg | 918.00 € | ||
| 500mg | 1,840.00 € | ||
| 1ml*10 (DMSO) | 151.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Glycopyrrolate
CAS:596-51-0
Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.
Formula:
C19H28BrNO3
Purity:
99.41% - 99.86%
Color and Shape:
Solid
Molecular weight:
398.33
Ref: TM-T2387
| 5mg | 38.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 127.00 € | ||
| 500mg | 299.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Donepezil Hydrochloride
CAS:120011-70-3
Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 …
Formula:
C24H29NO3·HCl
Purity:
99.55% - 99.8%
Color and Shape:
White To Off-White Crystalline Solid
Molecular weight:
415.96
Ref: TM-T6478
| 25mg | 57.00 € | ||
| 50mg | 73.00 € | ||
| 100mg | 96.00 € | ||
| 200mg | 124.00 € | ||
| 500mg | 202.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY2119620
CAS:886047-22-9
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.
Formula:
C19H24ClN5O3S
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
437.94
Ref: TM-T6575
| 1mg | 56.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 442.00 € | ||
| 100mg | 621.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VU0467154
CAS:1451993-15-9
VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.
Formula:
C17H15F3N4O3S2
Purity:
98.05% - 98.28%
Color and Shape:
Solid
Molecular weight:
444.45
Ref: TM-T17244
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 248.00 € | ||
| 100mg | 363.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nitenpyram
CAS:150824-47-8
Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat …
Formula:
C11H15ClN4O2
Purity:
98.42%
Color and Shape:
Light-Yellow Crystal
Molecular weight:
270.72
Ref: TM-T6607
| 100mg | 50.00 € | ||
| 200mg | 74.00 € | ||
| 500mg | 129.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
suvn-911
CAS:2414674-71-6
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = …
Formula:
C11H14Cl2N2O
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
261.15
Ref: TM-T9787
| 1mg | 69.00 € | ||
| 5mg | 136.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | 345.00 € | ||
| 50mg | 491.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 902.00 € | ||
| 1mL*10mM (DMSO) | 175.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(-)-(S)-B-973B
CAS:2244989-34-0
(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
Formula:
C24H26F2N6O
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
452.5
Ref: TM-T17300
| 1mg | 49.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 508.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Succinylcholine Chloride Dihydrate
CAS:6101-15-1
Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a …
Formula:
C14H30N2O4·2Cl·2H2O
Purity:
99.91%
Color and Shape:
White Solid
Molecular weight:
397.34
Ref: TM-T6684
| 1g | 497.00 € | ||
| 10mg | 39.00 € | ||
| 25mg | 55.00 € | ||
| 50mg | 71.00 € | ||
| 100mg | 115.00 € | ||
| 200mg | 203.00 € | ||
| 500mg | 337.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VU0238441
CAS:85511-68-8
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
Formula:
C16H9ClF3NO2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
339.7
Ref: TM-T8219
| 10mg | 41.00 € | ||
| 25mg | 55.00 € | ||
| 50mg | 75.00 € | ||
| 100mg | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Solifenacin
CAS:242478-37-1
Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis …
Formula:
C23H26N2O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
362.46
Ref: TM-T8147
| 25mg | 45.00 € | ||
| 50mg | 62.00 € | ||
| 100mg | 89.00 € | ||
| 500mg | 204.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CCMI
CAS:917837-54-8
CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.
Formula:
C19H15Cl2N3O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
388.25
Ref: TM-T7422
| 2mg | 39.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Trihexyphenidyl hydrochloride
CAS:52-49-3
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
Formula:
C20H32ClNO
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
337.927
Ref: TM-T7002
| 500mg | 59.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NS 1738
CAS:501684-93-1
NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors …
Formula:
C14H9Cl2F3N2O2
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
365.13
Ref: TM-T7884
| 5mg | 51.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Varenicline Tartrate
CAS:375815-87-5
Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR …
Formula:
C13H13N3·C4H6O6
Purity:
99.9% - ≥95%
Color and Shape:
Tan Solid
Molecular weight:
361.35
Ref: TM-T1657
| 5mg | 35.00 € | ||
| 10mg | 47.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 119.00 € | ||
| 100mg | 183.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
W-84 dibromide
CAS:21093-51-6
W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.
Formula:
C32H44Br2N4O4
Purity:
95.56%
Color and Shape:
Solid
Molecular weight:
708.52
Ref: TM-T23524
| 2mg | 34.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 236.00 € | ||
| 100mg | 351.00 € | ||
| 200mg | 499.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
JHU37152
CAS:2369979-67-7
JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: …
Formula:
C19H20ClFN4
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
358.84
Ref: TM-T9019
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 360.00 € | ||
| 200mg | 512.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
