AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
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PNU-282987
CAS:123464-89-1
PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; …
Formula:
C14H18Cl2N2O
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
301.21
Ref: TM-T2422
| 5mg | 48.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 223.00 € | ||
| 100mg | 410.00 € | ||
| 200mg | 544.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Clothianidin
CAS:210880-92-5
Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.
Formula:
C6H8ClN5O2S
Purity:
99.71%
Color and Shape:
Solid Powder
Molecular weight:
249.68
Ref: TM-T21153
| 1g | 128.00 € | ||
| 100mg | 45.00 € | ||
| 200mg | 60.00 € | ||
| 500mg | 88.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nor-benzetimide
CAS:19315-71-0
Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.
Formula:
C16H20N2O2
Purity:
98.63%
Color and Shape:
Solid
Molecular weight:
272.34
Ref: TM-T22380
| 1mg | 89.00 € | ||
| 2mg | 122.00 € | ||
| 5mg | 181.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 446.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 835.00 € | ||
| 200mg | 1,116.00 € | ||
| 1mL*10mM (DMSO) | 180.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VU0357017 hydrochloride
CAS:1135242-13-5
VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to …
Formula:
C18H28ClN3O3
Purity:
99% - 99.97%
Color and Shape:
Solid
Molecular weight:
369.89
Ref: TM-T3619
| 2mg | 41.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 364.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Piperidolate hydrochloride
CAS:129-77-1
Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.
Formula:
C21H26ClNO2
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
359.89
Ref: TM-T7555
| 25mg | 42.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 81.00 € | ||
| 200mg | 123.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VU10010
CAS:633283-39-3
VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.
Formula:
C17H16ClN3OS
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
345.85
Ref: TM-T23513
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 392.00 € | ||
| 100mg | 575.00 € | ||
| 500mg | 1,197.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Coluracetam
CAS:135463-81-9
Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.
Formula:
C19H23N3O3
Purity:
99.96%
Color and Shape:
Solid
Molecular weight:
341.4
Ref: TM-T7591
| 1g | 241.00 € | ||
| 10mg | 37.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 67.00 € | ||
| 100mg | 80.00 € | ||
| 500mg | 167.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cyclodrine hydrochloride
CAS:78853-39-1
Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that …
Formula:
C19H30ClNO3
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
355.9
Ref: TM-T10914
| 1mg | 651.00 € | ||
| 5mg | 1,672.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mAChR-IN-1 hydrochloride
CAS:119391-73-0
mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 …
Formula:
C23H26ClIN2O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
524.82
Ref: TM-T5655
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 312.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 542.00 € | ||
| 200mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Revefenacin
CAS:864750-70-9
Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : …
Formula:
C35H43N5O4
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
597.75
Ref: TM-T7392
| 1mg | 41.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 523.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tacrine hydrochloride (hydrate)
CAS:206658-92-6
Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier.
Formula:
C13H14N2·XHCl·XH2O
Purity:
99.5% - 99.89%
Color and Shape:
Solid
Molecular weight:
234.72
Ref: TM-T2191
| 100mg | 56.00 € | ||
| 200mg | 78.00 € | ||
| 500mg | 106.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PSEM 89S TFA
CAS:1336913-03-1
PSEM 89S TFA is a brain-penetrant and selective ion channels agonist, and is orthogonally selective …
Formula:
C18H23F3N2O5
Purity:
99.90%
Color and Shape:
Solid
Molecular weight:
404.38
Ref: TM-T8552
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 378.00 € | ||
| 200mg | 533.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VU0119498
CAS:79183-37-2
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, …
Formula:
C15H10BrNO2
Purity:
97.56%
Color and Shape:
Solid
Molecular weight:
316.15
Ref: TM-T8224
| 10mg | 35.00 € | ||
| 25mg | 56.00 € | ||
| 50mg | 85.00 € | ||
| 100mg | 113.00 € | ||
| 200mg | 169.00 € | ||
| 1mL*10mM (DMSO) | 38.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VU0152099
CAS:612514-42-8
VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).
Formula:
C18H17N3O3S
Purity:
98.46%
Color and Shape:
Solid
Molecular weight:
355.41
Ref: TM-T29123
| 5mg | 34.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 247.00 € | ||
| 200mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NS3861
CAS:216853-59-7
NS3861 is a selective agonist for α3β4/α4β2 nAChRs, preferring β-subunits, with no effect on α4-based …
Formula:
C12H14BrNS
Purity:
99.40%
Color and Shape:
Solid
Molecular weight:
284.22
Ref: TM-T9542
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 435.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TQS
CAS:353483-92-8
TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.
Formula:
C22H20N2O2S
Purity:
98.56%
Color and Shape:
Solid
Molecular weight:
376.47
Ref: TM-T23469
| 2mg | 33.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 488.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Thiacloprid
CAS:111988-49-9
Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.
Formula:
C10H9ClN4S
Purity:
98.66%
Color and Shape:
Yellowish Crystalline Powder
Molecular weight:
252.72
Ref: TM-T38272
| 100mg | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PHA 568487 free base
CAS:527680-56-4
PHA 568487 free base, an α7 nicotinic receptor agonist, designed to reduce bioactivation and improve …
Formula:
C16H20N2O3
Purity:
99%
Color and Shape:
Solid
Molecular weight:
288.34
Ref: TM-T23146
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 310.00 € | ||
| 200mg | 434.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nanofin
CAS:504-03-0
Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.
Formula:
C7H15N
Purity:
99.818%
Color and Shape:
Clear Colorless To Slightly Yellow Liquid
Molecular weight:
113.2
Ref: TM-T1007
| 1g | 37.00 € | ||
| 5g | 76.00 € | ||
| 10g | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nitrobenzylthioinosine
CAS:38048-32-7
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high …
Formula:
C17H17N5O6S
Purity:
98.83% - 99.69%
Color and Shape:
Off-White Solid
Molecular weight:
419.41
Ref: TM-T8551
| 1g | 1,004.00 € | ||
| 5mg | 47.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 279.00 € | ||
| 500mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
