NMDAR
N-Methyl-D-Aspartate Receptor (NMDAR) inhibitors are compounds that block the activity of NMDARs, a subtype of glutamate receptors that play a critical role in synaptic plasticity, learning, and memory. Overactivation of NMDARs is implicated in excitotoxicity, which can lead to neuronal damage and is associated with conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. NMDAR inhibitors are essential tools for studying excitotoxicity and for developing neuroprotective therapies. At CymitQuimica, we offer a range of NMDAR inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 15 products for "NMDAR".
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SDZ 220-040 ammonium
SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders.Formula:C16H19Cl2N2O6PPurity:99.93%Color and Shape:White SolidMolecular weight:437.21FP802 2HCl
CAS:FP802 2HCl is an orally active TwinF interface inhibitor, neuroprotective, disrupts the toxicity of the NMDAR/TRPM4 death complex.Formula:C11H19Cl3N2Purity:98%Molecular weight:285.64NT 13 acetate
NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.Formula:C20H34N4O9Purity:98%Color and Shape:SolidMolecular weight:474.51S1R agonist 2
CAS:S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.Formula:C21H27NOPurity:99.66%Color and Shape:SolidMolecular weight:309.45EVT-101 free base
CAS:EVT-101 free base (ENS-101) NR2B NMDA receptor antagonist for neuropharmacology, depression research, glutamatergic signaling and CNS pathway studies.Formula:C16H13F3N4Color and Shape:SolidMolecular weight:318.30SDZ 220-581 hydrochloride
CAS:SDZ 220-581 hydrochloride is a potent competitive NMDA receptor antagonist (pKᵢ = 7.7) with good oral bioavailability.Formula:C16H18Cl2NO5PPurity:98%Color and Shape:White SolidMolecular weight:406.20Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.5% - 99.9%Color and Shape:Yellow SolidMolecular weight:420.39CNS-5161
CAS:CNS-5161 is a selective, non-competitive NMDA receptor antagonist that primarily targets the GluN2B subunit.Formula:C16H18ClN3S2Purity:99.61%Color and Shape:SolidMolecular weight:351.92TCN 201
CAS:TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.Formula:C21H17ClFN3O4SPurity:98.5%Color and Shape:SolidMolecular weight:461.894Glypromate acetate
Glypromate acetate is a neuroprotective agent, is a weak NMDA receptor agonist.Formula:C14H23N3O8Purity:99.94%Color and Shape:SolidMolecular weight:361.35Ref: TM-T7778L
2mg37.00€5mg52.00€1mL*10mM (DMSO)57.00€10mg74.00€25mg119.00€50mg160.00€100mg225.00€200mg314.00€Perzinfotel
CAS:Perzinfotel is a selective NMDA antagonist; IC50=34 nM; neuroprotective agent; used for stroke and pain research.Formula:C9H13N2O5PPurity:98.35%Color and Shape:Yellow SolidMolecular weight:260.18Pregnanolone sulfate (pyridinium)
CAS:Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].Formula:C26H39NO5SPurity:98%Color and Shape:White SolidMolecular weight:477.66R-(+)-EU-1180-453
CAS:R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Formula:C22H21FN2O3Purity:99.88%Color and Shape:SolidMolecular weight:380.41BMS-986163
CAS:BMS-986163, GluN2B negative allosteric modulator prodrug, converts to BMS-986169 (Ki=4 nM), antidepressant-like activity.Formula:C23H28FN2O5PPurity:98%Color and Shape:SolidMolecular weight:462.45Blixeprodil
CAS:Blixeprodil (GM-1020) is an oral NMDA antagonist (Ki=3.25 µM, IC₅₀=1.192 µM) that crosses the BBB and shows antidepressant effects.Formula:C13H16FNOPurity:>99.99%Color and Shape:SolidMolecular weight:221.27
