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NMDAR

NMDAR

N-Methyl-D-Aspartate Receptor (NMDAR) inhibitors are compounds that block the activity of NMDARs, a subtype of glutamate receptors that play a critical role in synaptic plasticity, learning, and memory. Overactivation of NMDARs is implicated in excitotoxicity, which can lead to neuronal damage and is associated with conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. NMDAR inhibitors are essential tools for studying excitotoxicity and for developing neuroprotective therapies. At CymitQuimica, we offer a range of NMDAR inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.

Found 15 products for "NMDAR".

  • SDZ 220-040 ammonium
    Targetmol
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    SDZ 220-040 ammonium

    SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders.
    Formula:C16H19Cl2N2O6P
    Purity:99.93%
    Color and Shape:White Solid
    Molecular weight:437.21

    Ref: TM-T23344L

  • FP802 2HCl
    Targetmol
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    FP802 2HCl

    CAS:
    FP802 2HCl is an orally active TwinF interface inhibitor, neuroprotective, disrupts the toxicity of the NMDAR/TRPM4 death complex.
    Formula:C11H19Cl3N2
    Purity:98%
    Molecular weight:285.64

    Ref: TM-TYD-02816

  • NT 13 acetate
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    NT 13 acetate

    NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.
    Formula:C20H34N4O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:474.51

    Ref: TM-TP1023L

  • S1R agonist 2
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    S1R agonist 2

    CAS:
    S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
    Formula:C21H27NO
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:309.4452

    Ref: TM-T72059

  • EVT-101 free base
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    EVT-101 free base

    CAS:
    EVT-101 free base (ENS-101) NR2B NMDA receptor antagonist for neuropharmacology, depression research, glutamatergic signaling and CNS pathway studies.
    Formula:C16H13F3N4
    Color and Shape:Solid
    Molecular weight:318.30

    Ref: TM-T68973

  • SDZ 220-581 hydrochloride
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    SDZ 220-581 hydrochloride

    CAS:
    SDZ 220-581 hydrochloride is a potent competitive NMDA receptor antagonist (pKᵢ = 7.7) with good oral bioavailability.
    Formula:C16H18Cl2NO5P
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:406.20

    Ref: TM-T12889L

  • Flupirtine maleate
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    Flupirtine maleate

    CAS:
    Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.
    Formula:C15H17FN4O2·C4H4O4
    Purity:99.5% - 99.9%
    Color and Shape:Yellow Solid
    Molecular weight:420.39

    Ref: TM-T6504

  • CNS-5161
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    CNS-5161

    CAS:
    CNS-5161 is a selective, non-competitive NMDA receptor antagonist that primarily targets the GluN2B subunit.
    Formula:C16H18ClN3S2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:351.92

    Ref: TM-T27055

  • TCN 201
    Targetmol
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    TCN 201

    CAS:
    TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.
    Formula:C21H17ClFN3O4S
    Purity:98.5%
    Color and Shape:Solid
    Molecular weight:461.894

    Ref: TM-T7870

  • Glypromate acetate
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    Glypromate acetate

    Glypromate acetate is a neuroprotective agent, is a weak NMDA receptor agonist.
    Formula:C14H23N3O8
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:361.35

    Ref: TM-T7778L

  • Perzinfotel
    Targetmol
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    Perzinfotel

    CAS:
    Perzinfotel is a selective NMDA antagonist; IC50=34 nM; neuroprotective agent; used for stroke and pain research.
    Formula:C9H13N2O5P
    Purity:98.35%
    Color and Shape:Yellow Solid
    Molecular weight:260.18

    Ref: TM-T16473

  • Pregnanolone sulfate (pyridinium)
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    Pregnanolone sulfate (pyridinium)

    CAS:
    Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].
    Formula:C26H39NO5S
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:477.657

    Ref: TM-T81409

  • R-(+)-EU-1180-453
    Targetmol
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    R-(+)-EU-1180-453

    CAS:
    R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.
    Formula:C22H21FN2O3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:380.41

    Ref: TM-T69611

  • BMS-986163
    Targetmol
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    BMS-986163

    CAS:
    BMS-986163, GluN2B negative allosteric modulator prodrug, converts to BMS-986169 (Ki=4 nM), antidepressant-like activity.
    Formula:C23H28FN2O5P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.45

    Ref: TM-T14686

  • Blixeprodil
    Targetmol
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    Blixeprodil

    CAS:
    Blixeprodil (GM-1020) is an oral NMDA antagonist (Ki=3.25 µM, IC₅₀=1.192 µM) that crosses the BBB and shows antidepressant effects.
    Formula:C13H16FNO
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:221.27

    Ref: TM-T206599