p97
p97 inhibitors are compounds that inhibit p97, also known as Valosin-Containing Protein (VCP), an ATPase involved in various cellular processes, including protein degradation, cell cycle regulation, and DNA repair. p97 is a key player in the ubiquitin-proteasome system and its inhibition is of interest in cancer research, neurodegenerative diseases, and other disorders where protein homeostasis is disrupted. At CymitQuimica, we offer p97 inhibitors to support your research in proteostasis, neurobiology, and cancer therapy.
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NSC819701
NSC819701 is a triazole-based inhibitor of p97ATPase. It inhibits the activity of p97ATPase by binding …
Formula:
C30H32F2N8O3S
Color and Shape:
Solid
Molecular weight:
622.69
Ref: TM-T89915
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
NSC799462
NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a …
Formula:
C30H32F2N6O3S
Color and Shape:
Solid
Molecular weight:
594.68
Ref: TM-T200146
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
UP12
CAS:443353-87-5
UP12 enhances ATPase activity by activating valosin-containing protein (VCP), with an EC50 of 2.57 μM.
Formula:
C23H16ClN3O3S
Color and Shape:
Solid
Molecular weight:
449.91
Ref: TM-T203349
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
UP158
CAS:489402-33-7
UP158 enhances ATPase activity and stimulates valosin-containing protein (VCP), with an EC50 of 2.57 μM.
Formula:
C17H17ClN4O2
Color and Shape:
Solid
Molecular weight:
344.8
Ref: TM-T203467
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
UP163
CAS:591242-60-3
UP163 enhances ATPase activity and activates valosin-containing protein (VCP), with an EC50 of 9.0 μM. …
Formula:
C20H15ClN2O5S
Color and Shape:
Solid
Molecular weight:
430.86
Ref: TM-T203431
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
MSC1094308
CAS:2219320-08-6
MSC1094308 is a reversible, non-ATP-competitive inhibitor targeting type II AAA ATPase (VCP/p97) and type I …
Formula:
C29H29F3N2
Color and Shape:
Solid
Molecular weight:
462.55
Ref: TM-T12114
| 2mg | 293.00 € |
Estimated delivery in United States, on Monday 2 Jun 2025
CB-5083
CAS:1542705-92-9
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
Formula:
C24H23N5O2
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
413.47
Ref: TM-T6796
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 469.00 € | ||
| 100mg | 687.00 € | ||
| 500mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
ML240
CAS:1346527-98-7
ML240 is a selective, ATP-competitive p97 inhibitor.
Formula:
C23H20N6O
Purity:
100% - 99.66%
Color and Shape:
Solid
Molecular weight:
396.44
Ref: TM-T3535
| 1mg | 38.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 528.00 € | ||
| 200mg | 752.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
ML241 hydrochloride
CAS:2070015-13-1
ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent …
Formula:
C23H25ClN4O
Purity:
99.91% - 99.96%
Color and Shape:
Solid
Molecular weight:
408.92
Ref: TM-T4684
| 5mg | 51.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
ML241
CAS:1346528-06-0
ML241 is a potent and selective inhibitors of p97 ATPase.
Formula:
C23H24N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.46
Ref: TM-T3164
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 444.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
DBEQ
CAS:177355-84-9
DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.
Formula:
C22H20N4
Purity:
98.89% - ≥95%
Color and Shape:
Solid
Molecular weight:
340.42
Ref: TM-T1969
| 5mg | 58.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 410.00 € | ||
| 200mg | 607.00 € | ||
| 500mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
NMS-873
CAS:1418013-75-8
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
Formula:
C27H28N4O3S2
Purity:
99.05% - 99.5%
Color and Shape:
Solid
Molecular weight:
520.67
Ref: TM-T1853
| 2mg | 47.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
NPD8733
CAS:696655-62-6
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein …
Formula:
C18H15NO4
Purity:
98.48%
Color and Shape:
Solid
Molecular weight:
309.32
Ref: TM-T9008
| 1mg | 42.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 399.00 € | ||
| 100mg | 645.00 € | ||
| 500mg | 1,311.00 € | ||
| 1mL*10mM (DMSO) | 183.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
CB-5339
CAS:1863952-15-1
p97-IN-1 is a potent inhibitor of p97 with an IC 50 <30 nM [1].
Formula:
C24H24N6O
Purity:
98.5%
Color and Shape:
Soild
Molecular weight:
412.49
Ref: TM-T60193
| 5mg | 55.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 273.00 € |
Estimated delivery in United States, on Friday 18 Jul 2025
UPCDC30766
CAS:2152623-68-0
UPCDC30766, a potent allosteric inhibitor of p97, exhibits an IC50 of 12 nM and is …
Formula:
C30H32F2N6O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
594.68
Ref: TM-T79255
| 25mg | 3,200.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Friday 1 Aug 2025
