Serine Protease
Serine protease inhibitors are compounds that target and inhibit serine proteases, a group of enzymes characterized by a serine residue at their active site. These proteases are involved in numerous physiological processes, including digestion, immune response, blood coagulation, and inflammation. Serine protease inhibitors are important for studying diseases where these enzymes are dysregulated, such as cardiovascular diseases, cancer, and inflammatory conditions. At CymitQuimica, we provide serine protease inhibitors to support your research in enzymology, disease mechanisms, and therapeutic interventions.
Found 56 products of "Serine Protease"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
TAO Kinase inhibitor 2
CAS:<p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>Formula:C25H24N2O3Purity:98.58%Color and Shape:SoildMolecular weight:400.47BAY-85-8501
CAS:BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)Formula:C22H17F3N4O3SPurity:99.16%Color and Shape:SolidMolecular weight:474.46AE-3763
CAS:AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).Formula:C23H34F3N5O7Purity:98%Color and Shape:SolidMolecular weight:549.54Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidNonacog alfa
CAS:Nonacog alfa (BAX326), a recombinant human factor IX, is utilized in the study of hemophilia B [1].Color and Shape:LiquidElastase (high purity)
Elastase (high purity) is a serine protease that hydrolyzes proteins and peptides.Color and Shape:Odour SolidKKI-5
CAS:<p>KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.</p>Formula:C35H55N11O9Purity:98%Color and Shape:SolidMolecular weight:773.88C1 Esterase Inhibitor (Human)
C1 Esterase Inhibitor (Human) is a glycoprotein derived from human plasma and acts as a serine protease inhibitor. It inactivates enzymes like C1r, C1s, and mannose-binding lectin-associated serine proteases (MASP) through covalent binding. This compound possesses anti-inflammatory properties and is utilized to prevent angioedema attacks associated with hereditary angioedema.Color and Shape:Odour LiquidPhosphorylase Kinase β-Subunit Fragment (420-436)
CAS:Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase.Formula:C79H131N31O25SPurity:98%Color and Shape:SolidMolecular weight:1947.14Patamostat HCl
CAS:<p>Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50</p>Formula:C20H21ClN4O4SPurity:99.15% - 99.76%Color and Shape:SoildMolecular weight:448.92Activated Protein C (390-404), human
CAS:Human Activated Protein C (390-404) peptide derived from serine protease, suppresses APC anticoagulation.Formula:C91H130N22O23Purity:98%Color and Shape:SolidMolecular weight:1900.14α-Methyl-DL-aspartic acid
CAS:α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.Formula:C5H9NO4Purity:99.91%Color and Shape:SolidMolecular weight:147.13Recombinant Trypsin
Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS:Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFormula:C26H36ClN7O7SColor and Shape:SolidMolecular weight:626.12SFTI-1
CAS:SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.Formula:C67H104N18O18S2Color and Shape:SolidMolecular weight:1513.78Ala-Phe-Pro-pNA TFA
Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.Color and Shape:Odour SolidSuc-AAP-Abu-pNA
CAS:Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,Formula:C25H34N6O9Color and Shape:SolidMolecular weight:562.57Tilpisertib fosmecarbil TFA
CAS:Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.Formula:C37H37ClF3N8O9PColor and Shape:SolidMolecular weight:861.16Chymotrypsinogen
CAS:Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .Color and Shape:SolidLonodelestat TFA
<p>Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.</p>Formula:C73H112F3N15O21Color and Shape:SolidMolecular weight:1592.75Tiprelestat
CAS:<p>Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.</p>Formula:C254H416N72O75S10Color and Shape:SolidMolecular weight:5999.09α 1 Antichymotrypsin, Human Plasma
CAS:Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.Color and Shape:SolidMeOSuc-AAPA-CMK
MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].Formula:C20H31ClN4O8Color and Shape:SolidMolecular weight:490.94Roseltide rT1
CAS:Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.Formula:C110H177N31O31S6Color and Shape:SolidMolecular weight:2622.16Urokinase
CAS:<p>Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.</p>Color and Shape:SolidPKR-IN-C51
CAS:PKR-IN-C51 is ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation. Ser/Thr kinase.Formula:C23H21N5Purity:98.94%Color and Shape:SolidMolecular weight:367.45Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Formula:C17H24ClNO4Purity:99.75%Color and Shape:SolidMolecular weight:341.832,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS:2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urineFormula:C13H16O3Purity:99.53% - 99.81%Color and Shape:SolidMolecular weight:220.26ML281
CAS:ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.Formula:C22H19N3O2SPurity:99.12% - 99.87%Color and Shape:SolidMolecular weight:389.47Alvelestat
CAS:Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.Formula:C25H22F3N5O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:545.53KKI-5 acetate(97145-43-2 free base)
KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.Formula:C37H59N11O11Purity:99.44%Color and Shape:SolidMolecular weight:833.95Ceritinib
CAS:<p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C28H36ClN5O3SPurity:98.52% - 99.77%Color and Shape:SolidMolecular weight:558.14WNK-IN-11
CAS:WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Formula:C21H21Cl2N5OSPurity:98.32%Color and Shape:SolidMolecular weight:462.42-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.Formula:C14H7BrClNO2Purity:97.36%Color and Shape:SolidMolecular weight:336.57WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Formula:C21H24F3N7O2Purity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:463.46Lanadelumab
CAS:Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.Purity:95% - 97.4% (SDS-PAGE); 99.2% (SEC-HPLC)Color and Shape:LiquidAnti-Matriptase Antibody
Anti-Matriptase Antibody is a human-derived antibody expressed in CHO cells, targeting Matriptase. It features a huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Matriptase Antibody can be found in HumanIgG1kappa, Isotype Control.Galegenimab
CAS:<p>Galegenimab (FHTR 2163; RG 6147; RO 7171009) is an HTRA1 antibody fragment for AMD research.</p>Purity:95% - 95%Color and Shape:LiquidMEGA-9
CAS:MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.Formula:C16H33NO6Purity:99.9%Color and Shape:SolidMolecular weight:335.44ZD-0892
CAS:<p>ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).</p>Formula:C24H32F3N3O5Purity:95% - 99.53%Color and Shape:SolidMolecular weight:499.52BMS-363131
CAS:BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.Formula:C28H40N6O5Purity:97.99%Color and Shape:SolidMolecular weight:540.65AGLME
CAS:AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.Formula:C11H21N3O4Color and Shape:SolidMolecular weight:259.3WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Formula:C13H15BrCl2N2O4SPurity:98.09%Color and Shape:SolidMolecular weight:446.14Lodelaben
CAS:Lodelaben (Declaben, SC-39026) is a reversible, non-competitive,specific inhibitor of human neutrophil elastase (HNE) with high potency (IC50=0.5 μM).Formula:C25H41ClO3Purity:99.62% - >99.99%Color and Shape:SolidMolecular weight:425.04APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formula:C22H28N6O4Purity:99.8%Color and Shape:SolidMolecular weight:440.5IPR-803
CAS:IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.Formula:C27H23N3O4Purity:95%Color and Shape:SolidMolecular weight:453.49p-Aminobenzamidine dihydrochloride
CAS:<p>4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type</p>Formula:C7H11Cl2N3Purity:99.00% - 99.56%Color and Shape:SolidMolecular weight:208.088ZD8321
CAS:<p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>Formula:C18H28F3N3O5Purity:98%Color and Shape:SolidMolecular weight:423.43ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99LM-030
CAS:LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).Formula:C46H72N8O12Color and Shape:SolidMolecular weight:929.11AZD-9819
CAS:AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).Formula:C25H19F3N6O2Purity:100% - 99.18%Color and Shape:SolidMolecular weight:492.45FK706
CAS:FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.Formula:C26H33F3N4NaO7Color and Shape:SolidMolecular weight:593.556TMPRSS6-IN-1 TFA
<p>TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.</p>Formula:C35H41F3N8O6S2Color and Shape:SolidMolecular weight:790.875Feniralstat
CAS:Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.Formula:C26H25F2N5O4Purity:99.52%Color and Shape:SolidMolecular weight:509.51MeO-Suc-Ala-Ala-Pro-Ala-CMK
CAS:MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).Formula:C20H31ClN4O7Color and Shape:SolidMolecular weight:474.936Matriptase-IN-2 free base
CAS:Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].Formula:C29H33Cl2N5O3SColor and Shape:SolidMolecular weight:602.58
