Acetyl-CoA Carboxylase

CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor.

(Rac)-Spirotetramat-enol (Compound 8) serves as a ligand for target proteins, utilized in the synthesis of PROTAC ACC degrader.

MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).

Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].

Sethoxydim is an effective herbicide.

Tepraloxydim is an inhibitor of Acetyl-CoA Carboxylase and is effective in controlling weeds.

PROTAC ACC degrader-1 (Compound 9b), an Acetyl-CoA Carboxylase degrader, demonstrates remarkable effectiveness, with a potent activity characterized by an IC 50 of 107.8 μg/mL against Aphis craccivora.

Cycloxydim is a cyclohexene oxime herbicide that is used for the control of grass weeds of many agricultural and horticultural broad-leaved crops.

IRW is an orally active tripeptide extracted from egg whites with angiotensin-converting enzyme (ACE) inhibitory properties. It helps prevent non-alcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD) through the regulation of hepatic lipid metabolism and increased mitochondrial content. IRW reduces hepatic triglyceride levels and lipid droplet size, and enhances liver mitochondrial complexes, citrate synthase activity, and 5'-AMP-activated protein kinase phosphorylation, along with the abundance of microsomal triglyceride transfer protein. It also increases phosphorylated acetyl CoA carboxylase and mitochondrial complexes, making it useful for inflammation-related research.

Spiromesifen is a useful miticide and insecticide in plant breeding. It is particuarly useful against spider mites and whiteflies in vitro.

CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.

Insecticidal agent 26 (Compound A11) is a spirocyclic insecticide that serves as a dual inhibitor of acetyl-coenzyme A carboxylase (ACC) and pyruvate carboxylase (PC) in pests. It exhibits potent insecticidal activity against Sogatella furcifera with an LC50 of 11.0 μg/mL while maintaining good environmental safety for bees. Insecticidal agent 26 is effective for the control of white-backed planthoppers (WBPs).

Cyhalofop-butyl is an ACCase (acetyl-coenzyme A carboxylase) inhibitor and herbicide that suppresses plant lipid synthesis at the meristematic level.

Quizalofop-p-ethyl ((R)-Quizalofop ethyl) is a selective post-emergent herbicide for annual and perennial weeds, acetyl-CoA carboxylase (ACCase) inhibitor.

Clodinafop-propargyl is used to control grass weeds in cereals postemergence, targeting species like Avena and Lolium.

Spiromesifen (Standard) is the standard substance of Spiromesifen, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Spiromesifen is a useful miticide and insecticide in plant breeding. It is particuarly useful against spider mites and whiteflies in vitro.

Fluazifop-P-butyl (Standard) is the standard substance of Fluazifop-P-butyl, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase).

Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.

(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.