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Protease-activated Receptor

Protease-activated Receptor

Protease-activated Receptor (PAR) inhibitors are compounds that target and inhibit the activity of PARs, a family of G-protein-coupled receptors that are activated by proteolytic cleavage. These receptors play a role in various physiological processes, including coagulation, inflammation, and tissue repair. PAR inhibitors are valuable tools for studying the mechanisms of these processes and their involvement in diseases such as cancer, cardiovascular disorders, and chronic inflammation. At CymitQuimica, we provide PAR inhibitors to aid your research in signal transduction, immune response, and therapeutic discovery.

Found 54 products of "Protease-activated Receptor"

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  • FLLRN
    Targetmol
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    FLLRN

    CAS:
    <p>FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.</p>
    Formula:C31H51N9O7
    Color and Shape:Solid
    Molecular weight:661.79

    Ref: TM-T78545

  • YFLLRNP
    Targetmol
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    YFLLRNP

    CAS:
    <p>YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.</p>
    Formula:C45H67N11O10
    Color and Shape:Solid
    Molecular weight:922.08

    Ref: TM-T80235

  • TRAP-5 amide
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    TRAP-5 amide

    CAS:
    <p>TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].</p>
    Formula:C30H51N9O6
    Color and Shape:Solid
    Molecular weight:633.78

    Ref: TM-T80111

  • CymitQuimica logo
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    PAR 4 (1-6) (TFA)

    <p>PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.</p>
    Formula:C28H41N7O9·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T75904

  • CymitQuimica logo
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    P4pal10 TFA

    <p>P4pal10 TFA, the TFA salt form of P4pal10, serves as an antagonist of the protease-activated receptor 4 (PAR4). This compound inhibits platelet aggregation and thrombin generation induced by tissue factor (TF), exhibiting anticoagulant and antithrombotic activities. Additionally, P4pal10 TFA alleviates carrageenan-induced edema and neutrophil infiltration, and ameliorates damage in rat myocardial ischemia/reperfusion (I/R) models.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP2784

  • TRAP-6 amide TFA
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    TRAP-6 amide TFA

    CAS:
    <p>TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.</p>
    Formula:C36H58F3N11O10
    Color and Shape:Solid
    Molecular weight:861.922

    Ref: TM-T38887

  • TFLLR-NH2(TFA)
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    TFLLR-NH2(TFA)

    CAS:
    <p>TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. EC50: 1.9 μM (PAR1)</p>
    Formula:C33H54F3N9O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:761.83

    Ref: TM-TP1334

  • SLIGRL-NH2
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    SLIGRL-NH2

    CAS:
    <p>SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.</p>
    Formula:C29H56N10O7
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:656.82

    Ref: TM-TP1046

  • Protease-Activated Receptor-2, amide
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    Protease-Activated Receptor-2, amide

    CAS:
    <p>Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M)</p>
    Formula:C28H54N8O7
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:614.78

    Ref: TM-T7513

  • PAR-2-IN-1
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    PAR-2-IN-1

    CAS:
    <p>PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.</p>
    Formula:C12H14ClN3O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:267.71

    Ref: TM-T8917

  • Vorapaxar
    Targetmol
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    Vorapaxar

    CAS:
    <p>Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).</p>
    Formula:C29H33FN2O4
    Purity:98.77% - 99.93%
    Color and Shape:Solid
    Molecular weight:492.58

    Ref: TM-T7013

  • Vorapaxar sulfate
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    Vorapaxar sulfate

    CAS:
    <p>Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.</p>
    Formula:C29H35FN2O8S
    Purity:99.9% - >99.99%
    Color and Shape:Solid
    Molecular weight:590.66

    Ref: TM-T3098

  • I-191
    Targetmol
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    I-191

    CAS:
    <p>I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.</p>
    Formula:C23H26FN5O2
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:423.48

    Ref: TM-T7137

  • TRAP-6
    Targetmol
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    TRAP-6

    CAS:
    <p>TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).</p>
    Formula:C34H56N10O9
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:748.87

    Ref: TM-T7625

  • PAR-4 Agonist Peptide, amide TFA
    Targetmol
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    PAR-4 Agonist Peptide, amide TFA

    CAS:
    <p>PAR-4 agonist peptide doesn't affect PAR-1/PAR-2; blocked by PAR-4 antagonist.</p>
    Formula:C36H49F3N8O9
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:794.82

    Ref: TM-TP1065

  • Protease-Activated Receptor-1, PAR-1 Agonist acetate
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    Protease-Activated Receptor-1, PAR-1 Agonist acetate

    <p>PAR-1 Agonist acetate is a selective PAR-1 agonist that mimics thrombin action.</p>
    Formula:C37H62N10O11
    Purity:98.1800%
    Color and Shape:Solid
    Molecular weight:822.95

    Ref: TM-T38836L

  • PAR-2 Activating Peptide acetate
    Targetmol
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    PAR-2 Activating Peptide acetate

    <p>PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).</p>
    Formula:C31H60N10O9
    Purity:98.5% - 99.92%
    Color and Shape:Solid
    Molecular weight:716.88

    Ref: TM-TP1046L

  • AC-55541
    Targetmol
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    AC-55541

    CAS:
    <p>AC-55541 (AOB2796), a PAR2 agonist, activates PAR2 in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays.</p>
    Formula:C25H20BrN5O3
    Purity:98% - 99.33%
    Color and Shape:Solid
    Molecular weight:518.36

    Ref: TM-T2370

  • VKGILS-NH2 Acetate
    Targetmol
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    VKGILS-NH2 Acetate

    <p>VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.</p>
    Formula:C30H58N8O9
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:674.83

    Ref: TM-T21699L

  • LRGILS-NH2 acetate
    Targetmol
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    LRGILS-NH2 acetate

    <p>LRGILS-NH2 acetate is a PAR-2-inactive reversed peptide.</p>
    Formula:C29H56N10O7
    Purity:96.65%
    Color and Shape:Solid
    Molecular weight:656.82

    Ref: TM-T22933L