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Wnt/beta-catenin

Wnt/beta-catenin

Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.

Found 66 products of "Wnt/beta-catenin"

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  • MSAB
    Targetmol
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    MSAB

    CAS:
    <p>MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.</p>
    Formula:C15H15NO4S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:305.35

    Ref: TM-T8710

  • IWP-4
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    IWP-4

    CAS:
    <p>IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.</p>
    Formula:C23H20N4O3S3
    Purity:98% - 99.59%
    Color and Shape:Solid
    Molecular weight:496.62

    Ref: TM-T4245

  • PRI-724
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    PRI-724

    CAS:
    <p>PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.</p>
    Formula:C33H35N6O7P
    Purity:98.25% - 99.11%
    Color and Shape:Soild
    Molecular weight:658.64

    Ref: TM-T64414

  • Wnt pathway activator 2
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    Wnt pathway activator 2

    CAS:
    <p>Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.</p>
    Formula:C17H15NO4
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:297.31

    Ref: TM-T13345

  • ZW4864 free base
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    ZW4864 free base

    CAS:
    <p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>
    Formula:C33H42N6O3
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:570.72

    Ref: TM-T9642

  • β-catenin/CBP-IN-1
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    β-catenin/CBP-IN-1

    CAS:
    <p>β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin</p>
    Formula:C33H35N6O7P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:658.64

    Ref: TM-T12537

  • GB1874
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    GB1874

    CAS:
    <p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>
    Formula:C24H27N3O2S
    Color and Shape:Solid
    Molecular weight:421.56

    Ref: TM-T71624

  • Wnt/β-catenin agonist 4
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    Wnt/β-catenin agonist 4

    CAS:
    <p>Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.</p>
    Formula:C16H15FN4O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:314.31

    Ref: TM-T60803

  • FzM1
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    FzM1

    CAS:
    <p>FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)</p>
    Formula:C21H16N2O2S
    Purity:99.37% - 99.89%
    Color and Shape:Solid
    Molecular weight:360.43

    Ref: TM-T24076

  • FzM1.8
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    FzM1.8

    CAS:
    <p>FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.</p>
    Formula:C18H14N2O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:322.31

    Ref: TM-T15363

  • Miclxin
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    Miclxin

    CAS:
    <p>Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potent</p>
    Formula:C26H27N5O2
    Purity:99.17% - 99.99%
    Color and Shape:Solid
    Molecular weight:441.52

    Ref: TM-T73415

  • JW 67
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    JW 67

    CAS:
    <p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>
    Formula:C21H18N2O6
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:394.38

    Ref: TM-T22884

  • CDK8-IN-11
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    CDK8-IN-11

    CAS:
    <p>CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.</p>
    Formula:C19H15F3N4O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:388.34

    Ref: TM-T61742

  • Carboxylesterase-IN-3
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    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Formula:C11H6Cl2N4OS
    Purity:97.49% - 98.47%
    Color and Shape:Solid
    Molecular weight:313.16

    Ref: TM-T60788

  • β-Catenin modulator-8
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    β-Catenin modulator-8

    CAS:
    <p>β-Catenin modulator-8 (Compound Ⅸa) is a specific β-catenin modulator for use in cancer research.</p>
    Formula:C17H20N2O2S
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:316.42

    Ref: TM-T205083

  • NRX-103095
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    NRX-103095

    CAS:
    <p>NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.</p>
    Formula:C22H16Cl2F3N3O3S
    Purity:99.58% - 99.95%
    Color and Shape:Solid
    Molecular weight:530.35

    Ref: TM-T63730