Fibroblast Growth Factor Receptor (FGFR)
FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.
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FGFR1 inhibitor 7
FGFR1 Inhibitor 7 (compound 5), a potent FGFR1 tyrosine kinase inhibitor, exhibits an IC50 of …
Formula:
C25H16ClNO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
429.85
Ref: TM-T78830
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
S6K2-IN-1
S6K2-IN-1 (Compound 2) is an inhibitor of S6K2 with an IC50 of 22 nM and …
Formula:
C24H23ClF3N9O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
561.95
Ref: TM-T79871
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Aprutumab
CAS:1634620-63-5
Aprutumab, a human FGFR2 monoclonal antibody, targets FGFR2-IIIB/C and is used in antibody-drug conjugates.
Purity:
98.69% (SEC-HPLC) - 98.69% (SEC-HPLC)
Color and Shape:
Liquid
Molecular weight:
150 kDa
Ref: TM-T76672
| 1mg | 531.00 € | ||
| 5mg | 1,505.00 € | ||
| 10mg | 2,025.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
FGFR1 inhibitor-9
FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor with potent binding affinity, exhibiting an IC50 …
Formula:
C27H20ClNO5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
473.9
Ref: TM-T78832
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
SM27
CAS:6266-54-2
SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be …
Formula:
C21H16N2O9S2
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
504.49
Ref: TM-T24804
| 1mg | 183.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD 173074
CAS:219580-11-7
Formula:
C28H41N7O3
Purity:
>95.0%(HPLC)
Color and Shape:
White to Yellow to Orange powder to crystal
Molecular weight:
523.68
Ref: 3B-P2474
| 10mg | 68.00 € | ||
| 50mg | 191.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Surfen dihydrochloride
CAS:5424-37-3
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade …
Formula:
C21H22Cl2N6O
Purity:
97.08%
Color and Shape:
Solid
Molecular weight:
445.35
Ref: TM-T26240
| 2mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 589.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FGFR2-IN-3
CAS:2549174-42-5
FGFR2-IN-3 is an orally active selective FGFR2 inhibitor[1].
Formula:
C28H24FN7O2
Purity:
99.24%
Color and Shape:
Soild
Molecular weight:
509.53
Ref: TM-T60185
| 1mg | 94.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 616.00 € | ||
| 50mg | 922.00 € | ||
| 100mg | 1,234.00 € | ||
| 1mL*10mM (DMSO) | 222.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD-161570
CAS:192705-80-9
Formula:
C26H35Cl2N7O
Purity:
>98.0%(HPLC)
Color and Shape:
White to Light yellow powder to crystal
Molecular weight:
532.51
Ref: 3B-P2531
| 5mg | 105.00 € | ||
| 25mg | 352.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ON123300
CAS:1357470-29-1
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
Formula:
C24H27N7O
Purity:
99.22% - 99.53%
Color and Shape:
Solid
Molecular weight:
429.52
Ref: TM-T6920
| 1mg | 46.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 146.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 635.00 € | ||
| 500mg | 1,291.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
R1530
CAS:882531-87-5
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
Formula:
C18H14ClFN4O
Purity:
97.96%
Color and Shape:
Solid
Molecular weight:
356.78
Ref: TM-TQ0317
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 552.00 € | ||
| 100mg | 796.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Alofanib
CAS:1612888-66-0
Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect …
Formula:
C19H15N3O6S
Purity:
98.82% - 99.06%
Color and Shape:
Solid
Molecular weight:
413.4
Ref: TM-T5122
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 299.00 € | ||
| 100mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Danusertib
CAS:827318-97-8
Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.
Formula:
C26H30N6O3
Purity:
98% - 98.44%
Color and Shape:
White Powder
Molecular weight:
474.55
Ref: TM-T2094
| 1mg | 59.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 779.00 € | ||
| 500mg | 1,574.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KW-2449
CAS:1000669-72-6
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora …
Formula:
C20H20N4O
Purity:
98.43% - 99.89%
Color and Shape:
Solid
Molecular weight:
332.4
Ref: TM-T2341
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 472.00 € | ||
| 500mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Nintedanib esylate
CAS:656247-18-6
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and …
Formula:
C31H33N5O4·C2H6O3S
Purity:
99.43% - 99.96%
Color and Shape:
Solid
Molecular weight:
649.76
Ref: TM-T5001
| 5mg | 42.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 83.00 € | ||
| 100mg | 103.00 € | ||
| 200mg | 161.00 € | ||
| 500mg | 310.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
FIIN-2
CAS:1633044-56-0
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 …
Formula:
C35H38N8O4
Purity:
99.34% - 99.65%
Color and Shape:
Crystalline Solid
Molecular weight:
634.73
Ref: TM-T6836
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 197.00 € | ||
| 50mg | 299.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LY2874455
CAS:1254473-64-7
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
Formula:
C21H19Cl2N5O2
Purity:
97.22% - 99.46%
Color and Shape:
Solid
Molecular weight:
444.31
Ref: TM-T2361
| 1mg | 63.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 343.00 € | ||
| 50mg | 510.00 € | ||
| 100mg | 732.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Erdafitinib
CAS:1346242-81-6
Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.
Formula:
C25H30N6O2
Purity:
97% - 99.07%
Color and Shape:
Solid
Molecular weight:
446.54
Ref: TM-T3726
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 221.00 € | ||
| 500mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ASP5878
CAS:1453208-66-6
ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with …
Formula:
C18H19F2N5O4
Purity:
99.8% - 99.86%
Color and Shape:
Solid
Molecular weight:
407.37
Ref: TM-T5473
| 1mg | 65.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 580.00 € | ||
| 100mg | 813.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD4547
CAS:1035270-39-3
AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 …
Formula:
C26H33N5O3
Purity:
99.37% - 99.83%
Color and Shape:
Solid
Molecular weight:
463.57
Ref: TM-T1948
| 2mg | 39.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 111.00 € | ||
| 100mg | 152.00 € | ||
| 200mg | 214.00 € | ||
| 500mg | 361.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
