Fibroblast Growth Factor Receptor (FGFR)
FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.
Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"
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NSC 12
CAS:<p>NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.</p>Formula:C24H34F6O3Purity:99.51%Color and Shape:SolidMolecular weight:484.52Nintedanib
CAS:Formula:C31H33N5O4Purity:>95.0%(T)(HPLC)Color and Shape:White to Yellow to Yellow green powder to crystalMolecular weight:539.64SM27
CAS:<p>SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.</p>Formula:C21H16N2O9S2Purity:98.83%Color and Shape:SolidMolecular weight:504.49(Z)-Orantinib
CAS:<p>(Z)-Orantinib, oral ATP-competitive blocker for Flk-1/KDR, PDGFRβ, FGFR1 (IC50: 2.1, 0.008, 1.2 μM), is a strong antiangiogenic, antitumor drug.</p>Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35PD-161570
CAS:Formula:C26H35Cl2N7OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:532.51FIIN-3
CAS:<p>FIIN-3 is an irreversible inhibitor of FGFR.</p>Formula:C34H36Cl2N8O4Purity:97.63% - 98.92%Color and Shape:SolidMolecular weight:691.61Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64S49076 HCl
CAS:<p>S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3.</p>Formula:C22H18ClN3O5Purity:98%Color and Shape:SolidMolecular weight:439.85Dovitinib lactate
CAS:<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51ON123300
CAS:<p>ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).</p>Formula:C24H27N7OPurity:99.22% - 99.53%Color and Shape:SolidMolecular weight:429.52PRN1371
CAS:<p>PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).</p>Formula:C26H30Cl2N6O4Purity:98.65%Color and Shape:SolidMolecular weight:561.46KHS 101
CAS:<p>KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.</p>Formula:C18H21N5SPurity:99.63%Color and Shape:SolidMolecular weight:339.46SU4984
CAS:<p>SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).</p>Formula:C20H19N3O2Purity:97.20%Color and Shape:SolidMolecular weight:333.38PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Formula:C29H34N6O4S2Purity:97.67% - 98.44%Color and Shape:SolidMolecular weight:594.75Ferulic acid sodium
CAS:<p>Ferulic acid sodium (Sodium ferulic) is an agent used in the treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.</p>Formula:C10H9NaO4Purity:99.58%Color and Shape:White Crystalline PowderMolecular weight:216.16R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Formula:C18H14ClFN4OPurity:98.422%Color and Shape:SolidMolecular weight:356.78Futibatinib
CAS:<p>Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.</p>Formula:C22H22N6O3Purity:97.66% - 99.44%Color and Shape:SolidMolecular weight:418.45GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98Dovitinib lactate hydrate
CAS:<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51
