ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Found 136 products of "ALK"
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CJ-2360
CAS:CJ-2360 is a potent ALK inhibitor, effective on wild-type and various mutants, with IC50 values ranging from 2.2 to 8.9 nM, also targeting 468 kinases.Formula:C27H30FN5O2Color and Shape:SolidMolecular weight:475.56ALK5-IN-30
CAS:ALK5-IN-30 (EX-07) is a potent inhibitor of ALK with inhibitory effects on ALK5 (IC50< 10 nM) and TGFβ-R1 (IC50< 10 nM).Formula:C24H25FN8Color and Shape:SolidMolecular weight:444.51XST-14
CAS:XST-14 is a ULK1 inhibitor.XST-14 induces apoptosis and inhibits the growth of HCC cells.Formula:C16H21NO4Purity:99.84% - 99.84%Color and Shape:SolidMolecular weight:291.34ALK-IN-5
CAS:ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 nM).Formula:C24H25FN6O3Purity:98%Color and Shape:SolidMolecular weight:464.49WY-135
CAS:WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively).Formula:C28H34ClN9O3SPurity:98%Color and Shape:SolidMolecular weight:612.15Ficonalkib
CAS:Ficonalkib is a potent antineoplastic agent that inhibits the Anaplastic Lymphoma Kinase (ALK) tyrosine kinase receptor.Formula:C29H39N7O3SColor and Shape:SolidMolecular weight:565.73ALK2-IN-5
CAS:ALK2-IN-5, a pyrazolopyrimidine compound, serves as an inhibitor of ALK2 and FGFR, targeting disorders linked with their activity, including cancer [1].Formula:C24H32N8O2Color and Shape:SolidMolecular weight:464.56SMU-B
CAS:SMU-B is a well-tolerated c-Met/ALK dual inhibitor.Formula:C26H25Cl2FN4O2Purity:98%Color and Shape:SolidMolecular weight:515.41Con B-1
CAS:ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells .Formula:C38H52ClN7O6SColor and Shape:SolidMolecular weight:770.38ALK5-IN-29
CAS:ALK5-IN-29: selective ALK inhibitor, IC50 ≤ 10 nM, curbs tumor growth, aids in cancer research.Formula:C24H25FN8Color and Shape:SolidMolecular weight:444.51MY10
CAS:MY10, a potent and orally active inhibitor of the receptor protein tyrosine phosphatase (RPTPβ/ζ), effectively reduces binge-like ethanol consumption andFormula:C15H10F6OS2Purity:98.64%Color and Shape:SolidMolecular weight:384.36Ref: TM-T61678
1mg58.00€5mg126.00€10mg197.00€25mg394.00€50mg628.00€100mg982.00€200mg1,314.00€1mL*10mM (DMSO)167.00€Conteltinib
CAS:Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Formula:C32H45N9O3SPurity:98.12% - 99.54%Color and Shape:SolidMolecular weight:635.82Ref: TM-T14997
1mg70.00€5mg150.00€10mg216.00€25mg369.00€50mg517.00€100mg722.00€1mL*10mM (DMSO)205.00€JH-VIII-157-02
CAS:JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.Formula:C28H27N5O2Purity:99.58%Color and Shape:SolidMolecular weight:465.55Ref: TM-T15612
1mg110.00€5mg227.00€10mg339.00€25mg530.00€50mg713.00€100mg982.00€1mL*10mM (DMSO)234.00€TP0427736 hydrochloride
CAS:TP0427736 hydrochloride is a novel and selective ALK5 inhibitor, capable of inhibiting Smad2/3 phosphorylation in A549 cells.Formula:C14H11ClN4S2Purity:98.99%Color and Shape:SolidMolecular weight:334.85ALK/EGFR-IN-2
CAS:ALK/EGFR-IN-2 is a potent dual inhibitor targeting ALK and EGFR, promoting apoptosis and G0/G1 cell cycle arrest in cancer cells.Formula:C27H34ClN7O3SColor and Shape:SolidMolecular weight:572.12ALK/ROS1-IN-1
CAS:ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).Formula:C30H35F3N6O3Purity:98%Color and Shape:SolidMolecular weight:584.63ALK/EGFR-IN-3
CAS:ALK/EGFR-IN-3 is a dual ALK and EGFR inhibitor that demonstrates potent anti-proliferative effects on various cancer cell lines, including H1975, PC9, and Baf3-Formula:C27H34ClN7O3SColor and Shape:SolidMolecular weight:572.12GW-6604
CAS:GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.Formula:C19H14N4Purity:99.6%Color and Shape:SolidMolecular weight:298.34ALK/EGFR-IN-1
CAS:ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their phosphorylation.Formula:C27H34ClN7O3SPurity:98%Color and Shape:SolidMolecular weight:572.12ALK-IN-6
CAS:ALK-IN-6 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK, IC50s: 71 nM, 18.72 nM, and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L).Formula:C26H29ClD3N5O3SPurity:98%Color and Shape:SolidMolecular weight:533.1
