ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Found 136 products of "ALK"
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Alectinib hydrochloride
CAS:Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)Formula:C30H35ClN4O2Purity:99.74% - 99.96%Color and Shape:SolidMolecular weight:519.08Ceritinib
CAS:Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.Formula:C28H36ClN5O3SPurity:98.52% - 99.77%Color and Shape:SolidMolecular weight:558.14Ensartinib
CAS:Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).Formula:C26H27Cl2FN6O3Purity:99.92%Color and Shape:SolidMolecular weight:561.44K02288
CAS:K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.Formula:C20H20N2O4Purity:98% - 99.83%Color and Shape:SolidMolecular weight:352.38AZ 12799734
CAS:AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 with inhibitory effects on BMP and TGFβ for the study of tumours.Formula:C18H18N4O3SPurity:98.23%Color and Shape:SolidMolecular weight:370.43SB-505124 hydrochloride
CAS:SB-505124 hydrochloride (SB505124 hydrochloride) is a TGF-β type I receptor (ALK4, ALK5, ALK7) inhibitor for the study of colorectal cancer.Formula:C20H22ClN3O2Purity:98.71%Color and Shape:SolidMolecular weight:371.86ALK5-IN-79
CAS:ALK5-IN-79 (compound 57), an ALK inhibitor, exhibits anticancer activity by inhibiting the TGF-β1/SMAD signaling pathway. It effectively reduces the production of extracellular matrix (ECM) and collagen deposition. Moreover, ALK5-IN-79 demonstrates satisfactory pharmacokinetic (PK) properties and favorable in vivo tolerance.Formula:C23H27N7OColor and Shape:SolidMolecular weight:417.51ALK2-IN-2
CAS:ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.Formula:C28H27N5O2SPurity:99.86%Color and Shape:SolidMolecular weight:497.61Ref: TM-T10287
1mg44.00€5mg89.00€10mg142.00€25mg216.00€50mg298.00€100mg411.00€200mg560.00€1mL*10mM (DMSO)99.00€EML4-ALK kinase inhibitor 1
CAS:Potent oral EML4-ALK inhibitor with a 1 nM IC50.Formula:C31H48N8O3Purity:99.62%Color and Shape:SolidMolecular weight:580.76Ref: TM-T11184
1mg92.00€5mg200.00€10mg299.00€25mg484.00€50mg658.00€100mg892.00€500mg1,773.00€1mL*10mM (DMSO)256.00€TRK/ALK-IN-1
TRK/ALK-IN-1: Potent dual TRK & ALK inhibitor; IC50s: 2.2nM (TRKA), 9.3nM (ALK WT), 38nM (ALK L1196M); cancer research potential.Formula:C31H35ClF2N8O2SColor and Shape:SolidMolecular weight:657.18Con B-1
CAS:ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells .Formula:C38H52ClN7O6SColor and Shape:SolidMolecular weight:770.38RIPK2-IN-1
CAS:RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 (IC50: 51 nM) and also inhibits ALK2 (IC50: 5 nM).Formula:C23H27N5O3SColor and Shape:SolidMolecular weight:453.56ALK-IN-21
CAS:ALK-IN-21 (B10) inhibits ALK WT (IC50: 4.59nM), L1196M (2.07nM), G1202R (5.95nM); curbs Karpas299, H2228 cell growth; for ALCL research.Formula:C35H45ClN6O6S4Color and Shape:SolidMolecular weight:809.48ALK5-IN-26
CAS:ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 (IC50 ≤ 1 nM).Formula:C24H25FN8Color and Shape:SolidMolecular weight:444.51ALK-IN-22
CAS:ALK-IN-22 suppresses ALK and mutants (IC50: 2.3-3.7 nM), hinders phosphorylation, and induces apoptosis in tumor studies.Formula:C24H24ClN7O2Color and Shape:SolidMolecular weight:477.95OD36
CAS:OD36: Potent RIPK2 inhibitor, IC50=5.3 nM; hinders ALK2 signaling and osteogenesis, KD=37 nM; targets ALK2 ATP pocket.Formula:C16H15ClN4O2Purity:99.45%Color and Shape:SolidMolecular weight:330.77TGFBR1-IN-1
CAS:TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM).Formula:C23H17N5O2SPurity:98%Color and Shape:SolidMolecular weight:427.48OD36 hydrochloride
CAS:OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficientlyFormula:C16H16Cl2N4O2Purity:99.85%Color and Shape:SolidMolecular weight:367.23KRCA-0713
CAS:KRCA-0713 is a ALK inhibitor.Formula:C26H32ClN5O3SPurity:98%Color and Shape:SolidMolecular weight:530.08J-1048
CAS:J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/Formula:C23H17FN6S2Color and Shape:SolidMolecular weight:460.55
