ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
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ML347
CAS:1062368-49-3
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the …
Formula:
C22H16N4O
Purity:
98.3% - ≥95%
Color and Shape:
Solid
Molecular weight:
352.39
Ref: TM-T1943
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 460.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
![5-phenylthieno[2,3-d]pyrimidin-4-amine](https://static.cymitquimica.com/products/TM/thumb/T50042.jpg)
5-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:195193-10-3
5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.
Formula:
C12H9N3S
Purity:
97%
Color and Shape:
Solid
Molecular weight:
227.29
Ref: TM-T50042
| 2mg | 44.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 307.00 € | ||
| 200mg | 439.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RepSox
CAS:446859-33-2
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP …
Formula:
C17H13N5
Purity:
98.8% - 99.62%
Color and Shape:
Solid
Molecular weight:
287.32
Ref: TM-T6337
| 1mg | 35.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 250.00 € | ||
| 500mg | 618.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SM 16
CAS:614749-78-9
SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
Formula:
C25H26N4O3
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
430.5
Ref: TM-T4975
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 616.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
![N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bro…](https://static.cymitquimica.com/products/TM/thumb/T9837.jpg)
N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS:1352608-94-6
Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.
Formula:
C22H18BrN7
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
460.33
Ref: TM-T9837
| 1mg | 96.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 276.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 628.00 € | ||
| 100mg | 844.00 € | ||
| 200mg | 1,130.00 € | ||
| 1mL*10mM (DMSO) | 221.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BIBF0775
CAS:334951-90-5
BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
Formula:
C31H34N4O2
Purity:
99.02% - 99.45%
Color and Shape:
Solid
Molecular weight:
494.63
Ref: TM-T5197
| 1mg | 42.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 130.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 422.00 € | ||
| 200mg | 589.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
A 83-01
CAS:909910-43-6
A 83-01 (ALK5 Inhibitor IV) is a selective inhibitor of TGF-β type I receptor ALK5 …
Formula:
C25H19N5S
Purity:
97% - 98.20%
Color and Shape:
Solid
Molecular weight:
421.52
Ref: TM-T3031
| 5mg | 57.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 254.00 € | ||
| 100mg | 376.00 € | ||
| 500mg | 885.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB-505124
CAS:694433-59-5
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.
Formula:
C20H21N3O2
Purity:
97.19% - 99.92%
Color and Shape:
Solid
Molecular weight:
335.4
Ref: TM-T2462
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 535.00 € | ||
| 500mg | 1,132.00 € | ||
| 1mL*10mM (DMSO) | 139.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Alectinib hydrochloride
CAS:1256589-74-8
Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : …
Formula:
C30H35ClN4O2
Purity:
99.61% - 99.96%
Color and Shape:
Solid
Molecular weight:
519.08
Ref: TM-T8387
| 5mg | 43.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 159.00 € | ||
| 500mg | 369.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HG-14-10-04
CAS:1356962-34-9
HG-14-10-04 is a potent and specific ALK inhibitor.
Formula:
C29H34ClN7O
Purity:
100% - 99.75%
Color and Shape:
Solid
Molecular weight:
532.08
Ref: TM-T4015
| 1mg | 59.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 194.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 493.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB-431542
CAS:301836-41-9
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.
Formula:
C22H16N4O3
Purity:
100% - 99.87%
Color and Shape:
Solid
Molecular weight:
384.39
Ref: TM-T1726
| 5mg | 55.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
R-268712
CAS:879487-87-3
R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type …
Formula:
C20H18FN5O
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
363.39
Ref: TM-T16708
| 1mg | 46.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 393.00 € | ||
| 100mg | 559.00 € | ||
| 200mg | 795.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Blu-782
CAS:2141955-96-4
Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formula:
C31H42N6O4
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
562.7
Ref: TM-T8108
| 1mg | 80.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 454.00 € | ||
| 50mg | 648.00 € | ||
| 100mg | 898.00 € | ||
| 1mL*10mM (DMSO) | 207.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB 525334
CAS:356559-20-1
SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).
Formula:
C21H21N5
Purity:
98.39% - ≥95%
Color and Shape:
Solid
Molecular weight:
343.42
Ref: TM-T1763
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 262.00 € | ||
| 200mg | 310.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LDN-193189 HCl
CAS:1062368-62-0
LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor.
Formula:
C25H22N6·HCl
Purity:
100% - 99.49%
Color and Shape:
Solid
Molecular weight:
442.94
Ref: TM-T6158
| 1mg | 44.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 262.00 € | ||
| 100mg | 393.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Vactosertib Hydrochloride
CAS:1352610-25-3
Vactosertib HCl: oral ATP-competitive ALK5 inhibitor, IC50=12.9 nM; anticancer, antimetastatic, also targets ALK2/4.
Formula:
C22H19ClFN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
435.89
Ref: TM-T15262
| 2mg | 84.00 € | ||
| 5mg | 99.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
A 83-01 sodium salt
CAS:2828431-89-4
A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 …
Formula:
C25H19N5NaS
Color and Shape:
Solid
Molecular weight:
444.51
Ref: TM-T10442
| 500mg | 3,969.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ALK2-IN-2
CAS:2254409-25-9
ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 …
Formula:
C28H27N5O2S
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
497.61
Ref: TM-T10287
| 1mg | 91.00 € | ||
| 2mg | 134.00 € | ||
| 5mg | 215.00 € | ||
| 10mg | 343.00 € | ||
| 25mg | 541.00 € | ||
| 50mg | 742.00 € | ||
| 100mg | 1,028.00 € | ||
| 500mg | 2,103.00 € | ||
| 1mL*10mM (DMSO) | 238.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
OD36
CAS:1638644-62-8
OD36: Potent RIPK2 inhibitor, IC50=5.3 nM; hinders ALK2 signaling and osteogenesis, KD=37 nM; targets ALK2 …
Formula:
C16H15ClN4O2
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
330.77
Ref: TM-T35694
| 1mg | 73.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 384.00 € | ||
| 50mg | 576.00 € | ||
| 100mg | 867.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ALK-IN-5
CAS:2351929-66-1
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 …
Formula:
C24H25FN6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
464.49
Ref: TM-T10283
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
