ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Read more
ZX-29
CAS:2254805-62-2
ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; …
Formula:
C23H28ClN7O3S
Purity:
98.32%
Color and Shape:
Solid
Molecular weight:
518.03
Ref: TM-T13416
| 1mg | 91.00 € | ||
| 5mg | 228.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 613.00 € | ||
| 50mg | 838.00 € | ||
| 100mg | 1,107.00 € | ||
| 1mL*10mM (DMSO) | 293.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
CEP-28122 mesylate salt (1022958-60-6 free base)
CEP-28122 mesylate salt (1022958-60-6 free base) is a highly selective orally active ALK inhibitor (IC50: …
Formula:
C29H39ClN6O6S
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
635.17
Ref: TM-T10759
| 1mg | 45.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 266.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
INCB-000928
CAS:2173389-57-4
Zilurgisertib (INCB-000928) is a selective and potent ALK 2 inhibitor for the study of cancer …
Formula:
C30H38N4O3
Purity:
98.93%
Color and Shape:
Liquid
Molecular weight:
502.65
Ref: TM-T77726
| 1mg | 200.00 € | ||
| 5mg | 505.00 € | ||
| 10mg | 814.00 € | ||
| 25mg | 1,576.00 € | ||
| 50mg | 2,579.00 € | ||
| 1mL*10mM (DMSO) | 558.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ALK-IN-26
CAS:2447607-85-2
ALK-IN-26 is an ALK inhibitor with potential anticancer activity.ALK-IN-26 shows antiproliferative activity against glioblastoma.
Formula:
C24H23NO3S
Purity:
99.91%
Color and Shape:
Soild
Molecular weight:
405.51
Ref: TM-T77754
| 1mg | 41.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 517.00 € | ||
| 500mg | 1,100.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
LDN-193189 2HCl
CAS:1435934-00-1
LDN-193189 2HCl inhibits BMP signaling (ALK1/2/3/6), IC50: 0.8-16.7 nM; selective over TGF-β by 200-fold in …
Formula:
C25H24Cl2N6
Purity:
99.78%
Color and Shape:
Liquid
Molecular weight:
479.4
Ref: TM-T35348
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 328.00 € | ||
| 500mg | 782.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SB-505124 hydrochloride
CAS:356559-13-2
SB-505124 hydrochloride (SB505124 hydrochloride) is a TGF-β type I receptor (ALK4, ALK5, ALK7) inhibitor for …
Formula:
C20H22ClN3O2
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
371.86
Ref: TM-T21637
| 1mg | 40.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 303.00 € | ||
| 100mg | 451.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AZ 12799734
CAS:1117684-36-2
AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 …
Formula:
C18H18N4O3S
Purity:
98.23%
Color and Shape:
Liquid
Molecular weight:
370.43
Ref: TM-T35896
| 5mg | 110.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 373.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 869.00 € | ||
| 500mg | 1,735.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
EW-7195
CAS:1352609-28-9
EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, …
Formula:
C23H18N8
Purity:
98.76%
Color and Shape:
Liquid
Molecular weight:
406.44
Ref: TM-T38752
| 1mg | 128.00 € | ||
| 2mg | 182.00 € | ||
| 5mg | 307.00 € | ||
| 10mg | 525.00 € | ||
| 25mg | 1,044.00 € | ||
| 50mg | 1,698.00 € | ||
| 100mg | 2,700.00 € | ||
| 1mL*10mM (DMSO) | 343.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CH5424802 analog
CAS:1256577-71-5
CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.
Formula:
C28H30N4O2
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
454.56
Ref: TM-T9224
| 1mg | 131.00 € | ||
| 5mg | 287.00 € | ||
| 10mg | 430.00 € | ||
| 25mg | 709.00 € | ||
| 50mg | 996.00 € | ||
| 100mg | 1,347.00 € | ||
| 1mL*10mM (DMSO) | 343.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
DMH-1
CAS:1206711-16-1
DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent …
Formula:
C24H20N4O
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
380.44
Ref: TM-T1942
| 5mg | 62.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 428.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
ALK kinase inhibitor-1
CAS:1462949-64-9
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.
Formula:
C28H32FN5O3S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
537.65
Ref: TM-T6409
| 5mg | 48.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 158.00 € | ||
| 100mg | 233.00 € | ||
| 200mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
AZD-3463
CAS:1356962-20-3
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R …
Formula:
C24H25ClN6O
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
448.95
Ref: TM-T1967
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
K02288
CAS:1431985-92-0
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
Formula:
C20H20N2O4
Purity:
98% - 99.81%
Color and Shape:
Solid
Molecular weight:
352.38
Ref: TM-T1914
| 2mg | 44.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 403.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
CEP-28122
CAS:1022958-60-6
CEP-28122 is a highly potent and selective orally active ALK inhibitor.
Formula:
C28H35ClN6O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
539.07
Ref: TM-T2612
| 1mg | 54.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 367.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
Vactosertib
CAS:1352608-82-2
Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.
Formula:
C22H18FN7
Purity:
98.85% - 99.81%
Color and Shape:
Solid
Molecular weight:
399.42
Ref: TM-T6496
| 1g | 1,142.00 € | ||
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 540.00 € | ||
| 500mg | 853.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
LDN-214117
CAS:1627503-67-6
LDN-214117 is a potent and selective ALK2 inhibitor.
Formula:
C25H29N3O3
Purity:
100% - 99.85%
Color and Shape:
Solid
Molecular weight:
419.52
Ref: TM-T1944
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 290.00 € | ||
| 100mg | 448.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
LDN193189
CAS:1062368-24-4
LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.
Formula:
C25H22N6
Purity:
98% - 99.86%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T1935
| 2mg | 48.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 328.00 € | ||
| 200mg | 488.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
LDN-212854
CAS:1432597-26-6
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the …
Formula:
C25H22N6
Purity:
98% - 99.38%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T1900
| 1mg | 54.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 735.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
A 77-01
CAS:607737-87-1
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 …
Formula:
C18H14N4
Purity:
99.31% - ≥95%
Color and Shape:
Solid
Molecular weight:
286.33
Ref: TM-T2098
| 1mg | 48.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 495.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
GW788388
CAS:452342-67-5
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor …
Formula:
C25H23N5O2
Purity:
98.03% - 98.79%
Color and Shape:
Solid
Molecular weight:
425.48
Ref: TM-T1800
| 5mg | 63.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 261.00 € | ||
| 100mg | 384.00 € | ||
| 500mg | 894.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
