c-Fms
c-Fms inhibitors target the Colony Stimulating Factor-1 Receptor (c-Fms), a tyrosine kinase involved in the regulation of macrophages and other immune cells. c-Fms signaling plays a role in the proliferation, differentiation, and survival of these cells. Dysregulation of c-Fms is associated with diseases such as cancer, inflammatory conditions, and osteoporosis. At CymitQuimica, we offer c-Fms inhibitors to support your research in immunology, oncology, and inflammatory diseases.
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Lenzilumab
CAS:1229575-09-0
Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T76751
| 1mg | 188.00 € | ||
| 5mg | 476.00 € | ||
| 10mg | 751.00 € | ||
| 25mg | 1,134.00 € | ||
| 50mg | 1,508.00 € |
Estimated delivery in United States, on Monday 12 May 2025
CSF1R Protein, Human, Recombinant (mFc)
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.
Color and Shape:
Lyophilized Powder
Molecular weight:
81.5 kDa (predicted)
Ref: TM-TMPY-05264
| 1mg | 1,911.00 € | ||
| 100µg | 306.00 € |
Estimated delivery in United States, on Monday 12 May 2025
CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Purity:
SDS-PAGE: 97.7%; SEC-HPLC: 99.7%
Color and Shape:
Lyophilized Powder
Molecular weight:
56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01037
| 100µg | 235.00 € | ||
| 200µg | 416.00 € |
Estimated delivery in United States, on Monday 12 May 2025
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with …
Color and Shape:
Lyophilized Powder
Molecular weight:
83.04 kDa (predicted); 110.87 kDa (reducing conditions)
Ref: TM-TMPY-06389
| 20µg | 475.00 € | ||
| 100µg | 1,083.00 € |
Estimated delivery in United States, on Monday 12 May 2025
CSF1R Protein, Human, Recombinant (His & Avi)
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi …
Color and Shape:
Lyophilized Powder
Molecular weight:
57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00414
| 1mg | 1,569.00 € | ||
| 100µg | 238.00 € | ||
| 500µg | 944.00 € |
Estimated delivery in United States, on Monday 12 May 2025
AZD7507
CAS:1041852-85-0
AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.
Formula:
C23H27FN6O3
Purity:
98.01% - 99.09%
Color and Shape:
Solid
Molecular weight:
454.5
Ref: TM-T14380
| 1mg | 52.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 442.00 € | ||
| 100mg | 615.00 € | ||
| 200mg | 832.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PF 477736
CAS:952021-60-2
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) …
Formula:
C22H25N7O2
Purity:
98.34% - 99.62%
Color and Shape:
Solid
Molecular weight:
419.48
Ref: TM-T6028
| 2mg | 49.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Ki20227
CAS:623142-96-1
Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).
Formula:
C24H24N4O5S
Purity:
97.16% - 99.37%
Color and Shape:
Solid
Molecular weight:
480.54
Ref: TM-T4315
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 154.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 464.00 € | ||
| 100mg | 740.00 € | ||
| 200mg | 1,008.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Nampt-IN-1
CAS:1698878-14-6
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with …
Formula:
C20H25N3O5S
Purity:
96.82% - 99.4%
Color and Shape:
Solid
Molecular weight:
419.49
Ref: TM-T4376
| 1mg | 39.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 638.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 16 May 2025
OSI-930
CAS:728033-96-3
OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.
Formula:
C22H16F3N3O2S
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
443.44
Ref: TM-T2624
| 1mg | 51.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 263.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 612.00 € | ||
| 200mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Friday 16 May 2025
cFMS Receptor Inhibitor II
CAS:959860-85-6
cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor
Formula:
C23H20N4O
Purity:
99.80%
Color and Shape:
Solid
Molecular weight:
368.43
Ref: TM-T5586
| 1mg | 49.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 154.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 547.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Friday 16 May 2025
GW786034B
CAS:635702-64-6
Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in …
Formula:
C21H23N7O2S·HCl
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
473.98
Ref: TM-T6930
| 10mg | 52.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 140.00 € | ||
| 200mg | 229.00 € | ||
| 500mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PRN1371
CAS:1802929-43-6
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 …
Formula:
C26H30Cl2N6O4
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
561.46
Ref: TM-TQ0015
| 1mg | 81.00 € | ||
| 2mg | 105.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 520.00 € | ||
| 50mg | 748.00 € | ||
| 100mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 212.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PLX5622
CAS:1303420-67-8
PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination …
Formula:
C21H19F2N5O
Purity:
98% - 99.89%
Color and Shape:
Solid
Molecular weight:
395.41
Ref: TM-T7100
| 5mg | 96.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 308.00 € | ||
| 50mg | 510.00 € | ||
| 100mg | 617.00 € | ||
| 500mg | 1,311.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Vimseltinib
CAS:1628606-05-2
Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 …
Formula:
C23H25N7O2
Purity:
99.05% - 99.57%
Color and Shape:
Solid
Molecular weight:
431.49
Ref: TM-T10652
| 1mg | 92.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 533.00 € | ||
| 50mg | 727.00 € | ||
| 100mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 215.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Linifanib
CAS:796967-16-3
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), …
Formula:
C21H18FN5O
Purity:
98% - 98.24%
Color and Shape:
Solid
Molecular weight:
375.4
Ref: TM-T2514
| 5mg | 50.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 274.00 € | ||
| 200mg | 505.00 € | ||
| 500mg | 815.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Pexidartinib
CAS:1029044-16-3
Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of …
Formula:
C20H15ClF3N5
Purity:
98.34% - 99.51%
Color and Shape:
Solid
Molecular weight:
417.81
Ref: TM-T2115
| 5mg | 48.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 154.00 € | ||
| 200mg | 202.00 € | ||
| 500mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 16 May 2025
AZ304
CAS:942507-42-8
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and …
Formula:
C27H25N5O2
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
451.52
Ref: TM-T5172
| 10mg | 42.00 € | ||
| 25mg | 65.00 € | ||
| 50mg | 97.00 € | ||
| 100mg | 156.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Friday 16 May 2025
PLX5622 hemifumarate
PLX5622 hemifumarate: selective CSF1R inhibitor (IC50: 0.016 μM, Ki: 5.9 nM), brain-penetrant, oral, clears microglia …
Formula:
C25H23F2N5O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
453.45
Ref: TM-T12505
| 200mg | 1,109.00 € |
Estimated delivery in United States, on Friday 16 May 2025
Sotuletinib
CAS:953769-46-5
Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its …
Formula:
C20H22N4O3S
Purity:
97.43% - 99.82%
Color and Shape:
Solid
Molecular weight:
398.48
Ref: TM-T6119
| 1mg | 37.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 216.00 € | ||
| 100mg | 378.00 € | ||
| 500mg | 868.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 16 May 2025
