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  6. Tyrosine Kinase/Adaptors
  7. Trk receptor
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Trk receptor

Trk receptor inhibitors target the Tropomyosin receptor kinases (Trk), a family of receptor tyrosine kinases that play a significant role in the development and function of the nervous system. Trk receptors are involved in neurotrophin signaling, which is essential for the survival, differentiation, and growth of neurons. Dysregulation of Trk signaling is associated with neurological disorders and certain cancers. At CymitQuimica, we offer Trk receptor inhibitors to support your research in neurobiology, oncology, and neurodegenerative diseases.

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products per page. 50 products on this category.

BrandProduct dataPurityPrice rangeEstimated delivery
Targetmol logo
GNF-5837
REF: TM-T6097CAS: 1033769-28-6 		96.17% - 99.29%50.00 €~657.00 €Tue 22 Apr 25
Targetmol logo
DS-1205
REF: TM-T9123CAS: 1855860-24-0 		99.28%106.00 €~938.00 €Tue 22 Apr 25
Targetmol logo
GW 441756
REF: TM-T6052CAS: 504433-23-2 		97.73% - 99.8%56.00 €~807.00 €Tue 22 Apr 25
Targetmol logo
ONO-7475
REF: TM-T8327CAS: 1646839-59-9 		98.74%63.00 €~747.00 €Tue 22 Apr 25
Targetmol logo
ANA-12
REF: TM-T2359CAS: 219766-25-3 		99.28% - 99.87%40.00 €~1,111.00 €Tue 22 Apr 25
Targetmol logo
7,8-Dihydroxyflavone
REF: TM-T2816CAS: 38183-03-8 		98.37% - 99.81%35.00 €~88.00 €Tue 22 Apr 25
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Repotrectinib
REF: TM-T4071CAS: 1802220-02-5 		100% - 99.92%49.00 €~688.00 €Tue 22 Apr 25
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Larotrectinib sulfate
REF: TM-T6880CAS: 1223405-08-0 		98.62% - 99.69%39.00 €~658.00 €Tue 22 Apr 25
Targetmol logo
LM22B-10
REF: TM-T4496CAS: 342777-54-2 		98.18%40.00 €~707.00 €Tue 22 Apr 25
Targetmol logo
Sitravatinib
REF: TM-T4349CAS: 1123837-84-2 		98.9% - 99.74%51.00 €~845.00 €Tue 22 Apr 25
Targetmol logo
BMS-754807
REF: TM-T2349CAS: 1001350-96-4 		98.86%49.00 €~772.00 €Tue 20 May 25
Targetmol logo
TRK-IN-23
REF: TM-T78968CAS: 2924344-29-4 		98%907.00 €~2,375.00 €Tue 03 Jun 25
Targetmol logo
TRK II-IN-1
REF: TM-T73033CAS: 2904690-41-9 		98%907.00 €~2,375.00 €Tue 03 Jun 25
Targetmol logo
Protein kinase inhibitor 5
REF: TM-T79125CAS: 2278204-94-5 		98%907.00 €~2,375.00 €Tue 03 Jun 25
Targetmol logo
Tavilermide
REF: TM-T17000CAS: 263251-78-1 		98.98%143.00 €~2,375.00 €Tue 03 Jun 25
Targetmol logo
TrkA-IN-1
REF: TM-T13208CAS: 1680179-43-4 		98%118.00 €~2,062.00 €Tue 03 Jun 25
Targetmol logo
Trk-IN-4
REF: TM-T17169CAS: 1799788-94-5 		98%To inquireTue 03 Jun 25
Targetmol logo
ENT-C225
REF: TM-T73397CAS: 2919962-53-9 		99.16% - 99.16%185.00 €~1,415.00 €Tue 17 Jun 25
Targetmol logo
PF-06733804
REF: TM-T13207CAS: 1873373-33-1 		98%1,094.00 €~2,945.00 €Tue 17 Jun 25
Targetmol logo
TrkB-IN-1
REF: TM-T79011CAS: 1609067-49-3 		98%To inquireTue 17 Jun 25
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GNF-5837
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GNF-5837

CAS:1033769-28-6
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
Formula:
C28H21F4N5O2
Purity:
96.17% - 99.29%
Color and Shape:
Solid
Molecular weight:
535.49

Ref: TM-T6097

5mg50.00 €
10mg85.00 €
25mg124.00 €
50mg188.00 €
100mg311.00 €
200mg404.00 €
500mg657.00 €
1mL*10mM (DMSO)56.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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DS-1205
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DS-1205

CAS:1855860-24-0
DS-1205: AXL kinase inhibitor (IC50=1.3 nM), also targets MER, MET, TRKA (IC50s: 63, 104, 407 …
Formula:
C41H42FN5O7
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
735.8

Ref: TM-T9123

1mg106.00 €
5mg259.00 €
10mg378.00 €
25mg702.00 €
50mg938.00 €
1mL*10mM (DMSO)283.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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GW 441756
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GW 441756

CAS:504433-23-2
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of …
Formula:
C17H13N3O
Purity:
97.73% - 99.8%
Color and Shape:
Solid
Molecular weight:
275.3

Ref: TM-T6052

5mg56.00 €
10mg88.00 €
25mg153.00 €
50mg225.00 €
100mg341.00 €
500mg807.00 €
1mL*10mM (DMSO)63.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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ONO-7475
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ONO-7475

CAS:1646839-59-9
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
Formula:
C32H26N4O6
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
562.57

Ref: TM-T8327

1mg63.00 €
5mg137.00 €
10mg210.00 €
25mg358.00 €
50mg532.00 €
100mg747.00 €
1mL*10mM (DMSO)169.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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ANA-12
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ANA-12

CAS:219766-25-3
ANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.
Formula:
C22H21N3O3S
Purity:
99.28% - 99.87%
Color and Shape:
Solid
Molecular weight:
407.49

Ref: TM-T2359

1mg40.00 €
2mg51.00 €
5mg79.00 €
10mg119.00 €
25mg190.00 €
50mg354.00 €
100mg522.00 €
500mg1,111.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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7,8-Dihydroxyflavone
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7,8-Dihydroxyflavone

CAS:38183-03-8
7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula …
Formula:
C15H10O4
Purity:
98.37% - 99.81%
Color and Shape:
Solid
Molecular weight:
254.24

Ref: TM-T2816

10mg35.00 €
50mg74.00 €
100mg88.00 €
1mL*10mM (DMSO)59.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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discount label
Repotrectinib
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Repotrectinib

CAS:1802220-02-5
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01/5.3/1.08/1.26 nM for WT ALK, …
Formula:
C18H18FN5O2
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
355.37

Ref: TM-T4071

1mg49.00 €
2mg70.00 €
5mg96.00 €
10mg169.00 €
25mg296.00 €
50mg474.00 €
100mg688.00 €
1mL*10mM (DMSO)100.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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discount label
Larotrectinib sulfate
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Larotrectinib sulfate

CAS:1223405-08-0
Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor …
Formula:
C21H22F2N6O2·H2O4S
Purity:
98.62% - 99.69%
Color and Shape:
Solid
Molecular weight:
526.51

Ref: TM-T6880

2mg39.00 €
5mg57.00 €
10mg93.00 €
25mg131.00 €
50mg163.00 €
100mg274.00 €
500mg658.00 €
1mL*10mM (DMSO)66.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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discount label
LM22B-10
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LM22B-10

CAS:342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and …
Formula:
C27H33ClN2O4
Purity:
98.18%
Color and Shape:
Solid
Molecular weight:
485.01

Ref: TM-T4496

1mg40.00 €
5mg87.00 €
10mg137.00 €
25mg283.00 €
50mg445.00 €
100mg707.00 €
1mL*10mM (DMSO)133.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
+ info
discount label
Sitravatinib
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Sitravatinib

CAS:1123837-84-2
Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, …
Formula:
C33H29F2N5O4S
Purity:
98.9% - 99.74%
Color and Shape:
Solid
Molecular weight:
629.68

Ref: TM-T4349

5mg51.00 €
10mg79.00 €
25mg137.00 €
50mg210.00 €
100mg338.00 €
200mg535.00 €
500mg845.00 €
1mL*10mM (DMSO)72.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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discount label
BMS-754807
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BMS-754807

CAS:1001350-96-4
BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.
Formula:
C23H24FN9O
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
461.49

Ref: TM-T2349

1mg49.00 €
2mg70.00 €
5mg96.00 €
10mg166.00 €
25mg328.00 €
50mg537.00 €
100mg772.00 €
1mL*10mM (DMSO)116.00 €
Estimated delivery in United States, on Tuesday 20 May 2025
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discount label
TRK-IN-23
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TRK-IN-23

CAS:2924344-29-4
TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 …
Formula:
C20H17FN4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
364.37

Ref: TM-T78968

25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Tuesday 3 Jun 2025
+ info
discount label
TRK II-IN-1
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TRK II-IN-1

CAS:2904690-41-9
TRK II-IN-1: potent type II TRK inhibitor; IC50s: TRKA (3.3 nM), TRKB (6.4 nM), TRKC …
Formula:
C29H31F3N8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
564.6

Ref: TM-T73033

25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Tuesday 3 Jun 2025
+ info
discount label
Protein kinase inhibitor 5
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Protein kinase inhibitor 5

CAS:2278204-94-5
Protein kinase inhibitor 5 is a potent inhibitor of TRK-A, demonstrating an IC50 of 1.8 …
Formula:
C29H31F2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
531.6

Ref: TM-T79125

25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Tuesday 3 Jun 2025
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discount label
Tavilermide
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Tavilermide

CAS:263251-78-1
Tavilermide (MIM-D3) is a selective TrkA agonist, a cyclic mimetic, which can be used to …
Formula:
C24H32N6O11
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
580.54

Ref: TM-T17000

5mg424.00 €
25mg1,444.00 €
50mg1,882.00 €
100mg2,375.00 €
Estimated delivery in United States, on Tuesday 3 Jun 2025
+ info
discount label
TrkA-IN-1
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TrkA-IN-1

CAS:1680179-43-4
TrkA-IN-1 is a potent and selective inhibitor of Tropomyosin-related kinase A (TrkA) (IC50: 99 nM …
Formula:
C25H20N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
392.45

Ref: TM-T13208

25mg1,045.00 €
50mg1,359.00 €
100mg2,062.00 €
Estimated delivery in United States, on Tuesday 3 Jun 2025
+ info
discount label
Trk-IN-4
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Trk-IN-4

CAS:1799788-94-5
Trk-IN-4 is an effective pan-Trk inhibitor in cell-based assays (IC50s: 1.9 nM, 2.6 nM, and …
Formula:
C24H23F4N5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
521.46

Ref: TM-T17169

1mg40.00 €
2mgTo inquire
Estimated delivery in United States, on Tuesday 3 Jun 2025
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ENT-C225
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ENT-C225

CAS:2919962-53-9
ENT-C225 is a potent TrkB neurotrophin receptor (TrkBR) activator with neuroprotective activity for the study …
Formula:
C26H40N4O5
Purity:
99.16% - 99.16%
Color and Shape:
Liquid
Molecular weight:
488.62

Ref: TM-T73397

1mg185.00 €
5mg459.00 €
10mg657.00 €
25mg1,026.00 €
50mg1,415.00 €
Estimated delivery in United States, on Tuesday 17 Jun 2025
+ info
discount label
PF-06733804
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PF-06733804

CAS:1873373-33-1
PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, …
Formula:
C20H19F5N4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
474.38

Ref: TM-T13207

25mg1,730.00 €
50mg2,262.00 €
100mg2,945.00 €
Estimated delivery in United States, on Tuesday 17 Jun 2025
+ info
discount label
TrkB-IN-1
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TrkB-IN-1

CAS:1609067-49-3
TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) …
Formula:
C19H16N2O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
368.34

Ref: TM-T79011

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 17 Jun 2025
+ info
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