Trk receptor
Trk receptor inhibitors target the Tropomyosin receptor kinases (Trk), a family of receptor tyrosine kinases that play a significant role in the development and function of the nervous system. Trk receptors are involved in neurotrophin signaling, which is essential for the survival, differentiation, and growth of neurons. Dysregulation of Trk signaling is associated with neurological disorders and certain cancers. At CymitQuimica, we offer Trk receptor inhibitors to support your research in neurobiology, oncology, and neurodegenerative diseases.
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ANA-12
CAS:219766-25-3
ANA-12 is a potent and selective TrkB antagonist with anxiolytic and antidepressant activity in mice.
Formula:
C22H21N3O3S
Purity:
99.28% - 99.87%
Color and Shape:
Solid
Molecular weight:
407.49
Ref: TM-T2359
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 512.00 € | ||
| 500mg | 1,087.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Milciclib
CAS:802539-81-7
Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. …
Formula:
C25H32N8O
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
460.57
Ref: TM-T6081
| 1mg | 91.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 307.00 € | ||
| 25mg | 519.00 € | ||
| 50mg | 748.00 € | ||
| 100mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
LM22A-4
CAS:37988-18-4
LM22A-4: BDNF mimetic, TrkB agonist, IC50=47 nM (fluorescence anisotropy).
Formula:
C15H21N3O6
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
339.34
Ref: TM-T7568
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 444.00 € | ||
| 500mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Altiratinib
CAS:1345847-93-9
Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block …
Formula:
C26H21F3N4O4
Purity:
98.98% - 99.39%
Color and Shape:
Solid
Molecular weight:
510.46
Ref: TM-T2054
| 5mg | 52.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 313.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Larotrectinib
CAS:1223403-58-4
Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective …
Formula:
C21H22F2N6O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
428.44
Ref: TM-T5995
| 1mg | 39.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 369.00 € | ||
| 500mg | 849.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
CH7057288
CAS:2095616-82-1
CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, …
Formula:
C32H31N3O5S
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
569.67
Ref: TM-T5635
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 517.00 € | ||
| 100mg | 728.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
7,8-Dihydroxyflavone
CAS:38183-03-8
7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula …
Formula:
C15H10O4
Purity:
98.37% - 99.47%
Color and Shape:
Solid
Molecular weight:
254.24
Ref: TM-T2816
| 10mg | 35.00 € | ||
| 50mg | 73.00 € | ||
| 100mg | 87.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Larotrectinib sulfate
CAS:1223405-08-0
Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor …
Formula:
C21H22F2N6O2·H2O4S
Purity:
98.62% - 99.69%
Color and Shape:
Solid
Molecular weight:
526.51
Ref: TM-T6880
| 2mg | 39.00 € | ||
| 5mg | 58.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 165.00 € | ||
| 100mg | 277.00 € | ||
| 500mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BMS-754807
CAS:1001350-96-4
BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.
Formula:
C23H24FN9O
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
461.49
Ref: TM-T2349
| 1mg | 49.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 321.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 755.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Friday 10 Jan 2025
Tavilermide
CAS:263251-78-1
Tavilermide (MIM-D3) is a selective TrkA agonist, a cyclic mimetic, which can be used to …
Formula:
C24H32N6O11
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
580.54
Ref: TM-T17000
| 5mg | 419.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,865.00 € | ||
| 100mg | 2,367.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
TRK II-IN-1
CAS:2904690-41-9
TRK II-IN-1: potent type II TRK inhibitor; IC50s: TRKA (3.3 nM), TRKB (6.4 nM), TRKC …
Formula:
C29H31F3N8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
564.6
Ref: TM-T73033
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
TRK-IN-23
CAS:2924344-29-4
TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 …
Formula:
C20H17FN4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
364.37
Ref: TM-T78968
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Protein kinase inhibitor 5
CAS:2278204-94-5
Protein kinase inhibitor 5 is a potent inhibitor of TRK-A, demonstrating an IC50 of 1.8 …
Formula:
C29H31F2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
531.6
Ref: TM-T79125
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Trk-IN-4
CAS:1799788-94-5
Trk-IN-4 is an effective pan-Trk inhibitor in cell-based assays (IC50s: 1.9 nM, 2.6 nM, and …
Formula:
C24H23F4N5O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
521.46
Ref: TM-T17169
| 1mg | 40.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Friday 24 Jan 2025
TrkA-IN-1
CAS:1680179-43-4
TrkA-IN-1 is a potent and selective inhibitor of Tropomyosin-related kinase A (TrkA) (IC50: 99 nM …
Formula:
C25H20N4O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
392.45
Ref: TM-T13208
| 25mg | 1,021.00 € | ||
| 50mg | 1,354.00 € | ||
| 100mg | 2,055.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Type II TRK inhibitor 1
CAS:2937543-72-9
Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) …
Formula:
C35H33F3N8O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
670.68
Ref: TM-T72289
| 5mg | 1,290.00 € | ||
| 50mg | 2,618.00 € | ||
| 100mg | 3,484.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
Paltimatrectinib
CAS:2353522-15-1
Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the …
Formula:
C20H15F5N6
Purity:
99.96%
Color and Shape:
Liquid
Molecular weight:
434.37
Ref: TM-T62447
| 1mg | 185.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
TrkB-IN-1
CAS:1609067-49-3
TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) …
Formula:
C19H16N2O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
368.34
Ref: TM-T79011
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
TRK-IN-24
CAS:2937544-01-7
TRK-IN-24 (compound 10g) is a selective inhibitor of Trk receptors, effectively targeting TRKA, TRKC, and …
Formula:
C39H45N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
659.82
Ref: TM-T79706
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 7 Feb 2025
PF-06733804
CAS:1873373-33-1
PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, …
Formula:
C20H19F5N4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
474.38
Ref: TM-T13207
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Friday 7 Feb 2025
