VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 252 products for "VEGFR".
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VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formula:C29H29ClF3N7OSPurity:99.95%Color and Shape:SolidMolecular weight:616.1(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurity:99.63% - 99.74%Color and Shape:SolidMolecular weight:329.17Tyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formula:C16H14N2O2Purity:98.47%Color and Shape:SolidMolecular weight:266.29VEGFR-2-IN-37
CAS:VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formula:C18H16N2O2SPurity:98%Color and Shape:SolidMolecular weight:324.4Brolucizumab
CAS:Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaVEGFR-2-IN-9
CAS:VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Formula:C23H25N3O3Purity:97.19%Color and Shape:SolidMolecular weight:391.46TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Formula:C26H27Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:512.43VEGFR2-IN-3
CAS:VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].Formula:C26H28ClN5O4Purity:98%Color and Shape:SolidMolecular weight:509.98VEGFR-2-IN-38
CAS:VEGFR-2-IN-38 (compound 3) acts as a potential inhibitor of the vascular endothelial growth factor receptor-2 [1].Formula:C17H12N4SColor and Shape:SolidMolecular weight:304.37VEGFR-2-IN-65
CAS:VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.Formula:C21H18N2O3Color and Shape:SolidMolecular weight:346.379VEGFR/PDGFR-IN-1
CAS:VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.Formula:C17H21N5O3Color and Shape:SolidMolecular weight:343.38VEGFR2-IN-1
CAS:VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.Formula:C22H18N6SPurity:98.15%Color and Shape:SolidMolecular weight:398.48
