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VEGFR

VEGFR

VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 268 products of "VEGFR"

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  • GW843682X

    CAS:
    <p>GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).</p>
    Formula:C22H18F3N3O4S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:477.46
  • CP-547632

    CAS:
    <p>CP-547632 is an oral ATP-competitive inhibitor of VEGFR-2/FGF kinase with IC50s of 11/9 nM, highly selective, has antitumor activity.</p>
    Formula:C20H24BrF2N5O3S
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:532.4
  • DMH4

    CAS:
    <p>DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.</p>
    Formula:C24H24N4O2
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:400.47
  • AMG-Tie2-1

    CAS:
    <p>AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.</p>
    Formula:C25H20F3N5O2
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:479.45
  • VEGFR-2-IN-6

    CAS:
    <p>VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].</p>
    Formula:C20H21N7O2S
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:423.49
  • MMPP

    CAS:
    <p>MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.</p>
    Formula:C17H18O3
    Purity:99.31% - 99.83%
    Color and Shape:Solid
    Molecular weight:270.32
  • Naphazoline

    CAS:
    <p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>
    Formula:C14H14N2
    Purity:99.79%
    Color and Shape:White Crystalline Powder Solid
    Molecular weight:210.27
  • Ansornitinib

    CAS:
    <p>Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.</p>
    Formula:C30H32N6O4
    Color and Shape:Solid
    Molecular weight:540.61
  • CGP60474

    CAS:
    <p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>
    Formula:C18H18ClN5O
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:355.82
  • AMPK-IN-3

    CAS:
    <p>AMPK-IN-3: potent, selective AMPK (α2/α1) &amp; KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.</p>
    Formula:C25H33N5O3
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:451.56
  • VEGFR-3-IN-1

    CAS:
    <p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>
    Formula:C29H29ClF3N7OS
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:616.1
  • Pz-1

    CAS:
    <p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>
    Formula:C26H26N6O2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:454.52
  • Chiauranib

    CAS:
    <p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>
    Formula:C27H21N3O3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:435.47
  • (Z)-FeCP-oxindole

    CAS:
    <p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>
    Formula:C19H15FeNO
    Purity:99.63% - 99.84%
    Color and Shape:Solid
    Molecular weight:329.17
  • (E)-FeCP-oxindole

    CAS:
    <p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂,IC50 为 214 nM。</p>
    Formula:C19H15FeNO
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:329.17
  • Tyrphostin AG1433

    CAS:
    <p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>
    Formula:C16H14N2O2
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:266.29
  • TIE-2/VEGFR-2 kinase-IN-5

    CAS:
    <p>TIE-2/VEGFR-2 kinase-IN-5 is a TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor commonly used in biomedical research related to angiogenesis.</p>
    Formula:C21H13F6N5O2
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:481.35
  • Brolucizumab

    CAS:
    <p>Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.</p>
    Purity:95%
    Color and Shape:Liquid
  • TG 100572 Hydrochloride

    CAS:
    <p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>
    Formula:C26H27Cl2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:512.43
  • AKB-6899

    CAS:
    <p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>
    Formula:C14H11FN2O4
    Purity:97.87%
    Color and Shape:Solid
    Molecular weight:290.25