VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 256 products for "VEGFR".
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PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purity:98.45% - 99.93%Color and Shape:SolidMolecular weight:319.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.Formula:C17H16N2OPurity:>99.99%Color and Shape:SolidMolecular weight:264.32Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.Formula:C15H14N2OPurity:99.67% - 99.84%Color and Shape:Yellow SolidMolecular weight:238.28ZM 306416
CAS:ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).Formula:C16H13ClFN3O2Purity:99.88% - ≥95%Color and Shape:SolidMolecular weight:333.74Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purity:99.52%Color and Shape:SolidMolecular weight:346.81Sodium taurocholate
CAS:Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.Formula:C26H44NO7S·NaPurity:95% - 99.86%Color and Shape:White PowderMolecular weight:537.69JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purity:97.08%Color and Shape:White SolidMolecular weight:364.79Ref: TM-T22349
1mg38.00€5mg78.00€1mL*10mM (DMSO)84.00€10mg103.00€25mg172.00€50mg250.00€100mg338.00€200mg464.00€Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:482.82Ref: TM-T1792
5mg34.00€1mL*10mM (DMSO)35.00€10mg49.00€25mg75.00€50mg90.00€100mg137.00€200mg175.00€500mg294.00€Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€1mL*10mM (DMSO)90.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:98.13%Color and Shape:Yellow SolidMolecular weight:442.48MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formula:C26H20FN5O2S2Purity:98.06% - 98.68%Color and Shape:White SolidMolecular weight:517.6R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Formula:C18H14ClFN4OPurity:98.42%Color and Shape:SolidMolecular weight:356.78Ref: TM-TQ0317
1mg39.00€2mg52.00€5mg84.00€1mL*10mM (DMSO)93.00€10mg130.00€25mg264.00€50mg423.00€100mg640.00€Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:Yellow SolidMolecular weight:547.99Ref: TM-T22436
1mg92.00€2mg128.00€5mg178.00€1mL*10mM (DMSO)243.00€10mg268.00€25mg439.00€50mg610.00€100mg820.00€200mg1,099.00€SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formula:C18H22N4O4Purity:99.74%Color and Shape:White SolidMolecular weight:358.39Ref: TM-T6012
1mg34.00€2mg46.00€5mg70.00€1mL*10mM (DMSO)79.00€10mg105.00€25mg215.00€50mg304.00€100mg427.00€200mg587.00€ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Formula:C19H16BrFN6O2Purity:99.12%Color and Shape:White SolidMolecular weight:459.27Ref: TM-T5475
1mg80.00€5mg173.00€1mL*10mM (DMSO)175.00€10mg261.00€25mg414.00€50mg567.00€100mg767.00€200mg1,018.00€Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purity:97.71% - 99.89%Color and Shape:SolidMolecular weight:439.39Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94Su1498
CAS:Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.Formula:C25H30N2O2Purity:99.89%Color and Shape:SolidMolecular weight:390.52Ref: TM-T3980
1mg38.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg113.00€25mg210.00€50mg311.00€100mg462.00€Regorafenib Hydrochloride
CAS:Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formula:C21H16Cl2F4N4O3Purity:99.56%Color and Shape:SolidMolecular weight:519.28
