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VEGFR

VEGFR

VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 268 products of "VEGFR"

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  • VEGFR-2-IN-9

    CAS:
    <p>VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.</p>
    Formula:C23H25N3O3
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:391.46
  • VEGFR-2-IN-37

    CAS:
    <p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>
    Formula:C18H16N2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.4
  • VEGFR2-IN-3

    CAS:
    <p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>
    Formula:C26H28ClN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:509.98
  • WAY-600

    CAS:
    <p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>
    Formula:C28H30N8O
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:494.59
  • VEGFR2-IN-1

    CAS:
    <p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>
    Formula:C22H18N6S
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:398.48
  • Lucitanib dihydrochloride

    CAS:
    <p>Lucitanib dihydrochloride (E-3810 dihydrochloride) is an efficient VEGFR1-3, FGFR1-3, and PDGFRalpha/β inhibitor, used in metastatic breast cancer research.</p>
    Formula:C26H27Cl2N3O4
    Color and Shape:Solid
    Molecular weight:516.42
  • VEGFR/PDGFR-IN-1

    CAS:
    <p>VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.</p>
    Formula:C17H21N5O3
    Color and Shape:Solid
    Molecular weight:343.38
  • VEGFR-2-IN-65

    CAS:
    <p>VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.</p>
    Formula:C21H18N2O3
    Color and Shape:Solid
    Molecular weight:346.379