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PDGFR

PDGFR

PDGFR (platelet-derived growth factor receptor) inhibitors are compounds that block the signaling of PDGFR, a receptor involved in cell growth, proliferation, and angiogenesis. PDGFR plays a significant role in the development of the blood vessels that supply tumors. Inhibiting PDGFR can therefore prevent angiogenesis, making these inhibitors valuable in cancer therapy. At CymitQuimica, we provide a selection of high-quality PDGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 127 products of "PDGFR"

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  • BMS-605541

    CAS:

    BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).

    Formula:C19H17F2N5OS
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:401.43

    Ref: TM-T26852

    10mg
    37.00€
    25mg
    72.00€
    50mg
    105.00€
  • SU16f

    CAS:
    SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.
    Formula:C24H22N2O3
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:386.44

    Ref: TM-T16947

    1mg
    44.00€
    5mg
    92.00€
    10mg
    120.00€
    25mg
    192.00€
    50mg
    286.00€
    100mg
    414.00€
    1mL*10mM (DMSO)
    93.00€
  • Chiauranib

    CAS:

    Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.

    Formula:C27H21N3O3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:435.47

    Ref: TM-T35570

    1mg
    70.00€
    5mg
    153.00€
    10mg
    259.00€
    25mg
    520.00€
    50mg
    748.00€
    100mg
    1,026.00€
    200mg
    1,378.00€
  • Tyrphostin AG1433

    CAS:
    Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).
    Formula:C16H14N2O2
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:266.29

    Ref: TM-T13238

    2mg
    42.00€
    5mg
    62.00€
    10mg
    92.00€
    25mg
    160.00€
    50mg
    236.00€
    100mg
    353.00€
    1mL*10mM (DMSO)
    71.00€
  • TG 100572 Hydrochloride

    CAS:
    TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.
    Formula:C26H27Cl2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:512.43

    Ref: TM-T13156L

    1mg
    359.00€
  • 2-Methyl-3-phenylquinoxaline

    CAS:
    2-Methyl-3-phenylquinoxaline (compound 38) serves as an effective inhibitor of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase (PDGF-RTK), exhibiting significant inhibitory activity against the full-length PDGFR kinase in intact cells (IC50 greater than 100 μM).
    Formula:C15H12N2
    Color and Shape:Solid
    Molecular weight:220.27

    Ref: TM-T201514

    10mg
    To inquire
    50mg
    To inquire
  • CMV-423

    CAS:
    CMV-423 is an antiviral agent exhibiting effective in vitro activity against beta-herpesviruses, including Human Cytomegalovirus (HCMV), Human Herpesvirus 6 (HHV-6), and Human Herpesvirus 7 (HHV-7). It is utilized in antiviral research.
    Formula:C14H14ClN3O
    Color and Shape:Solid
    Molecular weight:275.73

    Ref: TM-T201513

    10mg
    To inquire
    50mg
    To inquire