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PDGFR

PDGFR

PDGFR (platelet-derived growth factor receptor) inhibitors are compounds that block the signaling of PDGFR, a receptor involved in cell growth, proliferation, and angiogenesis. PDGFR plays a significant role in the development of the blood vessels that supply tumors. Inhibiting PDGFR can therefore prevent angiogenesis, making these inhibitors valuable in cancer therapy. At CymitQuimica, we provide a selection of high-quality PDGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.

Found 126 products of "PDGFR"

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  • Chiauranib
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    Chiauranib

    CAS:
    <p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>
    Formula:C27H21N3O3
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:435.47

    Ref: TM-T35570

  • SU16f
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    SU16f

    CAS:
    <p>SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.</p>
    Formula:C24H22N2O3
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:386.44

    Ref: TM-T16947

  • BMS-605541
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    BMS-605541

    CAS:
    <p>BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).</p>
    Formula:C19H17F2N5OS
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:401.43

    Ref: TM-T26852

  • TG 100572 Hydrochloride
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    TG 100572 Hydrochloride

    CAS:
    <p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>
    Formula:C26H27Cl2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:512.43

    Ref: TM-T13156L

  • Tyrphostin AG1433
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    Tyrphostin AG1433

    CAS:
    <p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>
    Formula:C16H14N2O2
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:266.29

    Ref: TM-T13238

  • 2-Methyl-3-phenylquinoxaline
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    2-Methyl-3-phenylquinoxaline

    CAS:
    <p>2-Methyl-3-phenylquinoxaline (compound 38) serves as an effective inhibitor of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase (PDGF-RTK), exhibiting significant inhibitory activity against the full-length PDGFR kinase in intact cells (IC50 greater than 100 μM).</p>
    Formula:C15H12N2
    Color and Shape:Solid
    Molecular weight:220.27

    Ref: TM-T201514