PDGFR
PDGFR (platelet-derived growth factor receptor) inhibitors are compounds that block the signaling of PDGFR, a receptor involved in cell growth, proliferation, and angiogenesis. PDGFR plays a significant role in the development of the blood vessels that supply tumors. Inhibiting PDGFR can therefore prevent angiogenesis, making these inhibitors valuable in cancer therapy. At CymitQuimica, we provide a selection of high-quality PDGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 130 products for "PDGFR".
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Ansornitinib
CAS:Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.Formula:C30H32N6O4Purity:99.24%Color and Shape:SolidMolecular weight:540.61E-4177
CAS:E-4177 is an angiotensin II type 1 receptor (AT1R) antagonist and can be used to study cardiovascular diseases.Formula:C24H21N3O2Purity:98.67% - 99.57%Color and Shape:White SolidMolecular weight:383.44PDGFRα kinase inhibitor 1
CAS:PDGFRα kinase inhibitor 1 is a type II PDGFRα kinase inhibitor that inhibits both PDGFRα and PDGFRβ.Formula:C34H34N8O2Purity:99.78% - 99.84%Color and Shape:Yellow SolidMolecular weight:586.69Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47Ref: TM-T35570
1mg66.00€5mg144.00€1mL*10mM (DMSO)157.00€10mg245.00€25mg492.00€50mg710.00€100mg973.00€BMS-605541
CAS:BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).Formula:C19H17F2N5OSPurity:98.71%Color and Shape:White SolidMolecular weight:401.43SU16f
CAS:SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Formula:C24H22N2O3Purity:97.69%Color and Shape:Red SolidMolecular weight:386.44TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Formula:C26H27Cl2N5O2Purity:98%Color and Shape:SolidMolecular weight:512.43Tyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formula:C16H14N2O2Purity:98.47%Color and Shape:SolidMolecular weight:266.29CMV-423
CAS:CMV-423 is an antiviral agent exhibiting effective in vitro activity against beta-herpesviruses, including Human Cytomegalovirus (HCMV), Human Herpesvirus 6 (HHV-6), and Human Herpesvirus 7 (HHV-7). It is utilized in antiviral research.Formula:C14H14ClN3OColor and Shape:SolidMolecular weight:275.732-Methyl-3-phenylquinoxaline
CAS:2-Methyl-3-phenylquinoxaline (compound 38) serves as an effective inhibitor of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase (PDGF-RTK), exhibiting significant inhibitory activity against the full-length PDGFR kinase in intact cells (IC50 greater than 100 μM).Formula:C15H12N2Color and Shape:SolidMolecular weight:220.27
